| Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors Y Uchida, S Ohtsuki, Y Katsukura, C Ikeda, T Suzuki, J Kamiie, T Terasaki Journal of neurochemistry 117 (2), 333-345, 2011 | 852 | 2011 |
| Contribution of carrier-mediated transport systems to the blood–brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and … S Ohtsuki, T Terasaki Pharmaceutical research 24, 1745-1758, 2007 | 553 | 2007 |
| Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide … J Kamiie, S Ohtsuki, R Iwase, K Ohmine, Y Katsukura, K Yanai, Y Sekine, ... Pharmaceutical research 25, 1469-1483, 2008 | 550 | 2008 |
| Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual … S Ohtsuki, O Schaefer, H Kawakami, T Inoue, S Liehner, A Saito, ... Drug metabolism and Disposition 40 (1), 83-92, 2012 | 499 | 2012 |
| In vitro models for the blood–brain barrier P Garberg, M Ball, N Borg, R Cecchelli, L Fenart, RD Hurst, T Lindmark, ... Toxicology in vitro 19 (3), 299-334, 2005 | 494 | 2005 |
| A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro S Hori, S Ohtsuki, K Hosoya, E Nakashima, T Terasaki Journal of neurochemistry 89 (2), 503-513, 2004 | 406 | 2004 |
| Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels R Shawahna, Y Uchida, X Decleves, S Ohtsuki, S Yousif, S Dauchy, ... Molecular pharmaceutics 8 (4), 1332-1341, 2011 | 395 | 2011 |
| P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells A Tsuji, T Terasaki, Y Takabatake, Y Tenda, I Tamai, T Yamashima, ... Life sciences 51 (18), 1427-1437, 1992 | 374 | 1992 |
| Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy EC Leal, A Manivannan, KI Hosoya, T Terasaki, J Cunha-Vaz, ... Investigative ophthalmology & visual science 48 (11), 5257-5265, 2007 | 302 | 2007 |
| Brain efflux index as a novel method of analyzing efflux transport at the blood-brain barrier. A Kakee, T Terasaki, Y Sugiyama Journal of Pharmacology and Experimental Therapeutics 277 (3), 1550-1559, 1996 | 277 | 1996 |
| Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions L Perrone, TS Devi, K Hosoya, T Terasaki, LP Singh Journal of cellular physiology 221 (1), 262-272, 2009 | 268 | 2009 |
| In Vivo and in Vitro Blood–Brain Barrier Transport of 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors A Saheki, T Terasaki, I Tamai, A Tsuji Pharmaceutical research 11, 305-311, 1994 | 266 | 1994 |
| Quantitative membrane protein expression at the blood–brain barrier of adult and younger cynomolgus monkeys K Ito, Y Uchida, S Ohtsuki, S Aizawa, H Kawakami, Y Katsukura, J Kamiie, ... Journal of pharmaceutical sciences 100 (9), 3939-3950, 2011 | 245 | 2011 |
| Quantitative atlas of blood–brain barrier transporters, receptors, and tight junction proteins in rats and common marmoset Y Hoshi, Y Uchida, M Tachikawa, T Inoue, S Ohtsuki, T Terasaki Journal of pharmaceutical sciences 102 (9), 3343-3355, 2013 | 243 | 2013 |
| Role of blood–brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from … S Ohtsuki, H Asaba, H Takanaga, T Deguchi, K Hosoya, M Otagiri, ... Journal of neurochemistry 83 (1), 57-66, 2002 | 237 | 2002 |
| Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 … S Ohtsuki, C Ikeda, Y Uchida, Y Sakamoto, F Miller, F Glacial, X Decleves, ... Molecular pharmaceutics 10 (1), 289-296, 2013 | 232 | 2013 |
| The blood–brain barrier creatine transporter is a major pathway for supplying creatine to the brain S Ohtsuki, M Tachikawa, H Takanaga, H Shimizu, M Watanabe, K Hosoya, ... Journal of Cerebral Blood Flow & Metabolism 22 (11), 1327-1335, 2002 | 219 | 2002 |
| A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters … Y Uchida, M Tachikawa, W Obuchi, Y Hoshi, Y Tomioka, S Ohtsuki, ... Fluids and Barriers of the CNS 10, 1-22, 2013 | 218 | 2013 |
| Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein A Tsuji, I Tamai, A Sakata, Y Tenda, T Terasaki Biochemical pharmacology 46 (6), 1096-1099, 1993 | 218 | 1993 |
| New approaches to in vitro models of blood–brain barrier drug transport T Terasaki, S Ohtsuki, S Hori, H Takanaga, E Nakashima, K Hosoya Drug discovery today 8 (20), 944-954, 2003 | 204 | 2003 |
Sumio OhtsukiFaculty of Life Sciences, Kumamoto UniversityVerified email at kumamoto-u.ac.jp
