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Mohamed O. Radwan
Mohamed O. Radwan
Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences
Verified email at kumamoto-u.ac.jp
Title
Cited by
Cited by
Year
Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors
B Sever, MD Altıntop, MO Radwan, A Özdemir, M Otsuka, M Fujita, ...
European journal of medicinal chemistry 182, 111648, 2019
832019
Design, synthesis, and biological evaluation of novel 1, 3, 4-thiadiazole derivatives as potential antitumor agents against chronic myelogenous leukemia: Striking effect of …
MD Altıntop, HI Ciftci, MO Radwan, B Sever, ZA Kaplancıklı, TFS Ali, ...
Molecules 23 (1), 59, 2017
692017
The first pentacyclic triterpenoid gypsogenin derivative exhibiting anti-ABL1 kinase and anti-chronic myelogenous leukemia activities
HI Ciftci, SE Ozturk, TFS Ali, MO Radwan, H Tateishi, R Koga, Z Ocak, ...
Biological and Pharmaceutical Bulletin 41 (4), 570-574, 2018
422018
Design, synthesis, and biological activity of Plastoquinone analogs as a new class of anticancer agents
N Bayrak, H Yıldırım, M Yıldız, MO Radwan, M Otsuka, M Fujita, AF Tuyun, ...
Bioorganic chemistry 92, 103255, 2019
332019
A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group
A Tanaka, MO Radwan, A Hamasaki, A Ejima, E Obata, R Koga, ...
Bioorganic & Medicinal Chemistry Letters 27 (16), 3862-3866, 2017
322017
In vitro and in silico evaluation of anticancer activity of new indole-based 1, 3, 4-oxadiazoles as EGFR and COX-2 inhibitors
B Sever, MD Altıntop, A Özdemir, G Akalın Çiftçi, DE Ellakwa, H Tateishi, ...
Molecules 25 (21), 5190, 2020
292020
Discovery and structure–activity relationship of plastoquinone analogs as anticancer agents against chronic myelogenous leukemia cells
HI Ciftci, N Bayrak, H Yıldırım, M Yıldız, MO Radwan, M Otsuka, M Fujita, ...
Archiv der Pharmazie 352 (12), 1900170, 2019
292019
Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives
HI Abd-Alla, D Souguir, MO Radwan
Archives of pharmacal research, 1-84, 2021
282021
Design, synthesis and biological evaluation of pentacyclic triterpene derivatives: Optimization of anti-ABL kinase activity
H I. Ciftci, M O. Radwan, S E. Ozturk, NG Ulusoy, E Sozer, D E. Ellakwa, ...
Molecules 24 (19), 3535, 2019
282019
Synthesis and biological activity of new 18β-glycyrrhetinic acid derivatives
MO Radwan, MAH Ismail, S El-Mekkawy, NSM Ismail, AG Hanna
Arabian Journal of Chemistry 9 (3), 390-399, 2016
272016
Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib‐sensitive and‐resistant multiple myeloma cells
N Nishimura, MO Radwan, M Amano, S Endo, E Fujii, H Hayashi, S Ueno, ...
Cancer Science 110 (10), 3275-3287, 2019
262019
A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses its Ubiquitination
MF Ryoko Koga, Mohamed O. Radwan,Tomohiko Ejima, Yosuke Kanemaru, Hiroshi ...
ChemMedChem, 2017
262017
Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G
MO Radwan, S Sonoda, T Ejima, A Tanaka, R Koga, Y Okamoto, M Fujita, ...
Bioorganic & medicinal chemistry 24 (18), 4398-4405, 2016
262016
A novel series of chlorinated plastoquinone analogs: Design, synthesis, and evaluation of anticancer activity
N Bayrak, H Yıldırım, M Yıldız, MO Radwan, M Otsuka, M Fujita, HI Ciftci, ...
Chemical Biology & Drug Design 95 (3), 343-354, 2020
252020
Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement
MO Radwan, HI Ciftci, TFS Ali, DE Ellakwa, R Koga, H Tateishi, A Nakata, ...
Molecules 24 (18), 3295, 2019
242019
Anticancer activity of Turkish marine extracts: A purple sponge extract induces apoptosis with multitarget kinase inhibition activity
HI Ciftci, M Can, DE Ellakwa, SC Suner, MA Ibrahim, A Oral, N Sekeroglu, ...
Investigational New Drugs 38, 1326-1333, 2020
232020
New SIRT2 inhibitors: Histidine-based bleomycin spin-off
TFS Ali, HI Ciftci, MO Radwan, R Koga, T Ohsugi, Y Okiyama, T Honma, ...
Bioorganic & Medicinal Chemistry 27 (9), 1767-1775, 2019
222019
EGFR-targeted pentacyclic triterpene analogues for glioma therapy
HI Ciftci, MO Radwan, B Sever, AK Hamdy, S Emirdağ, NG Ulusoy, ...
International Journal of Molecular Sciences 22 (20), 10945, 2021
192021
A new series of antileukemic agents: Design, synthesis, in vitro and in silico evaluation of thiazole-based ABL1 kinase inhibitors
E Zeytün, MD Altıntop, B Sever, A Özdemir, DE Ellakwa, Z Ocak, HI Ciftci, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2021
192021
Minimum structural requirements for inhibitors of the zinc finger protein TRAF6
MO Radwan, R Koga, T Hida, T Ejima, Y Kanemaru, H Tateishi, ...
Bioorganic & Medicinal Chemistry Letters 29 (16), 2162-2167, 2019
192019
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