| EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma A Gorthi, JC Romero, E Loranc, L Cao, LA Lawrence, E Goodale, ... Nature 555 (7696), 387-391, 2018 | 269 | 2018 |
| Predicting drug response of tumors from integrated genomic profiles by deep neural networks YC Chiu, HIH Chen, T Zhang, S Zhang, A Gorthi, LJ Wang, Y Huang, ... BMC medical genomics 12, 143-155, 2019 | 211 | 2019 |
| Nucleolar RNA polymerase II drives ribosome biogenesis KJ Abraham, N Khosraviani, JNY Chan, A Gorthi, A Samman, DY Zhao, ... Nature 585 (7824), 298-302, 2020 | 155 | 2020 |
| The molecular landscape of ETMR at diagnosis and relapse S Lambo, SN Gröbner, T Rausch, SM Waszak, C Schmidt, A Gorthi, ... Nature 576 (7786), 274-280, 2019 | 118 | 2019 |
| Alkylating agent–induced NRF2 blocks endoplasmic reticulum stress–mediated apoptosis via control of glutathione pools and protein thiol homeostasis A Zanotto-Filho, VP Masamsetti, E Loranc, SS Tonapi, A Gorthi, X Bernard, ... Molecular cancer therapeutics 15 (12), 3000-3014, 2016 | 62 | 2016 |
| Deep learning of pharmacogenomics resources: moving towards precision oncology YC Chiu, HIH Chen, A Gorthi, M Mostavi, S Zheng, Y Huang, Y Chen Briefings in bioinformatics 21 (6), 2066-2083, 2020 | 60 | 2020 |
| Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates P Countryman, Y Fan, A Gorthi, H Pan, J Strickland, P Kaur, X Wang, J Lin, ... Journal of Biological Chemistry 293 (3), 1054-1069, 2018 | 52 | 2018 |
| Inhibition of FoxM1-mediated DNA repair by imipramine blue suppresses breast cancer growth and metastasis S Rajamanickam, S Panneerdoss, A Gorthi, S Timilsina, B Onyeagucha, ... Clinical Cancer Research 22 (14), 3524-3536, 2016 | 51 | 2016 |
| Musashi1 impacts radio-resistance in glioblastoma by controlling DNA-protein kinase catalytic subunit PR de Araujo, A Gorthi, AE da Silva, SS Tonapi, DT Vo, SC Burns, M Qiao, ... The American journal of pathology 186 (9), 2271-2278, 2016 | 47 | 2016 |
| Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA H Pan, M Jin, A Ghadiyaram, P Kaur, HE Miller, HM Ta, M Liu, Y Fan, ... Nucleic acids research 48 (10), 5639-5655, 2020 | 46 | 2020 |
| Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells A Zanotto-Filho, S Rajamanickam, E Loranc, VP Masamsetti, A Gorthi, ... Cancer letters 425, 101-115, 2018 | 34 | 2018 |
| Reconstruction of Ewing sarcoma developmental context from mass-scale transcriptomics reveals characteristics of EWSR1-FLI1 permissibility HE Miller, A Gorthi, N Bassani, LA Lawrence, BS Iskra, AJR Bishop Cancers 12 (4), 948, 2020 | 31 | 2020 |
| ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair AD Brown, BW Sager, A Gorthi, SS Tonapi, EJ Brown, AJR Bishop PloS one 9 (3), e91222, 2014 | 23 | 2014 |
| Automated risk assessment tool for pregnancy care A Gorthi, C Firtion, J Vepa 2009 Annual International Conference of the IEEE Engineering in Medicine and …, 2009 | 21 | 2009 |
| Ewing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage response A Gorthi, AJR Bishop Molecular & Cellular Oncology 5 (4), e1465014, 2018 | 17 | 2018 |
| Scaffold architecture and matrix strain modulate mesenchymal cell and microvascular growth and development in a time dependent manner G Chiou, E Jui, AC Rhea, A Gorthi, S Miar, FM Acosta, C Perez, Y Suhail, ... Cellular and molecular bioengineering 13, 507-526, 2020 | 9 | 2020 |
| The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells SW Criscione, MJ Martin, DB Oien, A Gorthi, RJ Miragaia, J Zhang, ... NPJ precision oncology 6 (1), 95, 2022 | 6 | 2022 |
| Methods for the analysis of breast cancer disorders N Dimitrova, S Khandige, S Kapaettu, A Gorthi, SP Kabekkodu, ... US Patent App. 13/641,282, 2013 | 2 | 2013 |
| Cohesin SA2 and EWSR1 in R-Loop Regulation H Wang, A Ghadiyaram, H Pan, Y Fan, P Kaur, A Gorthi, R Riehn, ... Biophysical Journal 116 (3), 505a, 2019 | 1 | 2019 |
| Computational tools for genome-wide R-loops identification and characterisation R Liu, A Gorthi, Y Jin, AJR Bishop, Y Chen International Journal of Computational Biology and Drug Design 10 (2), 123-136, 2017 | 1 | 2017 |
July Carolina RomeroUS Food and Drug AdministrationVerified email at fda.hhs.gov
