| The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013 | 1145 | 2013 |
| Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7 IE Wertz, S Kusam, C Lam, T Okamoto, W Sandoval, DJ Anderson, ... Nature 471 (7336), 110-114, 2011 | 864 | 2011 |
| A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii M Yamamoto, M Okuyama, JS Ma, T Kimura, N Kamiyama, H Saiga, ... Immunity 37 (2), 302-313, 2012 | 356 | 2012 |
| Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling M Yamamoto, T Okamoto, K Takeda, S Sato, H Sanjo, S Uematsu, ... Nature immunology 7 (9), 962-970, 2006 | 327 | 2006 |
| Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90 T Okamoto, Y Nishimura, T Ichimura, K Suzuki, T Miyamura, T Suzuki, ... The EMBO journal 25 (20), 5015-5025, 2006 | 290 | 2006 |
| Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B I Hamamoto, Y Nishimura, T Okamoto, H Aizaki, M Liu, Y Mori, T Abe, ... Journal of virology 79 (21), 13473-13482, 2005 | 262 | 2005 |
| An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies Y Liu, WT Soh, J Kishikawa, M Hirose, EE Nakayama, S Li, M Sasai, ... Cell 184 (13), 3452-3466. e18, 2021 | 224 | 2021 |
| Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53 GL Kelly, S Grabow, SP Glaser, L Fitzsimmons, BJ Aubrey, T Okamoto, ... Genes & development 28 (1), 58-70, 2014 | 183 | 2014 |
| Stabilizing the pro-apoptotic BimBH3 helix (BimSAHB) does not necessarily enhance affinity or biological activity T Okamoto, K Zobel, A Fedorova, C Quan, H Yang, WJ Fairbrother, ... ACS chemical biology 8 (2), 297-302, 2013 | 159 | 2013 |
| ATF6β is a host cellular target of the Toxoplasma gondii virulence factor ROP18 M Yamamoto, JS Ma, C Mueller, N Kamiyama, H Saiga, E Kubo, T Kimura, ... Journal of Experimental Medicine 208 (7), 1533-1546, 2011 | 159 | 2011 |
| Ifit1 inhibits Japanese encephalitis virus replication through binding to 5′ capped 2′-O unmethylated RNA T Kimura, H Katoh, H Kayama, H Saiga, M Okuyama, T Okamoto, ... Journal of virology 87 (18), 9997-10003, 2013 | 125 | 2013 |
| Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral propagation K Okamoto, Y Mori, Y Komoda, T Okamoto, M Okochi, M Takeda, T Suzuki, ... Journal of virology 82 (17), 8349-8361, 2008 | 122 | 2008 |
| Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation H Katoh, T Okamoto, T Fukuhara, H Kambara, E Morita, Y Mori, ... Journal of virology 87 (1), 489-502, 2013 | 109 | 2013 |
| Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2 Y Higuchi, T Suzuki, T Arimori, N Ikemura, E Mihara, Y Kirita, E Ohgitani, ... Nature communications 12 (1), 3802, 2021 | 107 | 2021 |
| Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA K Masuda, B Ripley, KK Nyati, PK Dubey, MMU Zaman, H Hanieh, M Higa, ... Journal of Experimental Medicine 213 (4), 605-619, 2016 | 94 | 2016 |
| Nucleolar protein B23 interacts with Japanese encephalitis virus core protein and participates in viral replication Y Tsuda, Y Mori, T Abe, T Yamashita, T Okamoto, T Ichimura, K Moriishi, ... Microbiology and immunology 50 (3), 225-234, 2006 | 93 | 2006 |
| Regulation of apoptosis during flavivirus infection T Okamoto, T Suzuki, S Kusakabe, M Tokunaga, J Hirano, Y Miyata, ... Viruses 9 (9), 243, 2017 | 92 | 2017 |
| Lipoprotein receptors redundantly participate in entry of hepatitis C virus S Yamamoto, T Fukuhara, C Ono, K Uemura, Y Kawachi, M Shiokawa, ... PLoS pathogens 12 (5), e1005610, 2016 | 89 | 2016 |
| Enhanced TLR-mediated NF-IL6–dependent gene expression by Trib1 deficiency M Yamamoto, S Uematsu, T Okamoto, Y Matsuura, S Sato, H Kumar, ... The Journal of experimental medicine 204 (9), 2233-2239, 2007 | 88 | 2007 |
| Amphipathic α-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles T Fukuhara, M Wada, S Nakamura, C Ono, M Shiokawa, S Yamamoto, ... PLoS pathogens 10 (12), e1004534, 2014 | 83 | 2014 |
