RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6 E Szenker-Ravi, U Altunoglu, M Leushacke, C Bosso-Lefèvre, M Khatoo, ... Nature 557 (7706), 564-569, 2018 | 158 | 2018 |
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis T Naert, R Colpaert, T Van Nieuwenhuysen, D Dimitrakopoulou, J Leoen, ... Scientific reports 6 (1), 35264, 2016 | 76 | 2016 |
CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs T Naert, K Vleminckx Drug Discovery Today: Technologies 28, 41-52, 2018 | 49 | 2018 |
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis T Van Nieuwenhuysen, T Naert, HT Tran, G Van Imschoot, S Geurs, ... Oncoscience 2 (5), 555, 2015 | 43 | 2015 |
Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos T Naert, D Tulkens, NA Edwards, M Carron, NI Shaidani, M Wlizla, A Boel, ... Scientific reports 10 (1), 14662, 2020 | 36 | 2020 |
TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models T Naert, T Van Nieuwenhuysen, K Vleminckx genesis 55 (1-2), e23005, 2017 | 29 | 2017 |
Homozygous null TBX4 mutations lead to posterior amelia with pelvic and pulmonary hypoplasia A Kariminejad, E Szenker-Ravi, C Lekszas, H Tajsharghi, AR Moslemi, ... The American Journal of Human Genetics 105 (6), 1294-1301, 2019 | 22 | 2019 |
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis T Naert, D Dimitrakopoulou, D Tulkens, S Demuynck, M Carron, ... Oncogene 39 (13), 2692-2706, 2020 | 18 | 2020 |
Deep learning is widely applicable to phenotyping embryonic development and disease T Naert, Ö Çiçek, P Ogar, M Bürgi, NI Shaidani, MM Kaminski, Y Xu, ... Development 148 (21), dev199664, 2021 | 16 | 2021 |
Genotyping of CRISPR/Cas9 Genome Edited Xenopus tropicalis T Naert, K Vleminckx Xenopus: Methods and Protocols, 67-82, 2018 | 12 | 2018 |
Methods for CRISPR/Cas9 Xenopus tropicalis Tissue-Specific Multiplex Genome Engineering T Naert, K Vleminckx Xenopus: Methods and Protocols, 33-54, 2018 | 9 | 2018 |
CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping T Naert, D Tulkens, T Van Nieuwenhuysen, J Przybyl, S Demuynck, ... Proceedings of the National Academy of Sciences 118 (47), e2115116118, 2021 | 8 | 2021 |
Reflective multi-immersion microscope objectives inspired by the Schmidt telescope FF Voigt, AM Reuss, T Naert, S Hildebrand, M Schaettin, AL Hotz, ... Nature Biotechnology 42 (1), 65-71, 2024 | 7 | 2024 |
Cancer Models in Xenopus tropicalis by CRISPR/Cas9 Mediated Knockout of Tumor Suppressors T Naert, K Vleminckx Xenopus: Methods and Protocols, 147-161, 2018 | 5 | 2018 |
CRISPR/Cas9-Mediated Knockout of Rb1 in Xenopus tropicalis T Naert, K Vleminckx The retinoblastoma protein, 177-193, 2018 | 5 | 2018 |
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis. Sci. Rep. 6, 35264 T Naert, R Colpaert, T Van Nieuwenhuysen, D Dimitrakopoulou, J Leoen, ... | 5 | 2016 |
HNF1B alters an evolutionarily conserved nephrogenic program of target genes K Grand, M Stoltz, L Rizzo, R Röck, MM Kaminski, G Salinas, M Getwan, ... Journal of the American Society of Nephrology 34 (3), 412-432, 2023 | 4 | 2023 |
The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples N Vladimirov, FF Voigt, T Naert, GR Araujo, R Cai, AM Reuss, S Zhao, ... bioRxiv, 2023.06. 16.545256, 2023 | 3 | 2023 |
Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for cleared samples N Vladimirov, FF Voigt, T Naert, GR Araujo, R Cai, AM Reuss, S Zhao, ... Nature Communications 15 (1), 2679, 2024 | 2 | 2024 |
Genetic variants in ARHGEF6 cause congenital anomalies of the kidneys and urinary tract in humans, mice, and Frogs V Klämbt, F Buerger, C Wang, T Naert, K Richter, T Nauth, AC Weiss, ... Journal of the American Society of Nephrology 34 (2), 273-290, 2023 | 2 | 2023 |