IL-33 is more potent than IL-25 in provoking IL-13–producing nuocytes (type 2 innate lymphoid cells) and airway contraction JL Barlow, S Peel, J Fox, V Panova, CS Hardman, A Camelo, C Bucks, ... Journal of allergy and clinical immunology 132 (4), 933-941, 2013 | 462 | 2013 |
ORAI and store-operated calcium influx in human airway smooth muscle cells SE Peel, B Liu, IP Hall American journal of respiratory cell and molecular biology 38 (6), 744-749, 2008 | 148 | 2008 |
Pharmacology of the ATM inhibitor AZD0156: potentiation of irradiation and olaparib responses preclinically LC Riches, AG Trinidad, G Hughes, GN Jones, AM Hughes, ... Molecular cancer therapeutics 19 (1), 13-25, 2020 | 130 | 2020 |
A key role for STIM1 in store operated calcium channel activation in airway smooth muscle SE Peel, B Liu, IP Hall Respiratory research 7, 1-8, 2006 | 129 | 2006 |
Introducing an automated high content confocal imaging approach for Organs-on-Chips S Peel, AM Corrigan, B Ehrhardt, KJ Jang, P Caetano-Pinto, M Boeckeler, ... Lab on a Chip 19 (3), 410-421, 2019 | 95 | 2019 |
Recognition of the major cat allergen Fel d 1 through the cysteine-rich domain of the mannose receptor determines its allergenicity M Emara, PJ Royer, Z Abbas, HF Sewell, GG Mohamed, S Singh, S Peel, ... Journal of Biological Chemistry 286 (15), 13033-13040, 2011 | 91 | 2011 |
Endocytic profiling of cancer cell models reveals critical factors influencing LNP-mediated mRNA delivery and protein expression EJ Sayers, SE Peel, A Schantz, RM England, M Beano, SM Bates, ... Molecular Therapy 27 (11), 1950-1962, 2019 | 80 | 2019 |
Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation B Liu, SE Peel, J Fox, IP Hall Respiratory research 11, 1-12, 2010 | 57 | 2010 |
A biomechanical model of agonist-initiated contraction in the asthmatic airway BS Brook, SE Peel, IP Hall, AZ Politi, J Sneyd, Y Bai, MJ Sanderson, ... Respiratory physiology & neurobiology 170 (1), 44-58, 2010 | 54 | 2010 |
Nickel induces intracellular calcium mobilization and pathophysiological responses in human cultured airway epithelial cells J Cortijo, J Milara, M Mata, E Donet, N Gavara, SE Peel, IP Hall, ... Chemico-biological interactions 183 (1), 25-33, 2010 | 52 | 2010 |
Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells in Phenotypic Screening: A Transforming Growth Factor-β Type 1 Receptor Kinase … L Drowley, C Koonce, S Peel, A Jonebring, AT Plowright, SJ Kattman, ... Stem cells translational medicine 5 (2), 164-174, 2016 | 48 | 2016 |
Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system T Kostrzewski, S Snow, AL Battle, S Peel, Z Ahmad, J Basak, M Surakala, ... Communications Biology 4 (1), 1080, 2021 | 31 | 2021 |
Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach L Drowley, J McPheat, A Nordqvist, S Peel, U Karlsson, S Martinsson, ... Stem cells translational medicine 9 (1), 47-60, 2020 | 24 | 2020 |
Imaging microphysiological systems: A review S Peel, M Jackman American Journal of Physiology-Cell Physiology 320 (5), C669-C680, 2021 | 18 | 2021 |
Arrayed CRISPR screening identifies novel targets that enhance the productive delivery of mRNA by MC3-based lipid nanoparticles D Ross-Thriepland, A Bornot, L Butler, A Desai, H Jaiswal, S Peel, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (6), 605-617, 2020 | 18 | 2020 |
Understanding intracellular biology to improve mRNA delivery by lipid nanoparticles MR Hunter, L Cui, BT Porebski, S Pereira, S Sonzini, U Odunze, P Iyer, ... Small methods 7 (9), 2201695, 2023 | 14 | 2023 |
Practical segmentation of nuclei in brightfield cell images with neural networks trained on fluorescently labelled samples D Fishman, SO Salumaa, D Majoral, T Laasfeld, S Peel, J Wildenhain, ... Journal of Microscopy 284 (1), 12-24, 2021 | 12 | 2021 |
Salmeterol and cytokines modulate inositol-phosphate signalling in Human airway smooth muscle cells via regulation at the receptor locus N Smith, CA Browning, N Duroudier, C Stewart, S Peel, C Swan, IP Hall, ... Respiratory Research 8, 1-15, 2007 | 12 | 2007 |
Nuclear fascin regulates cancer cell survival CD Lawson, S Peel, A Jayo, A Corrigan, P Iyer, MB Dalrymple, RJ Marsh, ... Elife 11, e79283, 2022 | 10 | 2022 |
Delivering robust candidates to the drug pipeline through computational analysis of arrayed CRISPR screens ML Guerriero, A Corrigan, A Bornot, M Firth, P O’Shea, D Ross-Thriepland, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (6), 646-654, 2020 | 9 | 2020 |