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Robert C.C. Mercer
Robert C.C. Mercer
Instructor, Boston University Chobanian & Avedisian School of Medicine
Verified email at bu.edu
Title
Cited by
Cited by
Year
Prions activate a p38 MAPK synaptotoxic signaling pathway
C Fang, B Wu, NTT Le, T Imberdis, RCC Mercer, DA Harris
PLoS pathogens 14 (9), e1007283, 2018
622018
The prion protein modulates A-type K+ currents mediated by Kv4. 2 complexes through dipeptidyl aminopeptidase-like protein 6
RCC Mercer, L Ma, JC Watts, R Strome, S Wohlgemuth, J Yang, ...
Journal of Biological Chemistry 288 (52), 37241-37255, 2013
402013
Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation
A Lau, A McDonald, N Daude, CE Mays, ED Walter, R Aglietti, ...
EMBO molecular medicine 7 (3), 339-356, 2015
372015
Endoproteolytic processing of the mammalian prion glycoprotein family
CE Mays, J Coomaraswamy, JC Watts, J Yang, KWS Ko, B Strome, ...
The FEBS journal 281 (3), 862-876, 2014
292014
A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS …
RCC Mercer, N Daude, L Dorosh, ZL Fu, CE Mays, H Gapeshina, ...
PLoS pathogens 14 (1), e1006826, 2018
232018
Mechanisms of prion-induced toxicity
RCC Mercer, DA Harris
Cell and Tissue Research 392 (1), 81-96, 2023
112023
Identification of anti-prion drugs and targets using toxicity-based assays
RCC Mercer, DA Harris
Current opinion in pharmacology 44, 20-27, 2019
82019
Prion diseases
RCC Mercer, AJ McDonald, E Bove-Fenderson, C Fang, B Wu, DA Harris
The Molecular and Cellular Basis of Neurodegenerative Diseases, 23-56, 2018
72018
Vertebrate slow skeletal muscle actin—conservation, distribution and conformational flexibility
RCC Mercer, WAKA Mudalige, TO Ige, DH Heeley
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (10), 1253-1260, 2011
52011
Prion Proteins and the Alzheimer Disease A beta Amyloid Cascade
D Westaway, K Alier, D Vergote, D MacTavish, R Mercer, W Fu, J Yang, ...
Prion 5, 1-2, 2011
32011
P4‐506: ROLE OF P38α MAP KINASE IN AMYLOID‐β DERIVED DIFFUSIBLE LIGAND (ADDL) INDUCED DENDRITIC SPINE LOSS IN HIPPOCAMPAL NEURONS
L Amin, N Le, RCC Mercer, U Germann, J Alam, DA Harris
Alzheimer's & Dementia 15, P1507-P1507, 2019
22019
Slow skeletal muscle actin
RCC Mercer, WAKA Mudalige, DH Heeley
Biophysical Journal 96 (3), 124a, 2009
12009
Sigma receptor ligands are potent anti-prion compounds that act independently of sigma receptor binding
RCC Mercer, NTT Le, MCQ Houser, AB Beeler, DA Harris
bioRxiv, 2023.11. 28.569035, 2023
2023
NMDA receptor misalignment in iPSC-derived neurons from a multi-generational family with inherited Creutzfeldt-Jakob disease
NTT Le, RCC Mercer, AD Gojanovich, A Anane, S Park, B Wu, PS Bawa, ...
bioRxiv, 2022.05. 20.491674, 2022
2022
Identification of Receptors for TDP-43 That Mediate Cellular Uptake and Neurotoxicity
RC Mercer, BOSTON UNIV MEDICAL CAMPUS MA
2022
Signalling pathways underlying prion neurotoxicity
NT Le, RC Mercer, DA Harris
PRION 13, 17-17, 2019
2019
'Novel compounds for the treatment of prion disease'
RCC Mercer, NTT Le, D Fraser, A Beeler, DA Harris
PRION 13, 128-128, 2019
2019
Propagation of Misfolded Proteins in Neurodegeneration: Insights and Cautions from the Study of Prion Disease Prototypes
RCC Mercer, N Daude, D Westaway
Protein Folding Disorders Of The Central Nervous System, 203, 2017
2017
The Prion Protein: Modulation of Potassium Channels and a Novel Mouse Model of a Disease-Causing Hydrophobic Domain Insertion Mutation
RCC Mercer
2016
Transgenic mouse expressing a novel Gerstmann-Straussler-Scheinker disease Prnp allele with a partial duplication of the PrP hydrophobic domain
RCC Mercer, CE Mays, N Daude, H Gapeshina, SL Wohlgemuth, J Yang, ...
PRION 8, 114-115, 2014
2014
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Articles 1–20