An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension J Kim, Y Kang, Y Kojima, JK Lighthouse, X Hu, MA Aldred, DL McLean, ... Nature medicine 19 (1), 74-82, 2013 | 395 | 2013 |
Transcriptional control of cardiac fibroblast plasticity JK Lighthouse, EM Small Journal of molecular and cellular cardiology 91, 52-60, 2016 | 142 | 2016 |
Recapitulation of developing artery muscularization in pulmonary hypertension AQ Sheikh, JK Lighthouse, DM Greif Cell reports 6 (5), 809-817, 2014 | 125 | 2014 |
Sacubitril/valsartan decreases cardiac fibrosis in left ventricle pressure overload by restoring PKG signaling in cardiac fibroblasts RM Burke, JK Lighthouse, DM Mickelsen, EM Small Circulation: Heart Failure 12 (4), e005565, 2019 | 119 | 2019 |
Radial construction of an arterial wall DM Greif, M Kumar, JK Lighthouse, J Hum, A An, L Ding, K Red-Horse, ... Developmental cell 23 (3), 482-493, 2012 | 96 | 2012 |
A novel role of cyclic nucleotide phosphodiesterase 10A in pathological cardiac remodeling and dysfunction S Chen, Y Zhang, JK Lighthouse, DM Mickelsen, J Wu, P Yao, EM Small, ... Circulation 141 (3), 217-233, 2020 | 61 | 2020 |
Development and pathologies of the arterial wall SB Seidelmann, JK Lighthouse, DM Greif Cellular and molecular life sciences 71, 1977-1999, 2014 | 47 | 2014 |
Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure RM Burke, JK Lighthouse, P Quijada, RA Dirkx Jr, A Rosenberg, ... Proceedings of the National Academy of Sciences 115 (15), E3436-E3445, 2018 | 36 | 2018 |
Exercise promotes a cardioprotective gene program in resident cardiac fibroblasts JK Lighthouse, RM Burke, LS Velasquez, RA Dirkx Jr, ... JCI insight 4 (1), 2019 | 35 | 2019 |
MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm JK Lighthouse, L Zhang, JC Hsieh, T Rosenquist, BC Holdener Developmental Dynamics 240 (3), 577-588, 2011 | 29 | 2011 |
Pre-existing fibroblasts of epicardial origin are the primary source of pathological fibrosis in cardiac ischemia and aging P Quijada, A Misra, LS Velasquez, RM Burke, JK Lighthouse, ... Journal of molecular and cellular cardiology 129, 92-104, 2019 | 22 | 2019 |
Prevention of fibrosis and pathological cardiac remodeling by salinomycin RM Burke, RA Dirkx Jr, P Quijada, JK Lighthouse, A Mohan, M O’Brien, ... Circulation research 128 (11), 1663-1678, 2021 | 16 | 2021 |
Protective transcriptional mechanisms in cardiomyocytes and cardiac fibroblasts CS Brand, JK Lighthouse, MA Trembley Journal of molecular and cellular cardiology 132, 1-12, 2019 | 13 | 2019 |
The structure of MESD45–184 brings light into the mechanism of LDLR family folding C Köhler, JK Lighthouse, T Werther, OM Andersen, A Diehl, P Schmieder, ... Structure 19 (3), 337-348, 2011 | 11 | 2011 |
p53 Regulates the extent of fibroblast proliferation and fibrosis in left ventricle pressure overload X Liu, RM Burke, JK Lighthouse, CD Baker, RA Dirkx Jr, B Kang, ... Circulation research 133 (3), 271-287, 2023 | 9 | 2023 |
Development of a Conditional Mesd (Mesoderm Development) Allele for Functional Analysis of the Low-Density Lipoprotein Receptor-Related Family in Defined … AV Taibi, JK Lighthouse, RC Grady, KR Shroyer, BC Holdener Plos one 8 (10), e75782, 2013 | 1 | 2013 |
Cell-Based Phenotypic Screen for Antifibrotic Compounds Targets Eicosanoid Metabolism JK Lighthouse, EM Small Circulation research 132 (1), 30-33, 2023 | | 2023 |
P53 Temporally Regulates the Myofibroblast Activation Response in Pressure Overload RM Burke, J Lighthouse, PJ Quijada, R Dirkx, EM Small Circulation Research 127 (Suppl_1), A435-A435, 2020 | | 2020 |
Fzd2 Inhibits Yap and Prevents Cell-Cycle Reentry in Adult Murine Cardiomyocytes J Bisson, PJ Quijada, J Lighthouse, EM Small, ED Cohen Circulation 140 (Suppl_1), A16022-A16022, 2019 | | 2019 |
Epicardium-derived resident mesenchymal cells promote cardiac fibrosis P Quijada, M Trembley, A Misra, R Burke, J Lighthouse, L Velasquez, ... Journal of Molecular and Cellular Cardiology 124, 102, 2018 | | 2018 |