| Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice R Gordon, EA Albornoz, DC Christie, MR Langley, V Kumar, S Mantovani, ... Science translational medicine 10 (465), eaah4066, 2018 | 572 | 2018 |
| Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia N Panicker, S Sarkar, DS Harischandra, M Neal, TI Kam, H Jin, ... Journal of Experimental Medicine 216 (6), 1411-1430, 2019 | 198 | 2019 |
| Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark … M Ay, J Luo, M Langley, H Jin, V Anantharam, A Kanthasamy, ... Journal of neurochemistry 141 (5), 766-782, 2017 | 167 | 2017 |
| Epigallocatechin gallate has a neurorescue effect in a mouse model of Parkinson disease Q Xu, M Langley, AG Kanthasamy, MB Reddy The Journal of nutrition 147 (10), 1926-1931, 2017 | 124 | 2017 |
| Mito-apocynin prevents mitochondrial dysfunction, microglial activation, oxidative damage, and progressive neurodegeneration in MitoPark transgenic mice M Langley, A Ghosh, A Charli, S Sarkar, M Ay, J Luo, J Zielonka, T Brenza, ... Antioxidants & redox signaling 27 (14), 1048-1066, 2017 | 116 | 2017 |
| Mitoapocynin treatment protects against neuroinflammation and dopaminergic neurodegeneration in a preclinical animal model of Parkinson’s disease A Ghosh, MR Langley, DS Harischandra, ML Neal, H Jin, V Anantharam, ... Journal of Neuroimmune Pharmacology 11, 259-278, 2016 | 98 | 2016 |
| Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration R Gordon, ML Neal, J Luo, MR Langley, DS Harischandra, N Panicker, ... Nature communications 7 (1), 12932, 2016 | 90 | 2016 |
| Kv1. 3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease S Sarkar, HM Nguyen, E Malovic, J Luo, M Langley, BN Palanisamy, ... The Journal of Clinical Investigation 130 (8), 4195-4212, 2020 | 89 | 2020 |
| Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson’s disease: Relevance to gene and environment … MR Langley, S Ghaisas, M Ay, J Luo, BN Palanisamy, H Jin, ... Neurotoxicology 64, 240-255, 2018 | 55 | 2018 |
| High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system MR Langley, H Yoon, HN Kim, CI Choi, W Simon, L Kleppe, IR Lanza, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (3), 165630, 2020 | 43 | 2020 |
| MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson’s disease S Ghaisas, MR Langley, BN Palanisamy, S Dutta, K Narayanaswamy, ... Neurotoxicology 75, 186-199, 2019 | 38 | 2019 |
| Characterizing a mouse model for evaluation of countermeasures against hydrogen sulfide–induced neurotoxicity and neurological sequelae P Anantharam, EM Whitley, B Mahama, DS Kim, PM Imerman, D Shao, ... Annals of the New York Academy of Sciences 1400 (1), 46-64, 2017 | 34 | 2017 |
| Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes NM Frederick, PV Shah, A Didonna, MR Langley, AG Kanthasamy, P Opal Human molecular genetics 28 (8), 1343-1356, 2019 | 31 | 2019 |
| Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice. Sci Transl Med R Gordon, EA Albornoz, DC Christie, MR Langley, V Kumar, S Mantovani, ... | 31 | 2018 |
| Dietary influence on central nervous system myelin production, injury, and regeneration MR Langley, EM Triplet, IA Scarisbrick Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (7), 165779, 2020 | 23 | 2020 |
| Characterization of nonmotor behavioral impairments and their neurochemical mechanisms in the MitoPark mouse model of progressive neurodegeneration in Parkinson's disease MR Langley, S Ghaisas, BN Palanisamy, M Ay, H Jin, V Anantharam, ... Experimental neurology 341, 113716, 2021 | 20 | 2021 |
| Blocking the thrombin receptor promotes repair of demyelinated lesions in the adult brain H Yoon, CI Choi, EM Triplet, MR Langley, LS Kleppe, HN Kim, WL Simon, ... Journal of Neuroscience 40 (7), 1483-1500, 2020 | 19 | 2020 |
| A Western diet impairs CNS energy homeostasis and recovery after spinal cord injury: link to astrocyte metabolism HN Kim, MR Langley, WL Simon, H Yoon, L Kleppe, IR Lanza, ... Neurobiology of disease 141, 104934, 2020 | 17 | 2020 |
| Critical role of astrocyte NAD+ glycohydrolase in myelin injury and regeneration MR Langley, CI Choi, TR Peclat, Y Guo, WL Simon, H Yoon, L Kleppe, ... Journal of Neuroscience 41 (41), 8644-8667, 2021 | 14 | 2021 |
| The thrombin receptor restricts subventricular zone neural stem cell expansion and differentiation CI Choi, H Yoon, KL Drucker, MR Langley, L Kleppe, IA Scarisbrick Scientific reports 8 (1), 9360, 2018 | 14 | 2018 |
