Följ
Nicklas Österlund
Nicklas Österlund
Wenner-Gren Fellow, Freie Universität Berlin
Verifierad e-postadress på fu-berlin.de
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Native ion mobility-mass spectrometry reveals the formation of β-barrel shaped amyloid-β hexamers in a membrane-mimicking environment
N Österlund, R Moons, LL Ilag, F Sobott, A Gräslund
Journal of the American Chemical Society 141 (26), 10440-10450, 2019
1042019
Alzheimer’s disease and cigarette smoke components: Effects of nicotine, PAHs, and Cd (II), Cr (III), Pb (II), Pb (IV) ions on amyloid-β peptide aggregation
C Wallin, SB Sholts, N Österlund, J Luo, J Jarvet, PM Roos, L Ilag, ...
Scientific Reports 7 (1), 14423, 2017
882017
Amyloid-β peptide interactions with amphiphilic surfactants: Electrostatic and hydrophobic effects
N Osterlund, YS Kulkarni, AD Misiaszek, C Wallin, DM Krüger, Q Liao, ...
ACS chemical neuroscience 9 (7), 1680-1692, 2018
58*2018
Metal binding to the amyloid-β peptides in the presence of biomembranes: Potential mechanisms of cell toxicity
SKTS Wärmländer, N Österlund, C Wallin, J Wu, J Luo, A Tiiman, J Jarvet, ...
JBIC Journal of Biological Inorganic Chemistry 24, 1189-1196, 2019
532019
Membrane-mimetic systems for biophysical studies of the amyloid-β peptide
N Österlund, J Luo, SKTS Wärmländer, A Gräslund
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (5), 492-501, 2019
442019
Amyloid-β oligomers are captured by the DNAJB6 chaperone: Direct detection of interactions that can prevent primary nucleation
N Österlund, M Lundqvist, LL Ilag, A Gräslund, C Emanuelsson
Journal of Biological Chemistry 295 (24), 8135-8144, 2020
372020
Solvent-assisted paper spray ionization mass spectrometry (SAPSI-MS) for the analysis of biomolecules and biofluids
N Riboni, A Quaranta, HV Motwani, N Österlund, A Gräslund, F Bianchi, ...
Scientific Reports 9 (1), 10296, 2019
192019
Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction
M Kaldmäe, N Österlund, D Lianoudaki, C Sahin, P Bergman, T Nyman, ...
Journal of The American Society for Mass Spectrometry 30 (8), 1385-1388, 2019
192019
A hairpin motif in the amyloid-β peptide is important for formation of disease-related oligomers
M Khaled, I Rönnbäck, LL Ilag, A Gräslund, B Strodel, N Österlund
Journal of the American Chemical Society 145 (33), 18340-18354, 2023
172023
Charge engineering reveals the roles of ionizable side chains in electrospray ionization mass spectrometry
ML Abramsson, C Sahin, JTS Hopper, RMM Branca, J Danielsson, M Xu, ...
JACS Au 1 (12), 2385-2393, 2021
162021
The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments
S Król, N Österlund, F Vosough, J Jarvet, S Wärmländer, A Barth, LL Ilag, ...
Iscience 24 (8), 2021
142021
Identifying the role of co-aggregation of Alzheimer’s amyloid-β with amorphous protein aggregates of non-amyloid proteins
J Wu, N Österlund, H Wang, R Sternke-Hoffmann, H Pupart, LL Ilag, ...
Cell Reports Physical Science 3 (9), 2022
112022
Cell-penetrating peptides with unexpected anti-amyloid properties
N Österlund, SKTS Wärmländer, A Gräslund
Pharmaceutics 14 (4), 823, 2022
102022
Mass spectrometry and machine learning reveal determinants of client recognition by antiamyloid chaperones
N Österlund, T Vosselman, A Leppert, A Gräslund, H Jörnvall, LL Ilag, ...
Molecular & Cellular Proteomics 21 (10), 2022
92022
Structural basis for dityrosine-mediated inhibition of α-synuclein fibrillization
C Sahin, EC Østerlund, N Österlund, J Costeira-Paulo, JN Pedersen, ...
Journal of the American Chemical Society 144 (27), 11949-11954, 2022
82022
Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions
C Sahin, N Österlund, A Leppert, J Johansson, EG Marklund, ...
Chemical Communications 57 (12), 1450-1453, 2021
72021
A “spindle and thread” mechanism unblocks p53 translation by modulating N-terminal disorder
M Kaldmäe, T Vosselman, X Zhong, D Lama, G Chen, M Saluri, ...
Structure 30 (5), 733-742. e7, 2022
62022
Role of hydrophobic residues for the gaseous formation of helical motifs
L Liu, X Dong, Y Liu, N Österlund, A Gräslund, P Carloni, J Li
Chemical communications 55 (35), 5147-5150, 2019
42019
Oligomer Dynamics of LL‐37 Truncated Fragments Probed by α‐Hemolysin Pore and Molecular Simulations
C Liu, A Henning‐Knechtel, N Österlund, J Wu, G Wang, RAO Gräslund, ...
Small 19 (37), 2206232, 2023
32023
The C-terminal domain of the antiamyloid chaperone DNAJB6 binds to amyloid-β peptide fibrils and inhibits secondary nucleation
N Österlund, R Frankel, A Carlsson, D Thacker, M Karlsson, V Matus, ...
Journal of Biological Chemistry 299 (11), 2023
22023
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Artiklar 1–20