| Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis M Sun, W Wu, L Chen, W Yang, X Huang, C Ma, F Chen, Y Xiao, Y Zhao, ... Nature communications 9 (1), 3555, 2018 | 442 | 2018 |
| Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites H Guo, WC Chou, Y Lai, K Liang, JW Tam, WJ Brickey, L Chen, ... Science 370 (6516), eaay9097, 2020 | 305 | 2020 |
| Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt JE Wilson, AS Petrucelli, L Chen, AA Koblansky, AD Truax, Y Oyama, ... Nature medicine 21 (8), 906-913, 2015 | 270 | 2015 |
| NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth L Chen, JE Wilson, MJ Koenigsknecht, WC Chou, SA Montgomery, ... Nature immunology 18 (5), 541-551, 2017 | 251 | 2017 |
| Dual base editor catalyzes both cytosine and adenine base conversions in human cells X Zhang, B Zhu, L Chen, L Xie, W Yu, Y Wang, L Li, S Yin, L Yang, H Hu, ... Nature biotechnology 38 (7), 856-860, 2020 | 211 | 2020 |
| Cell-free circulating miRNA biomarkers in cancer MH Mo, L Chen, Y Fu, W Wang, SW Fu Journal of Cancer 3, 432, 2012 | 198 | 2012 |
| The inhibitory innate immune sensor NLRP12 maintains a threshold against obesity by regulating gut microbiota homeostasis AD Truax, L Chen, JW Tam, N Cheng, H Guo, AA Koblansky, WC Chou, ... Cell host & microbe 24 (3), 364-378. e6, 2018 | 189 | 2018 |
| TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway Y Liu, S Tao, L Liao, Y Li, H Li, Z Li, L Lin, X Wan, X Yang, L Chen Nature communications 11 (1), 348, 2020 | 170 | 2020 |
| miRNA biomarkers in breast cancer detection and management SW Fu, L Chen, Y Man Journal of Cancer 2, 116, 2011 | 151 | 2011 |
| Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components R Liu, AD Truax, L Chen, P Hu, Z Li, J Chen, C Song, L Chen, JPY Ting Oncotarget 6 (32), 33456, 2015 | 144 | 2015 |
| Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL-10–producing regulatory B cells Y Mishima, A Oka, B Liu, JW Herzog, CS Eun, TJ Fan, E Bulik-Sullivan, ... The Journal of clinical investigation 129 (9), 3702-3716, 2019 | 141 | 2019 |
| Microbiota metabolite butyrate differentially regulates Th1 and Th17 cells’ differentiation and function in induction of colitis L Chen, M Sun, W Wu, W Yang, X Huang, Y Xiao, C Ma, L Xu, S Yao, ... Inflammatory bowel diseases 25 (9), 1450-1461, 2019 | 128 | 2019 |
| Role of deregulated microRNAs in breast cancer progression using FFPE tissue L Chen, Y Li, Y Fu, J Peng, MH Mo, M Stamatakos, CB Teal, RF Brem, ... PloS one 8 (1), e54213, 2013 | 117 | 2013 |
| Enhanced degradation of misfolded proteins promotes tumorigenesis L Chen, MD Brewer, L Guo, R Wang, P Jiang, X Yang Cell reports 18 (13), 3143-3154, 2017 | 102 | 2017 |
| Role of β-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes SD Narasipura, LJ Henderson, SW Fu, L Chen, F Kashanchi, L Al-Harthi Journal of virology 86 (4), 1911-1921, 2012 | 100 | 2012 |
| AIM2 in regulatory T cells restrains autoimmune diseases WC Chou, Z Guo, H Guo, L Chen, G Zhang, K Liang, L Xie, X Tan, ... Nature 591 (7849), 300-305, 2021 | 99 | 2021 |
| miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer X Tan, Y Fu, L Chen, W Lee, Y Lai, K Rezaei, S Tabbara, P Latham, ... Oncotarget 7 (1), 293, 2016 | 97 | 2016 |
| Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain X Zhang, L Chen, B Zhu, L Wang, C Chen, M Hong, Y Huang, H Li, H Han, ... Nature cell biology 22 (6), 740-750, 2020 | 89 | 2020 |
| NLRP12 regulates anti-viral RIG-I activation via interaction with TRIM25 ST Chen, L Chen, DSC Lin, SY Chen, YP Tsao, H Guo, FJ Li, WT Tseng, ... Cell host & microbe 25 (4), 602-616. e7, 2019 | 81 | 2019 |
| Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase X Shao, Z Ding, W Zhou, Y Li, Z Li, H Cui, X Lin, G Cao, B Cheng, H Sun, ... Nature Nanotechnology 16 (10), 1150-1160, 2021 | 71 | 2021 |
