Host immune system gene targeting by a viral miRNA N Stern-Ginossar, N Elefant, A Zimmermann, DG Wolf, N Saleh, M Biton, ... Science 317 (5836), 376-381, 2007 | 810 | 2007 |
Stromal microenvironment shapes the intratumoral architecture of pancreatic cancer M Ligorio, S Sil, J Malagon-Lopez, LT Nieman, S Misale, M Di Pilato, ... Cell 178 (1), 160-175. e27, 2019 | 441 | 2019 |
Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D N Stern-Ginossar, C Gur, M Biton, E Horwitz, M Elboim, N Stanietsky, ... Nature immunology 9 (9), 1065-1073, 2008 | 396 | 2008 |
Tumor necrosis factor-α blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation M Sade-Feldman, J Kanterman, E Ish-Shalom, M Elnekave, E Horwitz, ... Immunity 38 (3), 541-554, 2013 | 336 | 2013 |
Mutant KRAS is a druggable target for pancreatic cancer E Zorde Khvalevsky, R Gabai, IH Rachmut, E Horwitz, Z Brunschwig, ... Proceedings of the National Academy of Sciences 110 (51), 20723-20728, 2013 | 315 | 2013 |
p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion A Helman, A Klochendler, N Azazmeh, Y Gabai, E Horwitz, S Anzi, ... Nature medicine 22 (4), 412-420, 2016 | 311 | 2016 |
Epithelial microRNAs regulate gut mucosal immunity via epithelium–T cell crosstalk M Biton, A Levin, M Slyper, I Alkalay, E Horwitz, H Mor, S Kredo-Russo, ... Nature immunology 12 (3), 239-246, 2011 | 222 | 2011 |
Human and Mouse VEGFA-Amplified Hepatocellular Carcinomas Are Highly Sensitive to Sorafenib Treatment E Horwitz, I Stein, M Andreozzi, J Nemeth, A Shoham, O Pappo, ... Cancer discovery 4 (6), 730-743, 2014 | 191 | 2014 |
NKp46-mediated killing of human and mouse hepatic stellate cells attenuates liver fibrosis C Gur, S Doron, S Kfir-Erenfeld, E Horwitz, L Abu-Tair, R Safadi, ... Gut 61 (6), 885-893, 2012 | 187 | 2012 |
S100A8andS100A9are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis J Németh, I Stein, D Haag, A Riehl, T Longerich, E Horwitz, K Breuhahn, ... Hepatology 50 (4), 1251-1262, 2009 | 180 | 2009 |
The lipogenic regulator SREBP2 induces transferrin in circulating melanoma cells and suppresses ferroptosis X Hong, W Roh, RJ Sullivan, KHK Wong, BS Wittner, H Guo, TD Dubash, ... Cancer discovery 11 (3), 678-695, 2021 | 128 | 2021 |
PI3K/AKT/mTOR‐dependent stabilization of oncogenic far‐upstream element binding proteins in hepatocellular carcinoma cells J Samarin, V Laketa, M Malz, S Roessler, I Stein, E Horwitz, S Singer, ... Hepatology 63 (3), 813-826, 2016 | 78 | 2016 |
Pancreatic β-cells express the fetal islet hormone gastrin in rodent and human diabetes T Dahan, O Ziv, E Horwitz, H Zemmour, J Lavi, A Swisa, G Leibowitz, ... Diabetes 66 (2), 426-436, 2017 | 57 | 2017 |
Critical role for IL-1β in DNA damage-induced mucositis N Kanarek, SI Grivennikov, M Leshets, A Lasry, I Alkalay, E Horwitz, ... Proceedings of the National Academy of Sciences 111 (6), E702-E711, 2014 | 57 | 2014 |
Sleeve gastrectomy improves glycemia independent of weight loss by restoring hepatic insulin sensitivity S Abu-Gazala, E Horwitz, R Ben-Haroush Schyr, A Bardugo, H Israeli, ... Diabetes 67 (6), 1079-1085, 2018 | 56 | 2018 |
β-Cell DNA damage response promotes islet inflammation in type 1 diabetes E Horwitz, L Krogvold, S Zhitomirsky, A Swisa, M Fischman, T Lax, ... Diabetes 67 (11), 2305-2318, 2018 | 44 | 2018 |
Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCFβ-TrCP by single substrate depletion N Kanarek, E Horwitz, I Mayan, M Leshets, G Cojocaru, M Davis, ... Genes & development 24 (5), 470-477, 2010 | 44 | 2010 |
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer H Guo, G Golczer, BS Wittner, A Langenbucher, M Zachariah, TD Dubash, ... Molecular cell 81 (19), 4041-4058. e15, 2021 | 25 | 2021 |
The expression of the beta cell-derived autoimmune ligand for the killer receptor nkp46 is attenuated in type 2 diabetes C Gur, J Enk, E Weitman, E Bachar, Y Suissa, G Cohen, RBH Schyr, ... PloS one 8 (8), e74033, 2013 | 18 | 2013 |
Human anti‐NKp46 antibody for studies of NKp46‐dependent NK cell function and its applications for type 1 diabetes and cancer research O Berhani, A Glasner, S Kahlon, A Duev‐Cohen, R Yamin, E Horwitz, ... European journal of immunology 49 (2), 228-241, 2019 | 17 | 2019 |