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Ivan Budyak
Ivan Budyak
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Year
Glutamic acid-rich proteins of rod photoreceptors are natively unfolded
R Batra-Safferling, K Abarca-Heidemann, HG Korschen, C Tziatzios, ...
Journal of biological chemistry 281 (3), 1449-1460, 2006
712006
Functional characterization of sensory rhodopsin II from Halobacterium salinarum expressed in Escherichia coli
OS Mironova, RG Efremov, B Person, J Heberle, IL Budyak, G Büldt, ...
FEBS letters 579 (14), 3147-3151, 2005
452005
The role of aromatic–aromatic interactions in strand–strand stabilization of β-sheets
IL Budyak, A Zhuravleva, LM Gierasch
Journal of molecular biology 425 (18), 3522-3535, 2013
342013
Systematic prediction of human membrane receptor interactions
Y Qi, HK Dhiman, N Bhola, I Budyak, S Kar, D Man, A Dutta, K Tirupula, ...
Proteomics 9 (23), 5243-5255, 2009
332009
Delicate balance between functionally required flexibility and aggregation risk in a β-rich protein
MC Ferrolino, A Zhuravleva, IL Budyak, B Krishnan, LM Gierasch
Biochemistry 52 (49), 8843-8854, 2013
292013
Early folding events protect aggregation-prone regions of a β-rich protein
IL Budyak, B Krishnan, AM Marcelino-Cruz, MC Ferrolino, A Zhuravleva, ...
Structure 21 (3), 476-485, 2013
202013
Shape and oligomerization state of the cytoplasmic domain of the phototaxis transducer II from Natronobacterium pharaonis
IL Budyak, V Pipich, OS Mironova, R Schlesinger, G Zaccai, ...
Proceedings of the National Academy of Sciences 103 (42), 15428-15433, 2006
182006
Technical decision-making with higher order structure data: Specific binding of a nonionic detergent perturbs higher order structure of a therapeutic monoclonal antibody
IL Budyak, BL Doyle, WF Weiss IV
Journal of Pharmaceutical Sciences 104 (4), 1543-1547, 2015
142015
Best practices for aggregate quantitation of antibody therapeutics by sedimentation velocity analytical ultracentrifugation
GM Bou-Assaf, IL Budyak, M Brenowitz, ES Day, D Hayes, J Hill, ...
Journal of pharmaceutical sciences 111 (7), 2121-2133, 2022
92022
An optical alignment system improves precision of soluble aggregate quantitation by sedimentation velocity analytical ultracentrifugation
BL Doyle, IL Budyak, AP Rauk, WF Weiss IV
Analytical biochemistry 531, 16-19, 2017
92017
FT-IR difference spectroscopy elucidates crucial interactions of sensory rhodopsin I with the cognate transducer HtrI
OS Mironova, IL Budyak, G Büldt, R Schlesinger, J Heberle
Biochemistry 46 (33), 9399-9405, 2007
62007
Revisit PEG-Induced precipitation assay for protein solubility assessment of monoclonal antibody formulations
MJ Scannell, MW Hyatt, IL Budyak, MA Woldeyes, Y Wang
Pharmaceutical Research 38, 1947-1960, 2021
52021
Signal relay from sensory rhodopsin I to the cognate transducer HtrI: Assessing the critical change in hydrogen-bonding between Tyr-210 and Asn-53
I Radu, IL Budyak, T Hoomann, YJ Kim, M Engelhard, J Labahn, G Büldt, ...
Biophysical chemistry 150 (1-3), 23-28, 2010
52010
Predicting Experimental B22 Values and the Effects of Histidine Charge States for Monoclonal Antibodies Using Coarse-Grained Molecular Simulations
H Shahfar, CJ O’Brien, IL Budyak, CJ Roberts
Molecular Pharmaceutics 19 (11), 3820-3830, 2022
42022
Quantitation of soluble aggregates by sedimentation velocity analytical ultracentrifugation using an optical alignment system–Aspects of method validation
BL Doyle, AP Rauk, WF Weiss IV, IL Budyak
Analytical biochemistry 605, 113837, 2020
42020
Flexibility of the Cytoplasmic Domain of the Phototaxis Transducer II from Natronomonas pharaonis
IL Budyak, OS Mironova, N Yanamala, V Manoharan, G Büldt, ...
Journal of Biophysics 2008, 2008
22008
Rapid Quantitation of Various Therapeutic Monoclonal Antibodies Using Membranes with Fc-Specific Ligands
J Yang, R Ostafe, CJ Welch, B Verhalen, IL Budyak, ML Bruening
Analytical Chemistry 95 (22), 8541-8551, 2023
12023
Estimating analytical variability in two-dimensional data
IL Budyak, KL Griffiths, WF Weiss IV
Analytical biochemistry 513, 36-38, 2016
12016
Early long-range contacts in the folding of intracellular lipid-binding proteins favor native beta-barrel closure and disfavor aggregation
I Budyak, B Krishnan, AM Marcelino-Cruz, L Gierasch
PROTEIN SCIENCE 21, 188-188, 2012
12012
Evaluating Clinical Safety and Analytical Impact of Subvisible Silicone Oil Particles in Biopharmaceutical Products
M Saggu, GM Bou-Assaf, R Bucher, IL Budyak, J Buecheler, S Cao, ...
Journal of Pharmaceutical Sciences, 2024
2024
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