| Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size H Cabral, Y Matsumoto, K Mizuno, Q Chen, M Murakami, M Kimura, ... Nature nanotechnology 6 (12), 815-823, 2011 | 2434 | 2011 |
| Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood–brain tumor barrier Y Miura, T Takenaka, K Toh, S Wu, H Nishihara, MR Kano, Y Ino, ... ACS nano 7 (10), 8583-8592, 2013 | 471 | 2013 |
| Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling MR Kano, Y Bae, C Iwata, Y Morishita, M Yashiro, M Oka, T Fujii, ... Proceedings of the National Academy of Sciences 104 (9), 3460-3465, 2007 | 471 | 2007 |
| Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery Y Matsumoto, JW Nichols, K Toh, T Nomoto, H Cabral, Y Miura, ... Nature nanotechnology 11 (6), 533-538, 2016 | 405 | 2016 |
| VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B–PDGFRβ signaling MR Kano, Y Morishita, C Iwata, S Iwasaka, T Watabe, Y Ouchi, ... Journal of cell science 118 (16), 3759-3768, 2005 | 372 | 2005 |
| Autophagy is activated by TGF-β and potentiates TGF-β–mediated growth inhibition in human hepatocellular carcinoma cells K Kiyono, HI Suzuki, H Matsuyama, Y Morishita, A Komuro, MR Kano, ... Cancer research 69 (23), 8844-8852, 2009 | 330 | 2009 |
| Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting M Murakami, H Cabral, Y Matsumoto, S Wu, MR Kano, T Yamori, ... Science translational medicine 3 (64), 64ra2-64ra2, 2011 | 265 | 2011 |
| Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway H Ota, M Eto, MR Kano, T Kahyo, M Setou, S Ogawa, K Iijima, M Akishita, ... Arteriosclerosis, thrombosis, and vascular biology 30 (11), 2205-2211, 2010 | 250 | 2010 |
| Cilostazol inhibits oxidative stress–induced premature senescence via upregulation of Sirt1 in human endothelial cells H Ota, M Eto, MR Kano, S Ogawa, K Iijima, M Akishita, Y Ouchi Arteriosclerosis, thrombosis, and vascular biology 28 (9), 1634-1639, 2008 | 250 | 2008 |
| Inhibition of endogenous TGF-β signaling enhances lymphangiogenesis M Oka, C Iwata, HI Suzuki, K Kiyono, Y Morishita, T Watabe, A Komuro, ... Blood 111 (9), 4571-4579, 2008 | 248 | 2008 |
| Systemically injectable enzyme‐loaded polyion complex vesicles as in vivo nanoreactors functioning in tumors Y Anraku, A Kishimura, M Kamiya, S Tanaka, T Nomoto, K Toh, ... Angewandte Chemie International Edition 55 (2), 560-565, 2016 | 182 | 2016 |
| LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis H Sumida, K Noguchi, Y Kihara, M Abe, K Yanagida, F Hamano, S Sato, ... Blood 116 (23), 5060-5070, 2010 | 175 | 2010 |
| Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis C Iwata, MR Kano, A Komuro, M Oka, K Kiyono, E Johansson, Y Morishita, ... Cancer research 67 (21), 10181-10189, 2007 | 160 | 2007 |
| Systemic targeting of lymph node metastasis through the blood vascular system by using size-controlled nanocarriers H Cabral, J Makino, Y Matsumoto, P Mi, H Wu, T Nomoto, K Toh, ... ACS nano 9 (5), 4957-4967, 2015 | 138 | 2015 |
| Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors Z Ge, Q Chen, K Osada, X Liu, TA Tockary, S Uchida, A Dirisala, T Ishii, ... Biomaterials 35 (10), 3416-3426, 2014 | 135 | 2014 |
| Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor‐β receptor inhibitor on extravasation of nanoparticles from neovasculature MR Kano, Y Komuta, C Iwata, M Oka, Y Shirai, Y Morishita, Y Ouchi, ... Cancer science 100 (1), 173-180, 2009 | 124 | 2009 |
| Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery M Oba, K Miyata, K Osada, RJ Christie, M Sanjoh, W Li, S Fukushima, ... Biomaterials 32 (2), 652-663, 2011 | 118 | 2011 |
| Enhanced in vivo Magnetic Resonance Imaging of Tumors by PEGylated Iron‐Oxide–Gold Core–Shell Nanoparticles with Prolonged Blood Circulation Properties M Kumagai, TK Sarma, H Cabral, S Kaida, M Sekino, N Herlambang, ... Macromolecular rapid communications 31 (17), 1521-1528, 2010 | 112 | 2010 |
| Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles Y Vachutinsky, M Oba, K Miyata, S Hiki, MR Kano, N Nishiyama, ... Journal of controlled release 149 (1), 51-57, 2011 | 101 | 2011 |
| Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells S Ehata, E Johansson, R Katayama, S Koike, A Watanabe, Y Hoshino, ... Oncogene 30 (14), 1693-1705, 2011 | 96 | 2011 |
Kazunori KataokaDirector General, Innovation Center of NanoMed; Professor Emeritus, Univ. TokyoVerified email at bmw.t.u-tokyo.ac.jp
