| Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Cancer discovery 5 (12), 1282-1295, 2015 | 1198 | 2015 |
| A new view of transcriptome complexity and regulation through the lens of local splicing variations J Vaquero-Garcia, A Barrera, MR Gazzara, J Gonzalez-Vallinas, ... elife 5, e11752, 2016 | 413 | 2016 |
| Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation NM Martinez, L Agosto, J Qiu, MJ Mallory, MR Gazzara, Y Barash, X Fu, ... Genes & development 29 (19), 2054-2066, 2015 | 74 | 2015 |
| Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19 M Asnani, KE Hayer, AS Naqvi, S Zheng, SY Yang, D Oldridge, F Ibrahim, ... Leukemia 34 (4), 1202-1207, 2020 | 73 | 2020 |
| Integrative deep models for alternative splicing A Jha, MR Gazzara, Y Barash Bioinformatics 33 (14), i274-i282, 2017 | 69 | 2017 |
| Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling MJ Mallory, SJ Allon, J Qiu, MR Gazzara, I Tapescu, NM Martinez, XD Fu, ... Proceedings of the National Academy of Sciences 112 (17), E2139-E2148, 2015 | 69 | 2015 |
| Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing MG Thompson, R Muñoz-Moreno, P Bhat, R Roytenberg, J Lindberg, ... Nature communications 9 (1), 2407, 2018 | 65 | 2018 |
| Aberrant splicing in B-cell acute lymphoblastic leukemia KL Black, AS Naqvi, M Asnani, KE Hayer, SY Yang, E Gillespie, ... Nucleic acids research 46 (21), 11357-11369, 2018 | 61 | 2018 |
| Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes MR Gazzara, MJ Mallory, R Roytenberg, JP Lindberg, A Jha, KW Lynch, ... Genome research 27 (8), 1360-1370, 2017 | 46 | 2017 |
| Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells S Ajith, MR Gazzara, BS Cole, G Shankarling, NM Martinez, MJ Mallory, ... RNA biology 13 (6), 569-581, 2016 | 46 | 2016 |
| Enhanced integrated gradients: improving interpretability of deep learning models using splicing codes as a case study A Jha, J K. Aicher, M R. Gazzara, D Singh, Y Barash Genome biology 21, 1-22, 2020 | 44 | 2020 |
| Mutator dynamics in sexual and asexual experimental populations of yeast Y Raynes, MR Gazzara, PD Sniegowski BMC evolutionary biology 11, 1-7, 2011 | 38 | 2011 |
| RNA binding protein CELF2 regulates signal-induced alternative polyadenylation by competing with enhancers of the polyadenylation machinery R Chatrikhi, MJ Mallory, MR Gazzara, LM Agosto, WS Zhu, AJ Litterman, ... Cell reports 28 (11), 2795-2806. e3, 2019 | 34 | 2019 |
| An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning I Ehrmann, JH Crichton, MR Gazzara, K James, Y Liu, SN Grellscheid, ... Elife 8, e39304, 2019 | 28 | 2019 |
| Deep profiling and custom databases improve detection of proteoforms generated by alternative splicing LM Agosto, MR Gazzara, CM Radens, S Sidoli, J Baeza, BA Garcia, ... Genome research 29 (12), 2046-2055, 2019 | 27 | 2019 |
| Contrasting dynamics of a mutator allele in asexual populations of differing size Y Raynes, MR Gazzara, PD Sniegowski Evolution 66 (7), 2329-2334, 2012 | 27 | 2012 |
| A SLM2 feedback pathway controls cortical network activity and mouse behavior I Ehrmann, MR Gazzara, V Pagliarini, C Dalgliesh, ... Cell reports 17 (12), 3269-3280, 2016 | 23 | 2016 |
| Reciprocal regulation of hnRNP C and CELF2 through translation and transcription tunes splicing activity in T cells MJ Mallory, SP McClory, R Chatrikhi, MR Gazzara, RJ Ontiveros, ... Nucleic acids research 48 (10), 5710-5719, 2020 | 22 | 2020 |
| MAJIQ-SPEL: web-tool to interrogate classical and complex splicing variations from RNA-Seq data CJ Green, MR Gazzara, Y Barash Bioinformatics 34 (2), 300-302, 2018 | 21 | 2018 |
| Analysis of scientific society honors reveals disparities TT Le, DS Himmelstein, AA Hippen, MR Gazzara, CS Greene Cell Systems 12 (9), 900-906. e5, 2021 | 19* | 2021 |
Yoseph BarashAssociate Professor of Genetics and Computer & Information Science, University of PennsylvaniaVerified email at upenn.edu
