| Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast W Fei, G Shui, B Gaeta, X Du, L Kuerschner, P Li, AJ Brown, MR Wenk, ... The Journal of cell biology 180 (3), 473-482, 2008 | 502 | 2008 |
| Cholesterol transport through lysosome-peroxisome membrane contacts BB Chu, YC Liao, W Qi, C Xie, X Du, J Wang, H Yang, HH Miao, BL Li, ... Cell 161 (2), 291-306, 2015 | 385 | 2015 |
| A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking X Du, J Kumar, C Ferguson, TA Schulz, YS Ong, W Hong, WA Prinz, ... Journal of Cell Biology 192 (1), 121-135, 2011 | 339 | 2011 |
| Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis X Du, I Kristiana, J Wong, AJ Brown Molecular biology of the cell 17 (6), 2735-2745, 2006 | 191 | 2006 |
| Human SEIPIN binds anionic phospholipids R Yan, H Qian, I Lukmantara, M Gao, X Du, N Yan, H Yang Developmental cell 47 (2), 248-256. e4, 2018 | 180 | 2018 |
| ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P2) and regulate its level at the plasma membrane R Ghai, X Du, H Wang, J Dong, C Ferguson, AJ Brown, RG Parton, ... Nature communications 8 (1), 757, 2017 | 178 | 2017 |
| SEIPIN regulates lipid droplet expansion and adipocyte development by modulating the activity of glycerol-3-phosphate acyltransferase M Pagac, DE Cooper, Y Qi, IE Lukmantara, HY Mak, Z Wu, Y Tian, Z Liu, ... Cell reports 17 (6), 1546-1559, 2016 | 163 | 2016 |
| ORP2 delivers cholesterol to the plasma membrane in exchange for phosphatidylinositol 4, 5-bisphosphate (PI (4, 5) P2) H Wang, Q Ma, Y Qi, J Dong, X Du, J Rae, J Wang, WF Wu, AJ Brown, ... Molecular cell 73 (3), 458-473. e7, 2019 | 145 | 2019 |
| Structural basis of low-pH-dependent lysosomal cholesterol egress by NPC1 and NPC2 H Qian, X Wu, X Du, X Yao, X Zhao, J Lee, H Yang, N Yan Cell 182 (1), 98-111. e18, 2020 | 124 | 2020 |
| Seipin, adipogenesis and lipid droplets W Fei, X Du, H Yang Trends in Endocrinology & Metabolism 22 (6), 204-210, 2011 | 115 | 2011 |
| TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine YE Li, Y Wang, X Du, T Zhang, HY Mak, SE Hancock, H McEwen, ... Journal of Cell Biology 220 (6), e202103105, 2021 | 114 | 2021 |
| Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis W Fei, H Li, G Shui, TS Kapterian, C Bielby, X Du, AJ Brown, P Li, ... Journal of lipid research 52 (12), 2136-2147, 2011 | 94 | 2011 |
| ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI (4) P on lipid droplets X Du, L Zhou, YC Aw, HY Mak, Y Xu, J Rae, W Wang, A Zadoorian, ... Journal of Cell Biology 219 (1), 2020 | 89 | 2020 |
| Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2 J Dong, X Du, H Wang, J Wang, C Lu, X Chen, Z Zhu, Z Luo, L Yu, ... Nature communications 10 (1), 829, 2019 | 82 | 2019 |
| Structural basis for catalysis and substrate specificity of human ACAT1 H Qian, X Zhao, R Yan, X Yao, S Gao, X Sun, X Du, H Yang, CCL Wong, ... Nature 581 (7808), 333-338, 2020 | 75 | 2020 |
| An essential role of Hrs/Vps27 in endosomal cholesterol trafficking X Du, AS Kazim, AJ Brown, H Yang Cell reports 1 (1), 29-35, 2012 | 63 | 2012 |
| Effects of 25-hydroxycholesterol on cholesterol esterification and sterol regulatory element-binding protein processing are dissociable: implications for cholesterol movement … X Du, YH Pham, AJ Brown Journal of Biological Chemistry 279 (45), 47010-47016, 2004 | 62 | 2004 |
| Lipid droplet biogenesis and functions in health and disease A Zadoorian, X Du, H Yang Nature Reviews Endocrinology 19 (8), 443-459, 2023 | 60 | 2023 |
| Novel mechanisms of intracellular cholesterol transport: oxysterol-binding proteins and membrane contact sites X Du, AJ Brown, H Yang Current opinion in cell biology 35, 37-42, 2015 | 58 | 2015 |
| A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols R Yan, P Cao, W Song, H Qian, X Du, HW Coates, X Zhao, Y Li, S Gao, ... Science 371 (6533), eabb2224, 2021 | 55 | 2021 |
