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Dra. Victoria Lucia Alonso
Dra. Victoria Lucia Alonso
IBR-CONICET, Facultad de Ciencias Bioquimicas y Farmacéuticas, Universidad Nacional de Rosario
Dirección de correo verificada de ibr-conicet.gov.ar
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Overexpression of Cytoplasmic TcSIR2RP1 and Mitochondrial TcSIR2RP3 Impacts on Trypanosoma cruzi Growth and Cell Invasion
C Ritagliati, VL Alonso, R Manarin, P Cribb, EC Serra
PLoS Neglected Tropical Diseases 9 (4), e0003725, 2015
412015
Lysine acetylation: elucidating the components of an emerging global signaling pathway in trypanosomes
VL Alonso, EC Serra
BioMed Research International 2012, 2012
312012
Effect directed synthesis of a new tyrosinase inhibitor with anti-browning activity
I Cabezudo, IA Ramallo, VL Alonso, RLE Furlan
Food chemistry 341, 128232, 2021
292021
Overexpression of bromodomain factor 3 in Trypanosoma cruzi (TcBDF3) affects differentiation of the parasite and protects it against bromodomain inhibitors
VL Alonso, C Ritagliati, P Cribb, JA Cricco, EC Serra
The FEBS Journal 283 (11), 2051-2066, 2016
262016
A Bioactive Trypanosoma cruzi Bromodomain Inhibitor from Chemically Engineered Extracts
IA Ramallo, VL Alonso, F Rua, E Serra, RLE Furlan
ACS combinatorial science 20 (4), 220-228, 2018
242018
Trypanosoma cruzi bromodomain factor 3 binds acetylated α-tubulin and concentrates in the flagellum during metacyclogenesis
VL Alonso, GV Villanova, C Ritagliati, MC Machado Motta, P Cribb, ...
Eukaryotic Cell 13 (6), 822-831, 2014
232014
Discovery of a biologically active bromodomain inhibitor by target-directed dynamic combinatorial chemistry
P García, VL Alonso, E Serra, AM Escalante, RLE Furlan
ACS medicinal chemistry letters 9 (10), 1002-1006, 2018
202018
Construction of three new Gateway® expression plasmids for Trypanosoma cruzi
VL Alonso, C Ritagliati, P Cribb, EC Serra
Memórias do Instituto Oswaldo Cruz 109, 1081-1085, 2014
202014
Development and in vitro/in vivo evaluation of a novel benznidazole liquid dosage form using a quality‐by‐design approach
HF Santos Souza, D Real, D Leonardi, SC Rocha, V Alonso, E Serra, ...
Tropical Medicine & International Health 22 (12), 1514-1522, 2017
182017
Glycosomal bromodomain factor 1 from Trypanosoma cruzi enhances trypomastigote cell infection and intracellular amastigote growth
C Ritagliati, GV Villanova, VL Alonso, AA Zuma, P Cribb, MCM Motta, ...
Biochemical Journal 473 (1), 73-85, 2016
182016
Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity
LE Tavernelli, MCM Motta, CS Gonçalves, MS da Silva, MC Elias, ...
Scientific Reports 9 (1), 192, 2019
172019
Trypanosoma cruzi High Mobility Group B (TcHMGB) can act as an inflammatory mediator on mammalian cells
P Cribb, V Perdomo, VL Alonso, R Manarin, J Barrios-Payan, ...
PLoS Neglected Tropical Diseases 11 (2), e0005350, 2017
122017
Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease
A Pezza, LE Tavernelli, VL Alonso, V Perdomo, R Gabarro, R Prinjha, ...
ACS Infectious Diseases 8 (5), 1062-1074, 2022
92022
Ultrastructure Expansion Microscopy (U-ExM) in Trypanosoma cruzi: localization of tubulin isoforms and isotypes
VL Alonso
Parasitology Research 121 (10), 3019-3024, 2022
62022
Alpha-Tubulin Acetylation in Trypanosoma cruzi: A Dynamic Instability of Microtubules Is Required for Replication and Cell Cycle Progression
VL Alonso, ME Carloni, CS Gonçalves, G Martinez Peralta, ME Chesta, ...
Frontiers in Cellular and Infection Microbiology 11, 642271, 2021
52021
Aim for the readers! Bromodomains as new targets against Chagas’ disease
VL Alonso, LE Tavernelli, A Pezza, P Cribb, C Ritagliati, E Serra
Current Medicinal Chemistry 26 (36), 6544-6563, 2019
52019
Update on the biological relevance of lysine acetylation as a novel drug target in trypanosomatids
GM Peralta, E Serra, VL Alonso
Current Medicinal Chemistry 29 (20), 3638-3659, 2022
42022
In vitro drug screening against all life cycle stages of trypanosoma cruzi using parasites expressing β-galactosidase
VL Alonso, R Manarin, V Perdomo, E Gulin, E Serra, P Cribb
JoVE (Journal of Visualized Experiments), e63210, 2021
42021
Optimization and biological validation of an in vitro assay using the transfected Dm28c/pLacZ Trypanosoma cruzi strain
JEN Gulin, DM Rocco, V Alonso, P Cribb, J Altcheh, F García-Bournissen
Biology Methods and Protocols 6 (1), bpab004, 2021
22021
Identification of novel Bromodomain inhibitors of Trypanosoma cruzi Bromodomain Factor 2 (TcBDF2) using a fluorescence polarization-base high-throughput assay
EC Serra, L Tavernelli, VL Alonso, I Peña, E Rodríguez Araya, R Manarin, ...
bioRxiv, 2024.02. 16.580721, 2024
2024
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