Dll1-and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells L Pellegrinet, V Rodilla, Z Liu, S Chen, U Koch, L Espinosa, KH Kaestner, ... Gastroenterology 140 (4), 1230-1240. e7, 2011 | 493 | 2011 |
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer V Rodilla, A Villanueva, A Obrador-Hevia, À Robert-Moreno, ... Proceedings of the National Academy of Sciences 106 (15), 6315-6320, 2009 | 439 | 2009 |
Phosphorylation by glycogen synthase kinase-3β down-regulates Notch activity, a link for Notch and Wnt pathways L Espinosa, J Inglés-Esteve, C Aguilera, A Bigas Journal of Biological Chemistry 278 (34), 32227-32235, 2003 | 414 | 2003 |
RBPJκ-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus O Ehm, C Göritz, M Covic, I Schäffner, TJ Schwarz, E Karaca, B Kempkes, ... Journal of Neuroscience 30 (41), 13794-13807, 2010 | 367 | 2010 |
RBPjκ-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells À Robert-Moreno, L Espinosa, JL de la Pompa, A Bigas Oxford University Press for The Company of Biologists Limited 132 (5), 1117-1126, 2005 | 347 | 2005 |
The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia L Espinosa, S Cathelin, T D'Altri, T Trimarchi, A Statnikov, J Guiu, ... Cancer cell 18 (3), 268-281, 2010 | 334 | 2010 |
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1 À Robert‐Moreno, J Guiu, C Ruiz‐Herguido, ME López, J Inglés‐Esteve, ... The EMBO journal 27 (13), 1886-1895, 2008 | 229 | 2008 |
Hematopoietic stem cells: to be or Notch to be A Bigas, L Espinosa Blood, The Journal of the American Society of Hematology 119 (14), 3226-3235, 2012 | 218 | 2012 |
Notch signal strength controls cell fate in the haemogenic endothelium L Gama-Norton, E Ferrando, C Ruiz-Herguido, Z Liu, J Guiu, AB Islam, ... Nature communications 6 (1), 8510, 2015 | 167 | 2015 |
Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer V Fernandez-Majada, C Aguilera, A Villanueva, F Vilardell, ... Proceedings of the National Academy of Sciences 104 (1), 276-281, 2007 | 167 | 2007 |
Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer V Fernandez-Majada, C Aguilera, A Villanueva, F Vilardell, ... Proceedings of the National Academy of Sciences 104 (1), 276-281, 2007 | 167 | 2007 |
Recruitment of IκBα to the hes1 promoter is associated with transcriptional repression C Aguilera, R Hoya-Arias, G Haegeman, L Espinosa, A Bigas Proceedings of the National Academy of Sciences 101 (47), 16537-16542, 2004 | 166 | 2004 |
CD146 and its soluble form regulate monocyte transendothelial migration N Bardin, M Blot-Chabaud, N Despoix, A Kebir, K Harhouri, JP Arsanto, ... Arteriosclerosis, thrombosis, and vascular biology 29 (5), 746-753, 2009 | 162 | 2009 |
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling J Guiu, R Shimizu, T D’Altri, ST Fraser, J Hatakeyama, EH Bresnick, ... Journal of Experimental Medicine 210 (1), 71-84, 2013 | 143 | 2013 |
Hematopoietic stem cell development requires transient Wnt/β-catenin activity C Ruiz-Herguido, J Guiu, T D'Altri, J Inglés-Esteve, E Dzierzak, ... Journal of Experimental Medicine 209 (8), 1457-1468, 2012 | 143 | 2012 |
Genome‐wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: the GR@ ACE project S Moreno‐Grau, I De Rojas, I Hernández, I Quintela, L Montrreal, ... Alzheimer's & Dementia 15 (10), 1333-1347, 2019 | 133 | 2019 |
IκBα and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFκB pathways L Espinosa, J Inglés-Esteve, A Robert-Moreno, A Bigas Molecular biology of the cell 14 (2), 491-502, 2003 | 133 | 2003 |
Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch E López-Arribillaga, V Rodilla, L Pellegrinet, J Guiu, M Iglesias, ... Development 142 (1), 41-50, 2015 | 110 | 2015 |
The Notch pathway in the developing hematopoietic system A Bigas, À Robert-Moreno, L Espinosa International Journal of Developmental Biology 54 (6-7), 1175-1188, 2010 | 102 | 2010 |
p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes R Pippa, L Espinosa, G Gundem, R Garcia-Escudero, A Dominguez, ... Oncogene 31 (38), 4207-4220, 2012 | 90 | 2012 |