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Thomas Naert
Thomas Naert
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RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6
E Szenker-Ravi, U Altunoglu, M Leushacke, C Bosso-Lefèvre, M Khatoo, ...
Nature 557 (7706), 564-569, 2018
1582018
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis
T Naert, R Colpaert, T Van Nieuwenhuysen, D Dimitrakopoulou, J Leoen, ...
Scientific reports 6 (1), 35264, 2016
762016
CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs
T Naert, K Vleminckx
Drug Discovery Today: Technologies 28, 41-52, 2018
492018
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis
T Van Nieuwenhuysen, T Naert, HT Tran, G Van Imschoot, S Geurs, ...
Oncoscience 2 (5), 555, 2015
432015
Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos
T Naert, D Tulkens, NA Edwards, M Carron, NI Shaidani, M Wlizla, A Boel, ...
Scientific reports 10 (1), 14662, 2020
362020
TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models
T Naert, T Van Nieuwenhuysen, K Vleminckx
genesis 55 (1-2), e23005, 2017
292017
Homozygous null TBX4 mutations lead to posterior amelia with pelvic and pulmonary hypoplasia
A Kariminejad, E Szenker-Ravi, C Lekszas, H Tajsharghi, AR Moslemi, ...
The American Journal of Human Genetics 105 (6), 1294-1301, 2019
222019
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis
T Naert, D Dimitrakopoulou, D Tulkens, S Demuynck, M Carron, ...
Oncogene 39 (13), 2692-2706, 2020
182020
Deep learning is widely applicable to phenotyping embryonic development and disease
T Naert, Ö Çiçek, P Ogar, M Bürgi, NI Shaidani, MM Kaminski, Y Xu, ...
Development 148 (21), dev199664, 2021
162021
Genotyping of CRISPR/Cas9 Genome Edited Xenopus tropicalis
T Naert, K Vleminckx
Xenopus: Methods and Protocols, 67-82, 2018
122018
Methods for CRISPR/Cas9 Xenopus tropicalis Tissue-Specific Multiplex Genome Engineering
T Naert, K Vleminckx
Xenopus: Methods and Protocols, 33-54, 2018
92018
CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping
T Naert, D Tulkens, T Van Nieuwenhuysen, J Przybyl, S Demuynck, ...
Proceedings of the National Academy of Sciences 118 (47), e2115116118, 2021
82021
Reflective multi-immersion microscope objectives inspired by the Schmidt telescope
FF Voigt, AM Reuss, T Naert, S Hildebrand, M Schaettin, AL Hotz, ...
Nature Biotechnology 42 (1), 65-71, 2024
72024
Cancer Models in Xenopus tropicalis by CRISPR/Cas9 Mediated Knockout of Tumor Suppressors
T Naert, K Vleminckx
Xenopus: Methods and Protocols, 147-161, 2018
52018
CRISPR/Cas9-Mediated Knockout of Rb1 in Xenopus tropicalis
T Naert, K Vleminckx
The retinoblastoma protein, 177-193, 2018
52018
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis. Sci. Rep. 6, 35264
T Naert, R Colpaert, T Van Nieuwenhuysen, D Dimitrakopoulou, J Leoen, ...
52016
HNF1B alters an evolutionarily conserved nephrogenic program of target genes
K Grand, M Stoltz, L Rizzo, R Röck, MM Kaminski, G Salinas, M Getwan, ...
Journal of the American Society of Nephrology 34 (3), 412-432, 2023
42023
The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples
N Vladimirov, FF Voigt, T Naert, GR Araujo, R Cai, AM Reuss, S Zhao, ...
bioRxiv, 2023.06. 16.545256, 2023
32023
Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for cleared samples
N Vladimirov, FF Voigt, T Naert, GR Araujo, R Cai, AM Reuss, S Zhao, ...
Nature Communications 15 (1), 2679, 2024
22024
Genetic variants in ARHGEF6 cause congenital anomalies of the kidneys and urinary tract in humans, mice, and Frogs
V Klämbt, F Buerger, C Wang, T Naert, K Richter, T Nauth, AC Weiss, ...
Journal of the American Society of Nephrology 34 (2), 273-290, 2023
22023
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