| Atomic structures of amyloid cross-β spines reveal varied steric zippers MR Sawaya, S Sambashivan, R Nelson, MI Ivanova, SA Sievers, ... Nature 447 (7143), 453-457, 2007 | 2552 | 2007 |
| Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation SA Sievers, J Karanicolas, HW Chang, A Zhao, L Jiang, O Zirafi, ... Nature 475 (7354), 96-100, 2011 | 517 | 2011 |
| The 3D profile method for identifying fibril-forming segments of proteins MJ Thompson, SA Sievers, J Karanicolas, MI Ivanova, D Baker, ... Proceedings of the National Academy of Sciences 103 (11), 4074-4078, 2006 | 456 | 2006 |
| Molecular basis for insulin fibril assembly MI Ivanova, SA Sievers, MR Sawaya, JS Wall, D Eisenberg Proceedings of the National Academy of Sciences 106 (45), 18990-18995, 2009 | 430 | 2009 |
| Atomic structure of the cross‐β spine of islet amyloid polypeptide (amylin) JJW Wiltzius, SA Sievers, MR Sawaya, D Cascio, D Popov, C Riekel, ... Protein Science 17 (9), 1467-1474, 2008 | 397 | 2008 |
| Function of novel anti-CD19 chimeric antigen receptors with human variable regions is affected by hinge and transmembrane domains L Alabanza, M Pegues, C Geldres, V Shi, JJW Wiltzius, SA Sievers, ... Molecular Therapy 25 (11), 2452-2465, 2017 | 282 | 2017 |
| Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process JJW Wiltzius, SA Sievers, MR Sawaya, D Eisenberg Protein Science 18 (7), 1521-1530, 2009 | 241 | 2009 |
| Towards a pharmacophore for amyloid M Landau, MR Sawaya, KF Faull, A Laganowsky, L Jiang, SA Sievers, ... PLoS biology 9 (6), e1001080, 2011 | 239 | 2011 |
| Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller NT Freund, H Wang, L Scharf, L Nogueira, JA Horwitz, Y Bar-On, ... Science translational medicine 9 (373), eaal2144, 2017 | 166 | 2017 |
| Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS MI Ivanova, SA Sievers, EL Guenther, LM Johnson, DD Winkler, ... Proceedings of the National Academy of Sciences 111 (1), 197-201, 2014 | 158 | 2014 |
| Structure-based design of functional amyloid materials D Li, EM Jones, MR Sawaya, H Furukawa, F Luo, M Ivanova, SA Sievers, ... Journal of the American Chemical Society 136 (52), 18044-18051, 2014 | 114 | 2014 |
| Structural basis for germline antibody recognition of HIV-1 immunogens L Scharf, AP West Jr, SA Sievers, C Chen, S Jiang, H Gao, MD Gray, ... Elife 5, e13783, 2016 | 81 | 2016 |
| Activation of CAR and non-CAR T cells within the tumor microenvironment following CAR T cell therapy PH Chen, M Lipschitz, JL Weirather, C Jacobson, P Armand, K Wright, ... JCI insight 5 (12), 2020 | 76 | 2020 |
| Draft crystal structure of the vault shell at 9-Å resolution DH Anderson, VA Kickhoefer, SA Sievers, LH Rome, D Eisenberg PLoS biology 5 (11), e318, 2007 | 73 | 2007 |
| Antibody engineering for increased potency, breadth and half-life SA Sievers, L Scharf, AP West Jr, PJ Bjorkman Current opinion in HIV and AIDS 10 (3), 151-159, 2015 | 61 | 2015 |
| A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo NT Freund, JA Horwitz, L Nogueira, SA Sievers, L Scharf, JF Scheid, ... PLoS pathogens 11 (10), e1005238, 2015 | 55 | 2015 |
| Identification and Biochemical Characterization of Serine Hydroxymethyl Transferase in the Hydrogenosome of Trichomonas vaginalis M Mukherjee, SA Sievers, MT Brown, PJ Johnson Eukaryotic Cell 5 (12), 2072-2078, 2006 | 30 | 2006 |
| The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity SW French, DW Dawson, HW Chen, RN Rainey, SA Sievers, CE Balatoni, ... Cancer letters 248 (2), 198-210, 2007 | 28 | 2007 |
| Crystal structures of amyloidogenic segments of human transthyretin L Saelices, SA Sievers, MR Sawaya, DS Eisenberg Protein Science 27 (7), 1295-1303, 2018 | 27 | 2018 |
| Development of KITE-585: a fully human BCMA CAR T-cell therapy for the treatment of multiple myeloma GB Adams, J Feng, A Ghogha, A Mardiros, J Murakami, T Phung, ... Cancer Research 77 (13_Supplement), 4979-4979, 2017 | 10 | 2017 |
David S. EisenbergPaul Boyer Professor, HHMI-UCLAVerified email at mbi.ucla.edu
