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Elina Siirola
Elina Siirola
GDC Bioreactions, Novartis
Verified email at novartis.com
Title
Cited by
Cited by
Year
Asymmetric Preparation of prim-, sec-, and tert-Amines Employing Selected Biocatalysts
W Kroutil, EM Fischereder, CS Fuchs, H Lechner, FG Mutti, D Pressnitz, ...
Organic process research & development 17 (5), 751-759, 2013
1362013
Novel carbon–carbon bond formations for biocatalysis
V Resch, JH Schrittwieser, E Siirola, W Kroutil
Current opinion in biotechnology 22 (6), 793-799, 2011
1102011
Understanding and Overcoming the Limitations of Bacillus badius and Caldalkalibacillus thermarum Amine Dehydrogenases for Biocatalytic Reductive Amination
A Pushpanath, E Siirola, A Bornadel, D Woodlock, U Schell
ACS Catalysis 7 (5), 3204-3209, 2017
772017
Machine-Directed Evolution of an Imine Reductase for Activity and Stereoselectivity
EJ Ma, E Siirola, C Moore, A Kummer, M Stoeckli, M Faller, C Bouquet, ...
ACS Catalysis 11 (20), 12433-12445, 2021
582021
Asymmetric Synthesis of 3‐Substituted Cyclohexylamine Derivatives from Prochiral Diketones via Three Biocatalytic Steps
E Siirola, FG Mutti, B Grischek, SF Hoefler, WMF Fabian, G Grogan, ...
Advanced Synthesis & Catalysis 355 (9), 1703-1708, 2013
482013
C C Hydrolases for Biocatalysis
E Siirola, A Frank, G Grogan, W Kroutil
Advanced Synthesis & Catalysis 355 (9), 1677-1691, 2013
332013
Intensified biocatalytic production of enantiomerically pure halophenylalanines from acrylic acids using ammonium carbamate as the ammonia source
NJ Weise, ST Ahmed, F Parmeggiani, E Siirola, A Pushpanath, U Schell, ...
Catalysis Science & Technology 6 (12), 4086-4089, 2016
312016
Exploring productive sequence space in directed evolution using binary patterning versus conventional mutagenesis strategies
Z Sun, PT Salas, E Siirola, R Lonsdale, MT Reetz
Bioresources and Bioprocessing 3 (1), 1-8, 2016
232016
Synthesis of new thiophene, furan and pyridine substituted 1, 2, 4, 5-oxadiazaboroles
Y Dürüst, M Akcan, O Martiskainen, E Siirola, K Pihlaja
Polyhedron 27 (3), 999-1007, 2008
232008
Tolerance of β‐diketone hydrolases as representatives of the crotonase superfamily towards organic solvents
E Siirola, B Grischek, D Clay, A Frank, G Grogan, W Kroutil
Biotechnology and bioengineering 108 (12), 2815-2822, 2011
132011
Enzymatic Bioconjugation: A Perspective from the Pharmaceutical Industry
A Debon, E Siirola, R Snajdrova
JACS Au 3 (5), 1267-1283, 2023
122023
Regio‐ and Stereoselective Lipase‐Catalysed Acylation of Methyl α‐D‐Glycopyranosides with Fluorinated β‐Lactams
R Sundell, E Siirola, LT Kanerva
European Journal of Organic Chemistry 2014 (30), 6753-6760, 2014
92014
Mutational Analysis of the C–C Bond Cleaving Enzyme Phloretin Hydrolase from Eubacterium ramulus
A Frank, E Siirola, W Kroutil, G Grogan
Topics in Catalysis 57, 376-384, 2014
92014
Organic solvent tolerance of retro-Friedel–Crafts Hydrolases
E Siirola, W Kroutil
Topics in Catalysis 57, 392-400, 2014
62014
Evolution of Biocatalysis at Novartis over the last 40 Years
E Siirola, F Eggimann, C Moore, K Schroer, A Vargas, T Peschke, ...
Chimia 77 (6), 376-383, 2023
22023
Biocatalytic Reduction of Activated Cinnamic Acid Derivatives: Asymmetric reduction of C= C double bonds using Johnson Matthey enzymes
S Staniland, T Angelini, A Pushpanath, A Bornadel, E Siirola, S Bisagni, ...
Johnson Matthey Technology Review 64 (4), 529-536, 2020
2020
Cipargamin: Biocatalysis in the Discovery and Development of an Antimalarial Drug
T Ruch, E Siirola, R Snajdrova
Pharmaceutical Biocatalysis, 559-577, 2019
2019
Johnson Matthey: A Technology Provider Perspective to Biocatalysis in the Fine Chemicals Industry
E Siirola, A Pushpanath, DM Schofield, P Braiuca
Biocatalysis, 168-189, 2017
2017
Cascade reactions to access optically pure prim-, sec-and test-amines
RC Simon, J Sattler, KC Tauber, E Siirola, J Schrittwieser, V Resch, ...
Biocat 2012, 2012
2012
Biocatalytic CC bond formation and CC cleavage
W Kroutil, J Schrittwieser, V Resch, J Sattler, B Seisser, E Siirola, ...
2011
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