| Role of Oxidative Stress in Hepatic and Extrahepatic Dysfunctions during Nonalcoholic Fatty Liver Disease (NAFLD) A Gonzalez, C Huerta-Salgado, J Orozco-Aguilar, F Aguirre, F Tacchi, ... Oxidative Medicine and Cellular Longevity 2020, 1617805, 2020 | 73 | 2020 |
| Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection P Castro-Córdova, P Mora-Uribe, R Reyes-Ramírez, G Cofré-Araneda, ... Nature communications 12 (1), 1140, 2021 | 66 | 2021 |
| Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements G Ramírez-Vargas, D López-Ureña, A Badilla, J Orozco-Aguilar, T Murillo, ... Scientific reports 8 (1), 13951, 2018 | 39 | 2018 |
| Toxin B variants from Clostridium difficile strains VPI 10463 and NAP1/027 share similar substrate profile and cellular intoxication kinetics but use different host cell entry … D López-Ureña, J Orozco-Aguilar, Y Chaves-Madrigal, A Ramírez-Mata, ... Toxins 11 (348), 2019 | 29 | 2019 |
| Analysis of TcdB proteins within the hypervirulent clade 2 reveals an impact of RhoA glucosylation on Clostridium difficile proinflammatory activities C Quesada-Gómez, D López-Ureña, N Chumbler, HK Kroh, ... Infection and immunity 84 (3), 856-865, 2016 | 28 | 2016 |
| SARS-CoV-2/renin–angiotensin system: deciphering the clues for a couple with potentially harmful effects on skeletal muscle A Gonzalez, J Orozco-Aguilar, O Achiardi, F Simon, C Cabello-Verrugio International Journal of Molecular Sciences 21 (21), 7904, 2020 | 26 | 2020 |
| Redox-dependent effects in the physiopathological role of bile acids J Orozco-Aguilar, F Simon, C Cabello-Verrugio Oxidative medicine and cellular longevity 2021, 2021 | 11 | 2021 |
| Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection. Nat Commun 12: 1140 P Castro-Cordova, P Mora-Uribe, R Reyes-Ramirez, G Cofre-Araneda, ... | 7 | 2021 |
| In vivo animal models confirm an increased virulence potential and pathogenicity of the NAP1/RT027/ST01 genotype within the Clostridium difficile MLST Clade 2 J Orozco-Aguilar, A Alfaro-Alarcón, L Acuña-Amador, E Chaves-Olarte, ... Gut pathogens 12, 1-10, 2020 | 7 | 2020 |
| Toxin B variants from Clostridium difficile strains VPI 10463 and NAP1/027 share similar substrate profile and cellular intoxication kinetics but use different host cell entry … D López-Ureña, J Orozco-Aguilar, Y Chaves-Madrigal, A Ramirez-Mata, ... | 6 | 2019 |
| Cholic and deoxycholic acids induce mitochondrial dysfunction, impaired biogenesis and autophagic flux in skeletal muscle cells J Abrigo, H Olguín, F Tacchi, J Orozco-Aguilar, M Valero-Breton, J Soto, ... Biological Research 56 (1), 30, 2023 | 5 | 2023 |
| Ursodeoxycholic acid induces sarcopenia associated with decreased protein synthesis and autophagic flux J Orozco-Aguilar, F Tacchi, F Aguirre, M Valero-Breton, ... Biological Research 56 (1), 28, 2023 | 4 | 2023 |
| Scaffold biomaterials and nano-based therapeutic strategies for skeletal muscle regeneration F Tacchi, J Orozco-Aguilar, D Gutiérrez, F Simon, J Salazar, C Vilos, ... Nanomedicine 16 (28), 2521-2538, 2021 | 3 | 2021 |
| Absence of renal protection of an aqueous extract of lemongrass (Cymbopogon citratus) cultivated in Costa Rica, using a model of acute renal failure in Wistar rats N Apú-Leitón, JM Fallas-Ramírez, J Orozco-Aguilar, A Rodríguez-Arrieta, ... Asian Journal of Pharmaceutical Research and Development 7 (6), 11-19, 2019 | 3 | 2019 |
| Advances in Molecular Pathology F Simon, C Bernabeu Springer Nature, 2023 | 2 | 2023 |
| Clostridioides difficile spore-entry into intestinal epithelial cells contributes to recurrence of the disease P Castro-Córdova, P Mora-Uribe, R Reyes-Ramírez, G Cofré-Araneda, ... bioRxiv, 2020.09. 11.291104, 2020 | 2 | 2020 |
| Absence of Renal Protection of an Aqueous Extract of the Costa Rican Plant Calzoncillo (Passiflora biflora), using a Model of Acute Kidney Injury (AKI) in Female Wistar Rat EZ Murillo, JJM Román, JA Rodríguez World J. Pharm. Res. 33 World J. Pharm. Res. SJIF Impact Factor 8 (9), 33-56, 2020 | 2 | 2020 |
| Bile acids alter the autophagy and mitogenesis in skeletal muscle cells F Tacchi, J Orozco-Aguilar, M Valero-Breton, C Cabello-Verrugio Advances in Molecular Pathology, 183-199, 2023 | 1 | 2023 |
| Efecto del extracto acuoso de hojas de Licania platypus (Hemsl.) Fritsh. Sobre la protección gástrica y la motilidad gastrointestinal. JO Aguilar, MC Rojas, JS Flores, GA Barboza, EC García, JAM Acuña, ... Revista Médica de la Universidad de Costa Rica 11 (2), 2017 | 1 | 2017 |
| Differential Fibrotic Response of Muscle Fibroblasts, Myoblasts, and Myotubes to Cholic and Deoxycholic Acids L Maldonado, J Orozco-Aguilar, M Valero-Breton, F Tacchi, ... Advances in Molecular Pathology, 219-234, 2023 | | 2023 |
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