| Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies Y Aye, M Li, MJC Long, RS Weiss Oncogene 34 (16), 2011-2021, 2015 | 411 | 2015 |
| Redox signaling by reactive electrophiles and oxidants S Parvez, MJC Long, JR Poganik, Y Aye Chemical reviews 118 (18), 8798-8888, 2018 | 280 | 2018 |
| Copper-catalyzed asymmetric conjugate reduction as a route to novel β-azaheterocyclic acid derivatives MP Rainka, Y Aye, SL Buchwald Proceedings of the National Academy of Sciences 101 (16), 5821-5823, 2004 | 108 | 2004 |
| Vinyl‐, Propargyl‐, and Allenylsilicon Reagents in Asymmetric Synthesis: A Relatively Untapped Resource of Environmentally Benign Reagents MJ Curtis‐Long, Y Aye Chemistry–A European Journal 15 (22), 5402-5416, 2009 | 93 | 2009 |
| Mechanistic studies of semicarbazone triapine targeting human ribonucleotide reductase in vitro and in mammalian cells: tyrosyl radical quenching not involving reactive oxygen … Y Aye, MJC Long, JA Stubbe Journal of Biological Chemistry 287 (42), 35768-35778, 2012 | 86 | 2012 |
| On-demand targeting: investigating biology with proximity-directed chemistry MJC Long, JR Poganik, Y Aye Journal of the American Chemical Society 138 (11), 3610-3622, 2016 | 78 | 2016 |
| Privileged electrophile sensors: a resource for covalent drug development MJC Long, Y Aye Cell chemical biology 24 (7), 787-800, 2017 | 72 | 2017 |
| Asymmetric, anti-Selective Scandium-Catalyzed Sakurai Additions to Glyoxyamide. Applications to the Syntheses of N-Boc d-Alloisoleucine and d-Isoleucine DA Evans, Y Aye, J Wu Organic Letters 8 (10), 2071-2073, 2006 | 72 | 2006 |
| Clofarabine 5′-di and-triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit Y Aye, JA Stubbe Proceedings of the National Academy of Sciences 108 (24), 9815-9820, 2011 | 71 | 2011 |
| Modular total synthesis and cell-based anticancer activity evaluation of ouabagenin and other cardiotonic steroids with varying degrees of oxygenation HR Khatri, B Bhattarai, W Kaplan, Z Li, MJ Curtis Long, Y Aye, P Nagorny Journal of the American Chemical Society 141 (12), 4849-4860, 2019 | 70 | 2019 |
| T-REX on-demand redox targeting in live cells S Parvez, MJC Long, HY Lin, Y Zhao, JA Haegele, VN Pham, DK Lee, ... Nature protocols 11 (12), 2328-2356, 2016 | 67 | 2016 |
| A generalizable platform for interrogating target-and signal-specific consequences of electrophilic modifications in redox-dependent cell signaling HY Lin, JA Haegele, MT Disare, Q Lin, Y Aye Journal of the American Chemical Society 137 (19), 6232-6244, 2015 | 67 | 2015 |
| Temporally controlled targeting of 4-hydroxynonenal to specific proteins in living cells X Fang, Y Fu, MJC Long, JA Haegele, EJ Ge, S Parvez, Y Aye Journal of the American Chemical Society 135 (39), 14496-14499, 2013 | 67 | 2013 |
| Substoichiometric hydroxynonenylation of a single protein recapitulates whole-cell-stimulated antioxidant response S Parvez, Y Fu, J Li, MJC Long, HY Lin, DK Lee, GS Hu, Y Aye Journal of the American Chemical Society 137 (1), 10-13, 2015 | 63 | 2015 |
| Akt3 is a privileged first responder in isozyme-specific electrophile response MJC Long, S Parvez, Y Zhao, SL Surya, Y Wang, S Zhang, Y Aye Nature chemical biology 13 (3), 333-338, 2017 | 61 | 2017 |
| Enantioselective scandium-catalyzed vinylsilane additions: A new approach to the synthesis of enantiopure β, γ-unsaturated α-hydroxy acid derivatives DA Evans, Y Aye Journal of the American Chemical Society 128 (34), 11034-11035, 2006 | 58 | 2006 |
| Ube2V2 is a Rosetta stone bridging redox and ubiquitin codes, coordinating DNA damage responses Y Zhao, MJC Long, Y Wang, S Zhang, Y Aye ACS central science 4 (2), 246-259, 2018 | 53 | 2018 |
| Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers Y Aye, EJ Brignole, MJC Long, J Chittuluru, CL Drennan, FJ Asturias, ... Chemistry & biology 19 (7), 799-805, 2012 | 51 | 2012 |
| Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1 JR Poganik, MJC Long, MT Disare, X Liu, SH Chang, T Hla, Y Aye The FASEB Journal 33 (12), 14636, 2019 | 48 | 2019 |
| Parallel kinetic resolution of tert-butyl (RS)-3-oxy-substituted cyclopent-1-ene-carboxylates for the asymmetric synthesis of 3-oxy-substituted cispentacin and transpentacin … Y Aye, SG Davies, AC Garner, PM Roberts, AD Smith, JE Thomson Organic & Biomolecular Chemistry 6 (12), 2195-2203, 2008 | 47 | 2008 |
