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Ashutosh Kumar
Ashutosh Kumar
Professor, Department of Biosciences and Bioengineering, IIT Bombay, India
Verified email at iitb.ac.in - Homepage
Title
Cited by
Cited by
Year
Pre‐fibrillar α‐synuclein variants with impaired β‐structure increase neurotoxicity in Parkinson's disease models
DP Karpinar, MBG Balija, S Kügler, F Opazo, N Rezaei‐Ghaleh, ...
The EMBO journal 28 (20), 3256-3268, 2009
5672009
α-Synuclein aggregation nucleates through liquid–liquid phase separation
S Ray, N Singh, R Kumar, K Patel, S Pandey, D Datta, J Mahato, ...
Nature chemistry 12 (8), 705-716, 2020
4662020
Curcumin modulates α-synuclein aggregation and toxicity
PK Singh, V Kotia, D Ghosh, GM Mohite, A Kumar, SK Maji
ACS chemical neuroscience 4 (3), 393-407, 2013
2872013
Structural properties of pore-forming oligomers of α-synuclein
HY Kim, MK Cho, A Kumar, E Maier, C Siebenhaar, S Becker, ...
Journal of the American Chemical Society 131 (47), 17482-17489, 2009
2502009
The Parkinson’s disease-associated H50Q mutation accelerates α-synuclein aggregation in vitro
D Ghosh, M Mondal, GM Mohite, PK Singh, P Ranjan, A Anoop, S Ghosh, ...
Biochemistry 52 (40), 6925-6927, 2013
2192013
Structure based aggregation studies reveal the presence of helix-rich intermediate during α-Synuclein aggregation
D Ghosh, PK Singh, S Sahay, NN Jha, RS Jacob, S Sen, A Kumar, R Riek, ...
Scientific reports 5 (1), 9228, 2015
2152015
The Newly Discovered Parkinson’s Disease Associated Finnish Mutation (A53E) Attenuates α-Synuclein Aggregation and Membrane Binding
D Ghosh, S Sahay, P Ranjan, S Salot, GM Mohite, PK Singh, S Dwivedi, ...
Biochemistry 53 (41), 6419-6421, 2014
1882014
Self healing hydrogels composed of amyloid nano fibrils for cell culture and stem cell differentiation
RS Jacob, D Ghosh, PK Singh, SK Basu, NN Jha, S Das, PK Sukul, S Patil, ...
Biomaterials 54, 97-105, 2015
1812015
Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant α-synuclein
H Heise, MS Celej, S Becker, D Riedel, A Pelah, A Kumar, TM Jovin, ...
Journal of molecular biology 380 (3), 444-450, 2008
1192008
Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14 RELEVANCE TO ITS STORAGE AND SECRETION
A Anoop, S Ranganathan, BD Dhaked, NN Jha, S Pratihar, S Ghosh, ...
Journal of Biological Chemistry 289 (24), 16884-16903, 2014
802014
Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14 RELEVANCE TO ITS STORAGE AND SECRETION
A Anoop, S Ranganathan, BD Dhaked, NN Jha, S Pratihar, S Ghosh, ...
Journal of Biological Chemistry 289 (24), 16884-16903, 2014
802014
Structural comparison of mouse and human α-synuclein amyloid fibrils by solid-state NMR
G Lv, A Kumar, K Giller, ML Orcellet, D Riedel, CO Fernández, S Becker, ...
Journal of molecular biology 420 (1-2), 99-111, 2012
792012
Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules
RS Jacob, S Das, S Ghosh, A Anoop, NN Jha, T Khan, P Singru, A Kumar, ...
Scientific reports 6 (1), 23370, 2016
712016
Perturbation in Long-Range Contacts Modulates the Kinetics of Amyloid Formation in α-Synuclein Familial Mutants
P Ranjan, A Kumar
ACS chemical neuroscience 8 (10), 2235-2246, 2017
612017
Comparison of α-synuclein fibril inhibition by four different amyloid inhibitors
NN Jha, R Kumar, R Panigrahi, A Navalkar, D Ghosh, S Sahay, M Mondal, ...
ACS chemical neuroscience 8 (12), 2722-2733, 2017
592017
Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils
S Mehra, D Ghosh, R Kumar, M Mondal, LG Gadhe, S Das, A Anoop, ...
Journal of Biological Chemistry 293 (34), 12975-12991, 2018
542018
Dynamin interacts with members of the sumoylation machinery
RK Mishra, SS Jatiani, A Kumar, VR Simhadri, RV Hosur, R Mittal
Journal of Biological Chemistry 279 (30), 31445-31454, 2004
542004
Comparison of Kinetics, Toxicity, Oligomer Formation, and Membrane Binding Capacity of α-Synuclein Familial Mutations at the A53 Site, Including the Newly Discovered A53V Mutation
GM Mohite, R Kumar, R Panigrahi, A Navalkar, N Singh, D Datta, S Mehra, ...
Biochemistry 57 (35), 5183-5187, 2018
482018
Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy
A Kumar, H Heise, MJJ Blommers, P Krastel, E Schmitt, F Petersen, ...
Angew Chem Int Ed Engl 49 (41), 7504-7507, 2010
442010
NMR of unfolded proteins
A Chatterjee, A Kumar, J Chugh, S Srivastava, NS Bhavesh, RV Hosur
Journal of Chemical Sciences 117, 3-21, 2005
392005
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