Synthesis and antitumor activity of 1, 5-disubstituted 1, 2, 4-triazoles as cis-restricted combretastatin analogues R Romagnoli, PG Baraldi, O Cruz-Lopez, C Lopez Cara, MD Carrion, ... Journal of medicinal chemistry 53 (10), 4248-4258, 2010 | 194 | 2010 |
Design, synthesis, and biological evaluation of thiophene analogues of chalcones R Romagnoli, PG Baraldi, MD Carrion, CL Cara, O Cruz-Lopez, D Preti, ... Bioorganic & medicinal chemistry 16 (10), 5367-5376, 2008 | 157 | 2008 |
Homochiral drugs: a demanding tendency of the pharmaceutical industry MC Nunez, ME Garcia-Rubino, A Conejo-Garcia, O Cruz-Lopez, ... Current medicinal chemistry 16 (16), 2064-2074, 2009 | 121 | 2009 |
Synthesis and biological evaluation of 1-methyl-2-(3′, 4′, 5′-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors R Romagnoli, PG Baraldi, T Sarkar, MD Carrion, CL Cara, O Cruz-Lopez, ... Journal of medicinal chemistry 51 (5), 1464-1468, 2008 | 119 | 2008 |
The P2X7 receptor as a therapeutic target R Romagnoli, PG Baraldi, O Cruz-Lopez, C Lopez-Cara, D Preti, ... Expert opinion on therapeutic targets 12 (5), 647-661, 2008 | 105 | 2008 |
Relationship between HMF intake and SMF formation in vivo: An animal and human study S Pastoriza de la Cueva, J Álvarez, Á Végvári, J Montilla‐Gómez, ... Molecular nutrition & food research 61 (3), 1600773, 2017 | 103 | 2017 |
Design, synthesis and structure–activity relationship of 2-(3′, 4′, 5′-trimethoxybenzoyl)-benzo [b] furan derivatives as a novel class of inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, MD Carrion, CL Cara, O Cruz-Lopez, ... Bioorganic & medicinal chemistry 17 (19), 6862-6871, 2009 | 90 | 2009 |
Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line R Sánchez-Martín, JM Campos, A Conejo-García, O Cruz-López, ... Journal of medicinal chemistry 48 (9), 3354-3363, 2005 | 77 | 2005 |
Hybrid α-bromoacryloylamido chalcones. Design, synthesis and biological evaluation R Romagnoli, PG Baraldi, MD Carrion, O Cruz-Lopez, CL Cara, ... Bioorganic & Medicinal Chemistry Letters 19 (7), 2022-2028, 2009 | 72 | 2009 |
Novel substituted quinazolines for potent EGFR tyrosine kinase inhibitors O Cruz-Lopez, A Conejo-Garcia, M C Nunez, M Kimatrai, ... Current medicinal chemistry 18 (7), 943-963, 2011 | 70 | 2011 |
2-Arylamino-4-amino-5-aroylthiazoles.“One-pot” synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, MD Carrion, O Cruz-Lopez, C Lopez Cara, ... Journal of medicinal chemistry 52 (17), 5551-5555, 2009 | 68 | 2009 |
Synthesis and biological evaluation of 2-(3′, 4′, 5′-trimethoxybenzoyl)-3-N, N-dimethylamino benzo [b] furan derivatives as inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, T Sarkar, MD Carrion, O Cruz-Lopez, CL Cara, ... Bioorganic & medicinal chemistry 16 (18), 8419-8426, 2008 | 65 | 2008 |
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N-(substituted) piperazin-1-yl] thiophenes as potent allosteric enhancers of the A1 adenosine receptor R Romagnoli, PG Baraldi, MD Carrion, CL Cara, O Cruz-Lopez, ... Journal of medicinal chemistry 51 (18), 5875-5879, 2008 | 56 | 2008 |
Substituted 2-(3′, 4′, 5′-trimethoxybenzoyl)-benzo [b] thiophene derivatives as potent tubulin polymerization inhibitors R Romagnoli, PG Baraldi, MD Carrion, O Cruz-Lopez, M Tolomeo, ... Bioorganic & medicinal chemistry 18 (14), 5114-5122, 2010 | 54 | 2010 |
New (RS)-benzoxazepin-purines with antitumour activity: the chiral switch from (RS)-2, 6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1, 2, 3, 5-tetrahydro-4, 1-benzoxazepin-3-yl]-9H … LC López-Cara, A Conejo-García, JA Marchal, G Macchione, ... European journal of medicinal chemistry 46 (1), 249-258, 2011 | 50 | 2011 |
Hybrid molecules containing benzo [4, 5] imidazo [1, 2-d][1, 2, 4] thiadiazole and α-bromoacryloyl moieties as potent apoptosis inducers on human myeloid leukaemia cells R Romagnoli, PG Baraldi, MD Carrion, O Cruz-Lopez, D Preti, MA Tabrizi, ... Bioorganic & medicinal chemistry letters 17 (10), 2844-2848, 2007 | 45 | 2007 |
Synthesis and Anticancer Activity of (R,S)‐9‐(2,3‐Dihydro‐1,4‐Benzoxathiin‐3‐ylmethyl)‐9H‐Purines M Díaz‐Gavilán, A Conejo‐García, O Cruz‐López, MC Nunez, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (1), 127-135, 2008 | 41 | 2008 |
Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero) arylethynyl thiophene derivatives R Romagnoli, PG Baraldi, O Cruz-Lopez, M Tolomeo, A Di Cristina, ... Bioorganic & medicinal chemistry letters 21 (9), 2746-2751, 2011 | 35 | 2011 |
Synthesis and biological evaluation of 2-amino-3-(3′, 4′, 5′-trimethoxybenzoyl)-6-substituted-4, 5, 6, 7-tetrahydrothieno [2, 3-c] pyridine derivatives as antimitotic agents … R Romagnoli, PG Baraldi, MD Carrion, O Cruz-Lopez, CL Cara, ... Bioorganic & medicinal chemistry letters 18 (18), 5041-5045, 2008 | 34 | 2008 |
HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib A Ramírez, H Boulaiz, C Morata-Tarifa, M Perán, G Jiménez, ... Oncotarget 5 (11), 3590, 2014 | 31 | 2014 |