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Richard Giadone
Richard Giadone
Verified email at fas.harvard.edu
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Year
Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
DV Neel, H Basu, G Gunner, MD Bergstresser, RM Giadone, H Chung, ...
Neuron, 2022.11. 01.513927, 2023
242023
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics
RM Giadone, JD Rosarda, PR Akepati, AC Thomas, B Boldbaatar, ...
Amyloid 25 (3), 148-155, 2018
162018
Rapid implementation of a SARS-CoV-2 diagnostic quantitative real-time PCR test with emergency use authorization at a large academic safety net hospital
K Vanuytsel, A Mithal, RM Giadone, AK Yeung, TM Matte, TW Dowrey, ...
Med 1 (1), 152-157. e3, 2020
152020
Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types
M Ximerakis, KM Holton, RM Giadone, C Ozek, M Saxena, S Santiago, ...
Nature Aging 3 (3), 327-345, 2023
132023
Expression of amyloidogenic transthyretin drives hepatic proteostasis remodeling in an induced pluripotent stem cell model of systemic amyloid disease
RM Giadone, DC Liberti, TM Matte, JD Rosarda, C Torres-Arancivia, ...
Stem Cell Reports 15 (2), 515-528, 2020
102020
Expression levels of lamin A or C are critical to nuclear maturation, functional responses, and gene expression profiles in differentiating mouse neutrophils
K Szymczak, MGH Pelletier, K Malu, AM Barbeau, RM Giadone, ...
ImmunoHorizons 6 (1), 16-35, 2022
52022
qRT-PCR Platforms for Diagnosing and Reporting SARS-CoV-2 Infection in Human Samples
RM Giadone, A Mithal, GJ Miller, TM Matte, AK Yeung, TW Dowrey, ...
STAR protocols 1 (2), 100102, 2020
52020
Mapping cellular response to destabilized transthyretin reveals cell-and amyloidogenic protein-specific signatures
S Ghosh, C Villacorta-Martin, J Lindstrom-Vautrin, D Kenney, CS Golden, ...
Amyloid 30 (4), 379-393, 2023
12023
Patient-specific induced pluripotent stem cells for understanding and assessing novel therapeutics for multisystem transthyretin amyloid disease
RM Giadone, S Ghosh, GJ Murphy
Novel concepts in iPSC disease modeling, 105-122, 2022
12022
Studies of murine neutrophil and macrophage progenitors with ectopic A-type lamins or Sun2 expression implicate the importance of nuclear envelope proteins in myelopoiesis
MGH Pelletier, K Malu, SC Babroudi, RM Giadone, P Gaines
Blood 124 (21), 1401, 2014
12014
Identifying critical roles for the lamin B receptor and additional nuclear envelope proteins in regulating the proliferation and differentiation of myeloid progenitors
KM Malu, HP Shah, MGH Pelletier, RM Giadone, KL Gendreau, ...
12013
Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets
ME Watts, RM Giadone, A Ordureau, KM Holton, JW Harper, LL Rubin
Frontiers in Cellular Neuroscience 17, 1327361, 2024
2024
Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition
CV Edwards, GM Ferri, J Villegas-Galaviz, S Ghosh, P Singh Bawa, ...
bioRxiv, 2024.03. 14.584987, 2024
2024
A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring
TW Dowrey, SF Cranston, N Skvir, Y Lok, B Gould, B Petrowitz, D Villar, ...
bioRxiv, 2024.03. 12.584663, 2024
2024
Abnormal Global Longitudinal Strain Correlates with Amyloidogenic Light Chain-Induced Cardiac Dysfunction via Direct Myocardial Toxicity in Patients without Significant Amyloid …
GM Ferri, J Villegas Galaviz, T Ajayi, R Giadone, GJ Murphy, A Staron, ...
Blood 142 (Supplement 1), 3415-3415, 2023
2023
A Workflow Guide to RNA-Seq Analysis of Chaperone Function and Beyond
KM Holton, RM Giadone, BJ Lang, SK Calderwood
Chaperones: Methods and Protocols, 39-60, 2023
2023
Mapping and Modelling the Molecular Mechanisms That Drive Clonal Plasma Cell-Derived Amyloidogenic Light Chain Induced Cardiotoxicity
CV Edwards, R Giadone, S Ghosh, G Morgan, V Sanchorawala, ...
Blood 140 (Supplement 1), 7127-7128, 2022
2022
Defining cellular and molecular mechanisms of hereditary transthyretin amyloidosis
RM Giadone
Boston University, 2020
2020
An SCF-FBXW7 Ubiquitin Ligase Mediated Feedback Loop Facilitates GATA Factor Switching and Reinforces Commitment to Terminal Erythroid Maturation
A Ghamari, E Jaensch, R Giadone, TE Akie, J Xu, D Bauer, SH Orkin, ...
Blood, The Journal of the American Society of Hematology 124 (21), 245-245, 2014
2014
Sabrina Ghosh, Jolene K. Diedrich, 3 Sandra Pankow, 3 Nicholas Skvir, JC Jean, John R. Yates III, 3 Andrew A. Wilson, Lawreen H. Connors, 2 Darrell N. Kotton, R. Luke Wiseman …
RM Giadone, DC Liberti, TM Matte, JD Rosarda, C Torres-Arancivia
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Articles 1–20