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Kyle M. Stiers
Kyle M. Stiers
Bayer
Verified email at mail.missouri.edu
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Cited by
Year
The metabolic map into the pathomechanism and treatment of PGM1-CDG
S Radenkovic, MJ Bird, TL Emmerzaal, SY Wong, C Felgueira, KM Stiers, ...
The American Journal of Human Genetics 104 (5), 835-846, 2019
732019
Compromised catalysis and potential folding defects in in vitro studies of missense mutants associated with hereditary phosphoglucomutase 1 deficiency
Y Lee, KM Stiers, BN Kain, LJ Beamer
Journal of Biological Chemistry 289 (46), 32010-32019, 2014
482014
Biology, mechanism, and structure of enzymes in the α-D-phosphohexomutase superfamily
KM Stiers, AG Muenks, LJ Beamer
Advances in protein chemistry and structural biology 109, 265-304, 2017
422017
Structure, biochemistry, and gene expression patterns of the proline biosynthetic enzyme pyrroline-5-carboxylate reductase (PYCR), an emerging cancer therapy target
AN Bogner, KM Stiers, JJ Tanner
Amino Acids 53 (12), 1817-1834, 2021
312021
Structure and characterization of a class 3B proline utilization A: ligand-induced dimerization and importance of the C-terminal domain for catalysis
DA Korasick, TT Gamage, S Christgen, KM Stiers, LJ Beamer, MT Henzl, ...
Journal of Biological Chemistry 292 (23), 9652-9665, 2017
222017
Induced structural disorder as a molecular mechanism for enzyme dysfunction in phosphoglucomutase 1 deficiency
KM Stiers, BN Kain, AC Graham, LJ Beamer
Journal of molecular biology 428 (8), 1493-1505, 2016
222016
Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1
AG Muenks, KM Stiers, LJ Beamer
PLoS One 12 (8), e0183563, 2017
192017
A hotspot for disease-associated variants of human PGM1 is associated with impaired ligand binding and loop dynamics
KM Stiers, LJ Beamer
Structure 26 (10), 1337-1345. e3, 2018
172018
Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono-, Di-, and Trifluorinated d-Gluco-heptuloses by Glucokinase: Tunable …
JS Zhu, KM Stiers, SM Winter, AD Garcia, AF Versini, LJ Beamer, ...
ACS omega 4 (4), 7029-7037, 2019
142019
Asp263 missense variants perturb the active site of human phosphoglucomutase 1
KM Stiers, AC Graham, BN Kain, LJ Beamer
The FEBS journal 284 (6), 937-947, 2017
142017
Inhibitory Evaluation of αPMM/PGM from Pseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study
JS Zhu, KM Stiers, E Soleimani, BR Groves, LJ Beamer, DL Jakeman
The Journal of Organic Chemistry 84 (15), 9627-9636, 2019
132019
Trapping conformational states of a flavin-dependent N-monooxygenase in crystallo reveals protein and flavin dynamics
AC Campbell, KM Stiers, JSM Del Campo, R Mehra-Chaudhary, ...
Journal of Biological Chemistry 295 (38), 13239-13249, 2020
122020
Fourth report on chicken genes and chromosomes 2022
J Smith, JM Alfieri, N Anthony, P Arensburger, GN Athrey, J Balacco, ...
Cytogenetic and Genome Research 162 (8-9), 405-528, 2023
92023
Structural and dynamical description of the enzymatic reaction of a phosphohexomutase
KM Stiers, AC Graham, JS Zhu, DL Jakeman, JC Nix, LJ Beamer
Structural Dynamics 6 (2), 2019
92019
Cautionary Tale of Using Tris(alkyl)phosphine Reducing Agents with NAD+-Dependent Enzymes
SM Patel, TG Smith, M Morton, KM Stiers, J Seravalli, SJ Mayclin, ...
Biochemistry 59 (36), 3285-3289, 2020
82020
Assessment and impacts of phosphorylation on protein flexibility of the α-D-phosphohexomutases
KM Stiers, LJ Beamer
Methods in Enzymology 607, 241-267, 2018
62018
Phosphorylation-Dependent Effects on the Structural Flexibility of Phosphoglucosamine Mutase from Bacillus anthracis
KM Stiers, J Xu, Y Lee, ZR Addison, SR Van Doren, LJ Beamer
ACS omega 2 (11), 8445-8452, 2017
42017
Synchrotron-based macromolecular crystallography module for an undergraduate biochemistry laboratory course
KM Stiers, CB Lee, JC Nix, JJ Tanner, LJ Beamer
Journal of Applied Crystallography 49 (6), 2235-2243, 2016
42016
Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans‐4‐hydroxy‐L‐proline
AN Bogner, KM Stiers, CM McKay, DF Becker, JJ Tanner
Protein Science 30 (8), 1714-1722, 2021
32021
A missense variant remote from the active site impairs stability of human phosphoglucomutase 1
KM Stiers, RP Hansen, BA Daghlas, KN Mason, JS Zhu, DL Jakeman, ...
Journal of Inherited Metabolic Disease 43 (4), 861-870, 2020
22020
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