A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly MY Tsai, C Wiese, K Cao, O Martin, P Donovan, J Ruderman, C Prigent, ... Nature cell biology 5 (3), 242-248, 2003 | 426 | 2003 |
Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging M Olive, I Harten, R Mitchell, JK Beers, K Djabali, K Cao, MR Erdos, ... Arteriosclerosis, thrombosis, and vascular biology 30 (11), 2301-2309, 2010 | 423 | 2010 |
Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells K Cao, JJ Graziotto, CD Blair, JR Mazzulli, MR Erdos, D Krainc, FS Collins Science translational medicine 3 (89), 89ra58-89ra58, 2011 | 406 | 2011 |
Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts K Cao, CD Blair, DA Faddah, JE Kieckhaefer, M Olive, MR Erdos, ... The Journal of clinical investigation 121 (7), 2833-2844, 2011 | 383 | 2011 |
Correlated alterations in genome organization, histone methylation, and DNA–lamin A/C interactions in Hutchinson-Gilford progeria syndrome RP McCord, A Nazario-Toole, H Zhang, PS Chines, Y Zhan, MR Erdos, ... Genome research 23 (2), 260-269, 2013 | 345 | 2013 |
In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice LW Koblan, MR Erdos, C Wilson, WA Cabral, JM Levy, ZM Xiong, ... Nature 589 (7843), 608-614, 2021 | 332 | 2021 |
Chromosome alignment and segregation regulated by ubiquitination of survivin QP Vong, K Cao, HY Li, PA Iglesias, Y Zheng Science 310 (5753), 1499-1504, 2005 | 316 | 2005 |
A lamin A protein isoform overexpressed in Hutchinson–Gilford progeria syndrome interferes with mitosis in progeria and normal cells K Cao, BC Capell, MR Erdos, K Djabali, FS Collins Proceedings of the National Academy of Sciences 104 (12), 4949-4954, 2007 | 311 | 2007 |
The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis K Cao, R Nakajima, HH Meyer, Y Zheng Cell 115 (3), 355-367, 2003 | 250 | 2003 |
A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model BC Capell, M Olive, MR Erdos, K Cao, DA Faddah, UL Tavarez, ... Proceedings of the National Academy of Sciences 105 (41), 15902-15907, 2008 | 230 | 2008 |
Characterization and Reconstitution of Drosophila γ-Tubulin Ring Complex Subunits RN Gunawardane, OC Martin, K Cao, L Zhang, K Dej, A Iwamatsu, ... The Journal of cell biology 151 (7), 1513-1524, 2000 | 142 | 2000 |
Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria ZM Xiong, JY Choi, K Wang, H Zhang, Z Tariq, DI Wu, E Ko, C LaDana, ... Aging cell 15 (2), 279-290, 2016 | 124 | 2016 |
A tissue engineered blood vessel model of Hutchinson-Gilford progeria syndrome using human iPSC-derived smooth muscle cells L Atchison, H Zhang, K Cao, GA Truskey Scientific reports 7 (1), 8168, 2017 | 107 | 2017 |
Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly (ADP-ribose) polymerase 1 H Zhang, ZM Xiong, K Cao Proceedings of the National Academy of Sciences 111 (22), E2261-E2270, 2014 | 101 | 2014 |
Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: implications for normal aging and age-dependent neurodegenerative disorders JJ Graziotto, K Cao, FS Collins, D Krainc Autophagy 8 (1), 147-151, 2012 | 101 | 2012 |
Anti-aging potentials of methylene blue for human skin longevity ZM Xiong, M O’Donovan, L Sun, JY Choi, M Ren, K Cao Scientific reports 7 (1), 2475, 2017 | 98 | 2017 |
Mouse models of laminopathies H Zhang, JE Kieckhaefer, K Cao Aging cell 12 (1), 2-10, 2013 | 89 | 2013 |
Comprehensive map of age-associated splicing changes across human tissues and their contributions to age-associated diseases K Wang, D Wu, H Zhang, A Das, M Basu, J Malin, K Cao, S Hannenhalli Scientific reports 8 (1), 10929, 2018 | 64 | 2018 |
Automated image analysis of nuclear shape: What can we learn from a prematurely aged cell? MK Driscoll, JL Albanese, ZM Xiong, M Mailman, W Losert, K Cao Aging (Albany NY) 4 (2), 119, 2012 | 64 | 2012 |
An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells ZM Xiong, C LaDana, D Wu, K Cao Aging (Albany NY) 5 (4), 288, 2013 | 62 | 2013 |