| Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor TJ Murphy, RW Alexander, KK Griendling, MS Runge, KE Bernstein Nature 351 (6323), 233-236, 1991 | 1556 | 1991 |
| Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor MB Marrero, B Schieffer, WG Paxton, L Heerdt, BC Berk, P Delafontaine, ... Nature 375 (6528), 247-250, 1995 | 923 | 1995 |
| The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 176, S21-S141, 2019 | 742 | 2019 |
| Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. CR Esther Jr, TE Howard, EM Marino, JM Goddard, MR Capecchi, ... Laboratory investigation; a journal of technical methods and pathology 74 (5 …, 1996 | 527 | 1996 |
| The relevance of tissue angiotensin-converting enzyme: manifestations in mechanistic and endpoint data VJ Dzau, K Bernstein, D Celermajer, J Cohen, B Dahlöf, J Deanfield, ... The American journal of cardiology 88 (9), 1-20, 2001 | 519 | 2001 |
| DC isoketal-modified proteins activate T cells and promote hypertension A Kirabo, V Fontana, APC De Faria, R Loperena, CL Galindo, J Wu, ... The Journal of clinical investigation 124 (10), 4642-4656, 2014 | 515 | 2014 |
| The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 178, S27-S156, 2021 | 445 | 2021 |
| ACE and ACE2 activity in diabetic mice J Wysocki, M Ye, MJ Soler, SB Gurley, HD Xiao, KE Bernstein, ... Diabetes 55 (7), 2132-2139, 2006 | 382 | 2006 |
| Nodular (pseudosarcomatous) fasciitis, a nonrecurrent lesion: clinicopathologic study of 134 cases KE Bernstein, R Lattes Cancer 49 (8), 1668-1678, 1982 | 377 | 1982 |
| Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death HD Xiao, S Fuchs, DJ Campbell, W Lewis, SC Dudley Jr, VS Kasi, BD Hoit, ... The American journal of pathology 165 (3), 1019-1032, 2004 | 346 | 2004 |
| The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice. CR Esther, EM Marino, TE Howard, A Machaud, P Corvol, MR Capecchi, ... The Journal of clinical investigation 99 (10), 2375-2385, 1997 | 346 | 1997 |
| A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme KE Bernstein, FS Ong, WLB Blackwell, KH Shah, JF Giani, ... Pharmacological reviews 65 (1), 1-46, 2013 | 337 | 2013 |
| Targeting genes for self-excision in the germ line M Bunting, KE Bernstein, JM Greer, MR Capecchi, KR Thomas Genes & development 13 (12), 1524-1528, 1999 | 304 | 1999 |
| Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction GA Silberman, THM Fan, H Liu, Z Jiao, HD Xiao, JD Lovelock, ... Circulation 121 (4), 519-528, 2010 | 290 | 2010 |
| Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptor MS Ali, PP Sayeski, LB Dirksen, DJ Hayzer, MB Marrero, KE Bernstein Journal of Biological Chemistry 272 (37), 23382-23388, 1997 | 278 | 1997 |
| Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma 1 in vascular smooth muscle cells. MB Marrero, WG Paxton, JL Duff, BC Berk, KE Bernstein Journal of Biological Chemistry 269 (14), 10935-10939, 1994 | 269 | 1994 |
| Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene TE Howard, SY Shai, KG Langford, BM Martin, KE Bernstein Molecular and Cellular Biology, 1990 | 255 | 1990 |
| Mouse angiotensin-converting enzyme is a protein composed of two homologous domains KE Bernstein, BM Martin, AS Edwards, EA Bernstein Journal of Biological Chemistry 264 (20), 11945-11951, 1989 | 244 | 1989 |
| Regulation of steady-state β-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme EA Eckman, SK Adams, FJ Troendle, BA Stodola, MA Kahn, AH Fauq, ... Journal of Biological Chemistry 281 (41), 30471-30478, 2006 | 239 | 2006 |
| Immune activation caused by vascular oxidation promotes fibrosis and hypertension J Wu, MA Saleh, A Kirabo, HA Itani, KRC Montaniel, L Xiao, W Chen, ... The Journal of clinical investigation 126 (1), 50-67, 2016 | 231 | 2016 |
Bradford BerkDistinguished University Professor in Medicine, Neurology, Pathology, and Pharmacology & PhysiologyVerified email at urmc.rochester.edu
