Evidence that TLR4 is not a receptor for saturated fatty acids but mediates lipid-induced inflammation by reprogramming macrophage metabolism GI Lancaster, KG Langley, NA Berglund, HL Kammoun, S Reibe, ... Cell metabolism 27 (5), 1096-1110. e5, 2018 | 391 | 2018 |
Interaction of the Antimicrobial Peptide Polymyxin B1 with Both Membranes of E. coli: A Molecular Dynamics Study NA Berglund, TJ Piggot, D Jefferies, RB Sessions, PJ Bond, S Khalid PLoS computational biology 11 (4), e1004180, 2015 | 170 | 2015 |
Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub SL Latty, J Sakai, L Hopkins, B Verstak, T Paramo, NA Berglund, ... elife 7, e31377, 2018 | 95 | 2018 |
Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides R Saravanan, DA Holdbrook, J Petrlova, S Singh, NA Berglund, ... Nature Communications 9 (1), 2762, 2018 | 50 | 2018 |
A thermodynamic funnel drives bacterial lipopolysaccharide transfer in the TLR4 pathway RG Huber, NA Berglund, V Kargas, JK Marzinek, DA Holdbrook, S Khalid, ... Structure 26 (8), 1151-1161. e4, 2018 | 35 | 2018 |
Understanding and modelling the interactions of peptides with membranes: from partitioning to self-assembly CH Chen, MCR Melo, N Berglund, A Khan, C de la Fuente-Nunez, ... Current Opinion in Structural Biology 61, 160-166, 2020 | 33 | 2020 |
The role of protein–protein interactions in Toll-like receptor function NA Berglund, V Kargas, ML Ortiz-Suarez, PJ Bond Progress in biophysics and molecular biology 119 (1), 72-83, 2015 | 33 | 2015 |
De-risking drug discovery of intracellular targeting peptides: screening strategies to eliminate false-positive hits S Ng, YC Juang, A Chandramohan, HYK Kaan, A Sadruddin, TY Yuen, ... ACS Medicinal Chemistry Letters 11 (10), 1993-2001, 2020 | 27 | 2020 |
The membranes of Gram-negative bacteria: progress in molecular modelling and simulation S Khalid, NA Berglund, DA Holdbrook, YM Leung, J Parkin Biochemical Society transactions 43 (2), 162-167, 2015 | 26 | 2015 |
Structure and dynamics of cinnamycin–lipid complexes: Mechanisms of selectivity for phosphatidylethanolamine lipids M Vestergaard, NA Berglund, PC Hsu, C Song, H Koldsø, B Schiøtt, ... ACS omega 4 (20), 18889-18899, 2019 | 19 | 2019 |
Lipid Modulation of a Class B GPCR: Elucidating the Modulatory Role of PI(4,5)P2 Lipids LR Kjølbye, L Sørensen, J Yan, NA Berglund, J Ferkinghoff-Borg, ... Journal of Chemical Information and Modeling 62 (24), 6788-6802, 2022 | 13 | 2022 |
Effect of palmitoylation on the dimer formation of the human dopamine transporter T Zeppelin, KB Pedersen, NA Berglund, X Periole, B Schiøtt Scientific Reports 11 (1), 4164, 2021 | 8 | 2021 |
The effect of cholesterol on membrane-bound islet amyloid polypeptide M Christensen, NA Berglund, B Schiøtt Frontiers in Molecular Biosciences 8, 657946, 2021 | 7 | 2021 |
Effect of cholesterol on the dimerization of C99—A molecular modeling perspective AD Stange, JPC Hsu, LK Ravnkilde, N Berglund, B Schiøtt Biointerphases 16 (3), 2021 | 5 | 2021 |
Interaction of the antimicrobial polymyxin B1 with the inner and outer membranes of E. coli: insights into the mechanisms of membrane disruption NA Berglund, TJ Piggot, S Khalid Biophysical Journal 106 (2), 97a, 2014 | 3 | 2014 |
Extracellular application of the N-methyl-D-aspartate receptor allosteric modulator rapastinel acts remotely to regulate Ca2+ inactivation at an intracellular locus X Zhang, NA Berglund, JS Burgdorf, JE Donello, JR Moskal, PK Stanton NeuroReport 33 (7), 312-319, 2022 | 1 | 2022 |
The Structural Basis for Lipid a Recognition in the CD14 Innate Immune Co-Receptor NA Berglund, DA Holdbrook, S Khalid, PJ Bond Biophysical Journal 108 (2), 350a-351a, 2015 | 1 | 2015 |
Molecular dynamics simulations reveal mechanistic details of polymyxin penetration into both membranes of E. coli S Khalid, NA Berglund, PJ Bond, TJ Piggot Biophysical Journal 108 (2), 549a, 2015 | 1 | 2015 |
Competition for sortilin—a transmembrane love story LM Desdorf, M Overby, NA Berglund, HK Müller, B Schiøtt Biophysical Journal 123 (3), 170a, 2024 | | 2024 |
Exploring the conformational landscape of the insulin receptor using advanced sampling methods AD Stange, NA Berglund, B Schiøtt Biophysical Journal 123 (3), 323a, 2024 | | 2024 |