| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13150* | 2021 |
| Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. E Bonfoco, D Krainc, M Ankarcrona, P Nicotera, SA Lipton Proceedings of the National Academy of Sciences 92 (16), 7162-7166, 1995 | 2671 | 1995 |
| Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice J Lin, PH Wu, PT Tarr, KS Lindenberg, J St-Pierre, C Zhang, VK Mootha, ... Cell 119 (1), 121-135, 2004 | 1421 | 2004 |
| Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies JR Mazzulli, YH Xu, Y Sun, AL Knight, PJ McLean, GA Caldwell, ... Cell 146 (1), 37-52, 2011 | 1396 | 2011 |
| Transcriptional repression of PGC-1α by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration L Cui, H Jeong, F Borovecki, CN Parkhurst, N Tanese, D Krainc Cell 127 (1), 59-69, 2006 | 1207 | 2006 |
| A call for transparent reporting to optimize the predictive value of preclinical research SC Landis, SG Amara, K Asadullah, CP Austin, R Blumenstein, ... Nature 490 (7419), 187-191, 2012 | 1173 | 2012 |
| Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease AW Dunah, H Jeong, A Griffin, YM Kim, DG Standaert, SM Hersch, ... Science 296 (5576), 2238-2243, 2002 | 850 | 2002 |
| Human iPSC-based modeling of late-onset disease via progerin-induced aging JD Miller, YM Ganat, S Kishinevsky, RL Bowman, B Liu, EY Tu, ... Cell stem cell 13 (6), 691-705, 2013 | 780 | 2013 |
| Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals C Handschin, S Chin, P Li, F Liu, E Maratos-Flier, NK LeBrasseur, Z Yan, ... Journal of Biological Chemistry 282 (41), 30014-30021, 2007 | 740 | 2007 |
| Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease LF Burbulla, P Song, JR Mazzulli, E Zampese, YC Wong, S Jeon, ... Science 357 (6357), 1255-1261, 2017 | 724 | 2017 |
| α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies YC Wong, D Krainc Nature medicine 23 (2), 1-13, 2017 | 679 | 2017 |
| Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration P Weydt, VV Pineda, AE Torrence, RT Libby, TF Satterfield, ... Cell metabolism 4 (5), 349-362, 2006 | 667 | 2006 |
| Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis YC Wong, D Ysselstein, D Krainc Nature 554 (7692), 382-386, 2018 | 650 | 2018 |
| Classification and phylogeny of the MADS-box multigene family suggest defined roles of MADS-box gene subfamilies in the morphological evolution of eukaryotes G Theißen, JT Kim, H Saedler Journal of Molecular Evolution 43, 484-516, 1996 | 566 | 1996 |
| Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease O Cooper, H Seo, S Andrabi, C Guardia-Laguarta, J Graziotto, ... Science translational medicine 4 (141), 141ra90-141ra90, 2012 | 557 | 2012 |
| Identification and rescue of α-synuclein toxicity in Parkinson patient–derived neurons CY Chung, V Khurana, PK Auluck, DF Tardiff, JR Mazzulli, F Soldner, ... Science 342 (6161), 983-987, 2013 | 512 | 2013 |
| Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease F Borovecki, L Lovrecic, J Zhou, H Jeong, F Then, HD Rosas, SM Hersch, ... Proceedings of the National Academy of Sciences 102 (31), 11023-11028, 2005 | 497 | 2005 |
| Acetylation targets mutant huntingtin to autophagosomes for degradation H Jeong, F Then, TJ Melia, JR Mazzulli, L Cui, JN Savas, C Voisine, ... Cell 137 (1), 60-72, 2009 | 482 | 2009 |
| Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect G Esposito, BS Jaiswal, F Xie, MAM Krajnc-Franken, TJAA Robben, ... Proceedings of the National Academy of Sciences 101 (9), 2993-2998, 2004 | 475 | 2004 |
| A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies MA Nalls, R Duran, G Lopez, M Kurzawa-Akanbi, IG McKeith, ... JAMA neurology 70 (6), 727-735, 2013 | 474 | 2013 |
Joe MazzulliNorthwestern NeurologyVerified email at northwestern.edu
