Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal … PW Young, DR Buckle, BCC Cantello, H Chapman, JC Clapham, ... Journal of Pharmacology and Experimental Therapeutics 284 (2), 751-759, 1998 | 328 | 1998 |
Kinetic characterization of the recombinant ribonuclease from Bacillus amyloliquefaciens (barnase) and investigation of key residues in catalysis by site-directed mutagenesis DE Mossakowska, K Nyberg, AR Fersht Biochemistry 28 (9), 3843-3850, 1989 | 170 | 1989 |
NMR analysis of main-chain conformational preferences in an unfolded fibronectin-binding protein CJ Penkett, C Redfield, I Dodd, J Hubbard, DL McBay, DE Mossakowska, ... Journal of molecular biology 274 (2), 152-159, 1997 | 150 | 1997 |
Sequence of the OXA2 β-lactamase: comparison with other penicillin-reactive enzymes JW Dale, D Godwin, D Mossakowska, P Stephenson, S Wall FEBS letters 191 (1), 39-44, 1985 | 140 | 1985 |
Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1 MM Bellet, Y Nakahata, M Boudjelal, E Watts, DE Mossakowska, ... Proceedings of the National Academy of Sciences 110 (9), 3333-3338, 2013 | 119 | 2013 |
Oxacillin‐hydrolysing β‐lactamases: A comparative analysis at nucleotide and amino acid sequence levels D Mossakowska, NA Ali, JW Dale European journal of biochemistry 180 (2), 309-318, 1989 | 52 | 1989 |
Unlocking the secrets of the gatekeeper: methods for stabilizing and crystallizing GPCRs N Bertheleme, PS Chae, S Singh, D Mossakowska, MM Hann, KJ Smith, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (11), 2583-2591, 2013 | 45 | 2013 |
Effects of intracerebroventricular infusion of leptin in obese Zucker rats KA Al‐Barazanji, RE Buckingham, JRS Arch, A Haynes, ... Obesity research 5 (5), 387-394, 1997 | 42 | 1997 |
Overexpression inEscherichia coli, Folding, Purification, and Characterization of the First Three Short Consensus Repeat Modules of Human Complement Receptor Type 1 I Dodd, DE Mossakowska, P Camilleri, M Haran, P Hensley, EJ Lawlor, ... Protein Expression and Purification 6 (6), 727-736, 1995 | 42 | 1995 |
Structure‐activity relationships within the N‐terminal short consensus repeats (SCR) of human CR1 (C3b/C4b receptor, CD35): SCR 3 plays a critical role in inhibition of the … D Mossakowska, I Dodd, W Pindar, RAG Smith European journal of immunology 29 (6), 1955-1965, 1999 | 37 | 1999 |
Baculoviruses and mammalian cell‐based assays for drug screening JP Condreay, RS Ames, NJ Hassan, TA Kost, RV Merrihew, ... Advances in virus research 68, 255-286, 2006 | 35 | 2006 |
BacMam recombinant baculovirus in transporter expression: a study of BCRP and OATP1B1 NJ Hassan, DJ Pountney, C Ellis, DE Mossakowska Protein expression and purification 47 (2), 591-598, 2006 | 27 | 2006 |
In search of a small molecule agonist of the relaxin receptor RXFP1 for the treatment of liver fibrosis A McBride, AM Hoy, MJ Bamford, DE Mossakowska, MP Ruediger, ... Scientific Reports 7 (1), 10806, 2017 | 26 | 2017 |
Expression of nuclear hormone receptors in Escherichia coli DE Mossakowska Current opinion in biotechnology 9 (5), 502-505, 1998 | 19 | 1998 |
Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes S McKenna, E Malito, SL Rouse, F Abate, G Bensi, E Chiarot, F Micoli, ... Computational and Structural Biotechnology Journal 18, 650-660, 2020 | 18 | 2020 |
Conjugates of soluble peptidic compounds with membrane-binding agents RAG Smith, I Dodd, DEI Mossakowska US Patent 6,713,606, 2004 | 18 | 2004 |
CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model A Ketley, M Wojciechowska, S Ghidelli-Disse, P Bamborough, TK Ghosh, ... Science Translational Medicine 12 (541), eaaz2415, 2020 | 16 | 2020 |
Folding and conformational studies on SCR1-3 domains of human complement receptor 1 NS Clark, I Dodd, DE Mossakowska, RAG Smith, MG Gore Protein Engineering, Design and Selection 9 (10), 877-884, 1996 | 11 | 1996 |
Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase ATPase domain M Roué, A Agrawal, C Volker, D Mossakowska, C Mayer, BD Bax Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 10 | 2013 |
Conjugates of soluble peptidic compounds with membrane-binding agents RAG Smith, I Dodd, DEI Mossakowska | 8 | 1998 |