| Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis K Yamanaka, SJ Chun, S Boillee, N Fujimori-Tonou, H Yamashita, ... Nature neuroscience 11 (3), 251-253, 2008 | 1299 | 2008 |
| miRNA malfunction causes spinal motor neuron disease S Haramati, E Chapnik, Y Sztainberg, R Eilam, R Zwang, N Gershoni, ... Proceedings of the National Academy of Sciences 107 (29), 13111-13116, 2010 | 367 | 2010 |
| Expression and function of the cholinergic system in immune cells T Fujii, M Mashimo, Y Moriwaki, H Misawa, S Ono, K Horiguchi, ... Frontiers in immunology 8, 1085, 2017 | 330 | 2017 |
| A null mutation in the human CNTF gene is not causally related to neurological diseases R Takahashi, H Yokoji, H Misawa, M Hayashi, J Hu, T Deguchi Nature genetics 7 (1), 79-84, 1994 | 264 | 1994 |
| Expression and function of genes encoding cholinergic components in murine immune cells K Kawashima, K Yoshikawa, YX Fujii, Y Moriwaki, H Misawa Life sciences 80 (24-25), 2314-2319, 2007 | 262 | 2007 |
| Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: in situ hybridization … T Ichikawa, K Ajiki, J Matsuura, H Misawa Journal of chemical neuroanatomy 13 (1), 23-39, 1997 | 256 | 1997 |
| Loss of TDP-43 causes age-dependent progressive motor neuron degeneration Y Iguchi, M Katsuno, J Niwa, S Takagi, S Ishigaki, K Ikenaka, K Kawai, ... Brain 136 (5), 1371-1382, 2013 | 218 | 2013 |
| Critical roles of acetylcholine and the muscarinic and nicotinic acetylcholine receptors in the regulation of immune function K Kawashima, T Fujii, Y Moriwaki, H Misawa Life sciences 91 (21-22), 1027-1032, 2012 | 209 | 2012 |
| Physiological functions of the cholinergic system in immune cells T Fujii, M Mashimo, Y Moriwaki, H Misawa, S Ono, K Horiguchi, ... Journal of pharmacological sciences 134 (1), 1-21, 2017 | 201 | 2017 |
| Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis Y Tashiro, M Urushitani, H Inoue, M Koike, Y Uchiyama, M Komatsu, ... Journal of Biological Chemistry 287 (51), 42984-42994, 2012 | 182 | 2012 |
| Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2 T Hideyama, T Yamashita, T Suzuki, S Tsuji, M Higuchi, PH Seeburg, ... Journal of Neuroscience 30 (36), 11917-11925, 2010 | 180 | 2010 |
| Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model M Tateno, H Sadakata, M Tanaka, S Itohara, RM Shin, M Miura, ... Human molecular genetics 13 (19), 2183-2196, 2004 | 166 | 2004 |
| Neurotransmitter release regulated by a MALS–liprin-α presynaptic complex O Olsen, KA Moore, M Fukata, T Kazuta, JC Trinidad, FW Kauer, M Streuli, ... The Journal of cell biology 170 (7), 1127-1134, 2005 | 161 | 2005 |
| Evidence for active acetylcholine metabolism in human amniotic epithelial cells: applicable to intracerebral allografting for neurologic disease N Sakuragawa, H Misawa, K Ohsugi, K Kakishita, T Ishii, R Thangavel, ... Neuroscience letters 232 (1), 53-56, 1997 | 149 | 1997 |
| The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model H Inoue, K Tsukita, T Iwasato, Y Suzuki, M Tomioka, M Tateno, M Nagao, ... The EMBO journal 22 (24), 6665-6674, 2003 | 139 | 2003 |
| Gene expression of mouse choline acetyltransferase. Alternative splicing and identification of a highly active promoter region. H Misawa, K Ishii, T Deguchi Journal of Biological Chemistry 267 (28), 20392-20399, 1992 | 134 | 1992 |
| Ubiquitous expression of acetylcholine and its biological functions in life forms without nervous systems K Kawashima, H Misawa, Y Moriwaki, YX Fujii, T Fujii, Y Horiuchi, ... Life sciences 80 (24-25), 2206-2209, 2007 | 132 | 2007 |
| Induction of choline acetyltransferase mRNA in human mononuclear leukocytes stimulated by phytohemagglutinin, a T-cell activator T Fujii, S Yamada, Y Watanabe, H Misawa, S Tajima, K Fujimoto, ... Journal of neuroimmunology 82 (1), 101-107, 1998 | 130 | 1998 |
| The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons T Mori, Z Yuxing, H Takaki, M Takeuchi, K Iseki, S Hagino, J Kitanaka, ... European Journal of Neuroscience 19 (12), 3129-3141, 2004 | 111 | 2004 |
| Distribution of the high-affinity choline transporter in the central nervous system of the rat H Misawa, K Nakata, J Matsuura, M Nagao, T Okuda, T Haga Neuroscience 105 (1), 87-98, 2001 | 111 | 2001 |
