The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity J Liu, M Gao, J He, K Wu, S Lin, L Jin, Y Chen, H Liu, J Shi, X Wang, ... Nature 591 (7849), 322-326, 2021 | 201 | 2021 |
Polycomb group proteins regulate chromatin architecture in mouse oocytes and early embryos Z Du, H Zheng, YK Kawamura, K Zhang, J Gassler, S Powell, Q Xu, Z Lin, ... Molecular cell 77 (4), 825-839. e7, 2020 | 120 | 2020 |
Genomic repeats categorize genes with distinct functions for orchestrated regulation JY Lu, W Shao, L Chang, Y Yin, T Li, H Zhang, Y Hong, M Percharde, ... Cell reports 30 (10), 3296-3311. e5, 2020 | 113 | 2020 |
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome JY Lu, L Chang, T Li, T Wang, Y Yin, G Zhan, X Han, K Zhang, Y Tao, ... Cell research 31 (6), 613-630, 2021 | 112 | 2021 |
Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells L Chang, M Li, S Shao, C Li, S Ai, B Xue, Y Hou, Y Zhang, R Li, X Fan, ... Protein & Cell 13 (4), 258-280, 2022 | 48 | 2022 |
Study of RNA polymerase II clustering inside live-cell nuclei using Bayesian nanoscopy X Chen, M Wei, MM Zheng, J Zhao, H Hao, L Chang, P Xi, Y Sun ACS nano 10 (2), 2447-2454, 2016 | 45 | 2016 |
Multiplexed sgRNA expression allows versatile single nonrepetitive DNA labeling and endogenous gene regulation S Shao, L Chang, Y Sun, Y Hou, X Fan, Y Sun ACS Synthetic Biology 7 (1), 176-186, 2018 | 39 | 2018 |
GMars-Q enables long-term live-cell parallelized reversible saturable optical fluorescence transitions nanoscopy S Wang, X Chen, L Chang, R Xue, H Duan, Y Sun ACS nano 10 (10), 9136-9144, 2016 | 33 | 2016 |
Development of bimolecular fluorescence complementation using rsEGFP2 for detection and super-resolution imaging of protein-protein interactions in live cells S Wang, M Ding, X Chen, L Chang, Y Sun Biomedical Optics Express 8 (6), 3119-3131, 2017 | 28 | 2017 |
GMars-T enabling multimodal subdiffraction structural and functional fluorescence imaging in live cells S Wang, X Chen, L Chang, M Ding, R Xue, H Duan, Y Sun Analytical chemistry 90 (11), 6626-6634, 2018 | 19 | 2018 |
Droplet-based single-cell joint profiling of histone modifications and transcriptomes Y Xie, C Zhu, Z Wang, M Tastemel, L Chang, YE Li, B Ren Nature Structural & Molecular Biology 30 (10), 1428-1433, 2023 | 10 | 2023 |
L1 and B1 repeats blueprint the spatial organization of chromatin JY Lu, L Chang, T Li, T Wang, Y Yin, G Zhan, K Zhang, M Percharde, ... biorxiv, 802173, 2019 | 7 | 2019 |
AgoFISH: cost-effective in situ labelling of genomic loci based on DNA-guided dTtAgo protein L Chang, G Sheng, Y Zhang, S Shao, Y Wang, Y Sun Nanoscale Horizons 4 (4), 918-923, 2019 | 7 | 2019 |
Conserved and divergent gene regulatory programs of the mammalian neocortex NR Zemke, EJ Armand, W Wang, S Lee, J Zhou, YE Li, H Liu, W Tian, ... Nature 624 (7991), 390-402, 2023 | 6 | 2023 |
Single‐cell third‐generation sequencing‐based multi‐omics uncovers gene expression changes governed by ecDNA and structural variants in cancer cells L Chang, E Deng, J Wang, W Zhou, J Ao, R Liu, D Su, X Fan Clinical and Translational Medicine 13 (8), e1351, 2023 | 6 | 2023 |
Illuminating the structure and dynamics of chromatin by fluorescence labeling S Shao, L Chang, Y Hou, Y Sun Frontiers in biology 12, 241-257, 2017 | 4 | 2017 |
PN-ImTLSM facilitates high-throughput low background single-molecule localization microscopy deep in the cell B Xue, C Zhou, Y Qin, Y Li, Y Sun, L Chang, S Shao, Y Li, M Zhang, ... Biophysics Reports 7 (4), 313, 2021 | 2 | 2021 |
Chromatin-lamin B1 interaction promotes genomic compartmentalization and constrains chromatin dynamics L Chang, M Li, S Shao, B Xue, Y Hou, Y Zhang, R Li, C Li, Y Sun BioRxiv, 601849, 2019 | 2 | 2019 |
Single-cell analysis of isoform switching and transposable element expression during preimplantation embryonic development C Wang, Z Shi, Q Huang, R Liu, D Su, L Chang, C Xiao, X Fan PLoS biology 22 (2), e3002505, 2024 | 1 | 2024 |
Droplet Hi-C for Fast and Scalable Profiling of Chromatin Architecture in Single Cells L Chang, Y Xie, B Taylor, Z Wang, J Sun, TR Tan, R Bejar, CC Chen, ... bioRxiv, 2024.04. 18.590148, 2024 | | 2024 |