Extending healthy life span—from yeast to humans L Fontana, L Partridge, VD Longo science 328 (5976), 321-326, 2010 | 3394 | 2010 |
Fasting: molecular mechanisms and clinical applications VD Longo, MP Mattson Cell metabolism 19 (2), 181-192, 2014 | 1678 | 2014 |
Biodemographic trajectories of longevity JW Vaupel, JR Carey, K Christensen, TE Johnson, AI Yashin, NV Holm, ... Science 280 (5365), 855-860, 1998 | 1328 | 1998 |
Impact of intermittent fasting on health and disease processes MP Mattson, VD Longo, M Harvie Ageing research reviews 39, 46-58, 2017 | 1262 | 2017 |
Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ... Cell metabolism 19 (3), 407-417, 2014 | 1083 | 2014 |
Regulation of longevity and stress resistance by Sch9 in yeast P Fabrizio, F Pozza, SD Pletcher, CM Gendron, VD Longo Science 292 (5515), 288-290, 2001 | 1079 | 2001 |
Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan VD Longo, S Panda Cell metabolism 23 (6), 1048-1059, 2016 | 932 | 2016 |
A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan S Brandhorst, IY Choi, M Wei, CW Cheng, S Sedrakyan, G Navarrete, ... Cell metabolism 22 (1), 86-99, 2015 | 910 | 2015 |
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans J Guevara-Aguirre, P Balasubramanian, M Guevara-Aguirre, M Wei, ... Science translational medicine 3 (70), 70ra13-70ra13, 2011 | 855 | 2011 |
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy C Lee, L Raffaghello, S Brandhorst, FM Safdie, G Bianchi, ... Science translational medicine 4 (124), 124ra27-124ra27, 2012 | 813 | 2012 |
Association of animal and plant protein intake with all-cause and cause-specific mortality M Song, TT Fung, FB Hu, WC Willett, VD Longo, AT Chan, ... JAMA internal medicine 176 (10), 1453-1463, 2016 | 778 | 2016 |
Evolutionary medicine: from dwarf model systems to healthy centenarians? VD Longo, CE Finch Science 299 (5611), 1342-1346, 2003 | 764 | 2003 |
Sirtuins in aging and age-related disease VD Longo, BK Kennedy Cell 126 (2), 257-268, 2006 | 761 | 2006 |
Replicative and chronological aging in Saccharomyces cerevisiae VD Longo, GS Shadel, M Kaeberlein, B Kennedy Cell metabolism 16 (1), 18-31, 2012 | 687 | 2012 |
Superoxide Dismutase Activity Is Essential for Stationary Phase Survival in Saccharomyces cerevisiae: MITOCHONDRIAL PRODUCTION OF TOXIC OXYGEN SPECIES IN VIVO (∗) VD Longo, EB Gralla, JS Valentine Journal of Biological Chemistry 271 (21), 12275-12280, 1996 | 679 | 1996 |
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy L Raffaghello, C Lee, FM Safdie, M Wei, F Madia, G Bianchi, VD Longo Proceedings of the National Academy of Sciences 105 (24), 8215-8220, 2008 | 671 | 2008 |
Meal frequency and timing in health and disease MP Mattson, DB Allison, L Fontana, M Harvie, VD Longo, WJ Malaisse, ... Proceedings of the National Academy of Sciences 111 (47), 16647-16653, 2014 | 641 | 2014 |
The chronological life span of Saccharomyces cerevisiae P Fabrizio, VD Longo Aging cell 2 (2), 73-81, 2003 | 619 | 2003 |
Interventions to slow aging in humans: are we ready? VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ... Aging cell 14 (4), 497-510, 2015 | 618 | 2015 |
SIRT1 is essential for normal cognitive function and synaptic plasticity S Michán, Y Li, MMH Chou, E Parrella, H Ge, JM Long, JS Allard, K Lewis, ... Journal of Neuroscience 30 (29), 9695-9707, 2010 | 581 | 2010 |