A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene EP Reddy, RK Reynolds, E Santos, M Barbacid Nature 300 (5888), 149-152, 1982 | 1810 | 1982 |
Ras in cancer and developmental diseases A Fernández-Medarde, E Santos Genes & cancer 2 (3), 344-358, 2011 | 1140 | 2011 |
T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB-and Harvey-MSV transforming genes E Santos, SR Tronick, SA Aaronson, S Pulciani, M Barbacid Nature 298 (5872), 343-347, 1982 | 816 | 1982 |
Oncogenes in solid human tumours S Pulciani, E Santos, AV Lauver, LK Long, SA Aaronson, M Barbacid Nature 300 (5892), 539-542, 1982 | 602 | 1982 |
Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient E Santos, D Martin-Zanca, EP Reddy, MA Pierotti, G Della Porta, ... Science 223 (4637), 661-664, 1984 | 539 | 1984 |
Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study H Gacaferi, GS Collaborative, COVIDSurg Collaborative Anaesthesia 76 (6), 2021 | 532* | 2021 |
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development LM Esteban, C Vicario-Abejón, P Fernández-Salguero, ... Molecular and cellular biology, 2001 | 411 | 2001 |
Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells. S Pulciani, E Santos, AV Lauver, LK Long, KC Robbins, M Barbacid Proceedings of the National Academy of Sciences 79 (9), 2845-2849, 1982 | 391 | 1982 |
Functional specificity of ras isoforms: so similar but so different E Castellano, E Santos Genes & cancer 2 (3), 216-231, 2011 | 351 | 2011 |
Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival M Drosten, A Dhawahir, EYM Sum, J Urosevic, CG Lechuga, LM Esteban, ... The EMBO journal 29 (6), 1091-1104, 2010 | 340 | 2010 |
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption G Schumann, LJ Coin, A Lourdusamy, P Charoen, KH Berger, D Stacey, ... Proceedings of the National Academy of Sciences 108 (17), 7119-7124, 2011 | 316 | 2011 |
Structural and functional properties of ras proteins E Santos, AR Nebreda The FASEB journal 3 (10), 2151-2163, 1989 | 303 | 1989 |
A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25 PG Hysi, TL Young, DA Mackey, T Andrew, A Fernández-Medarde, ... Nature genetics 42 (10), 902-905, 2010 | 275 | 2010 |
Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study J Glasbey, A Ademuyiwa, A Adisa, E AlAmeer, AP Arnaud, F Ayasra, ... The Lancet Oncology 22 (11), 1507-1517, 2021 | 232 | 2021 |
Differentiation of 3T3-L1 Fibroblasts to Adipocytes Induced by Transfection of ras Oncogenes M Benito, A Porras, AR Nebreda, E Santos Science 253 (5019), 565-568, 1991 | 222 | 1991 |
Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation J Font de Mora, A Porras, N Ahn, E Santos Molecular and cellular biology 17 (10), 6068-6075, 1997 | 218 | 1997 |
ras gene Amplification and malignant transformation S Pulciani, E Santos, LK Long, V Sorrentino, M Barbacid Molecular and cellular biology, 1985 | 212 | 1985 |
Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALKXL chimeric gene with transforming activity L Hernandez, S Beà, B Bellosillo, M Pinyol, B Falini, A Carbone, G Ott, ... The American journal of pathology 160 (4), 1487-1494, 2002 | 155 | 2002 |
Spontaneous activation of a human proto-oncogene. E Santos, EP Reddy, S Pulciani, RJ Feldmann, M Barbacid Proceedings of the National Academy of Sciences 80 (15), 4679-4683, 1983 | 150 | 1983 |
Endogenous expression of HrasG12V induces developmental defects and neoplasms with copy number imbalances of the oncogene X Chen, N Mitsutake, K LaPerle, N Akeno, P Zanzonico, VA Longo, ... Proceedings of the National Academy of Sciences 106 (19), 7979-7984, 2009 | 149 | 2009 |