| Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Cancer discovery 5 (12), 1282-1295, 2015 | 1198 | 2015 |
| A new view of transcriptome complexity and regulation through the lens of local splicing variations J Vaquero-Garcia, A Barrera, MR Gazzara, J Gonzalez-Vallinas, ... elife 5, e11752, 2016 | 413 | 2016 |
| Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding IC McDowell, A Barrera, AM D'Ippolito, CM Vockley, LK Hong, ... Genome research 28 (9), 1272-1284, 2018 | 110 | 2018 |
| Pre-established chromatin interactions mediate the genomic response to glucocorticoids AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, ... Cell systems 7 (2), 146-160. e7, 2018 | 97 | 2018 |
| Targeted transcriptional modulation with type I CRISPR–Cas systems in human cells A Pickar-Oliver, JB Black, MM Lewis, KJ Mutchnick, TS Klann, KA Gilcrest, ... Nature biotechnology 37 (12), 1493-1501, 2019 | 85 | 2019 |
| Transgenic mice for in vivo epigenome editing with CRISPR-based systems MP Gemberling, K Siklenka, E Rodriguez, KR Tonn-Eisinger, A Barrera, ... Nature methods 18 (8), 965-974, 2021 | 69 | 2021 |
| PRiMeUM: a model for predicting risk of metastasis in uveal melanoma J Vaquero-Garcia, E Lalonde, KG Ewens, J Ebrahimzadeh, ... Investigative ophthalmology & visual science 58 (10), 4096-4105, 2017 | 62 | 2017 |
| c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program ME Parker, A Barrera, JD Wheaton, MK Zuberbuehler, DSJ Allan, ... Journal of Experimental Medicine 217 (1), 2020 | 57 | 2020 |
| Master regulators and cofactors of human neuronal cell fate specification identified by CRISPR gene activation screens JB Black, SR McCutcheon, S Dube, A Barrera, TS Klann, GA Rice, ... Cell reports 33 (9), 2020 | 44 | 2020 |
| Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer S Prekovic, K Schuurman, I Mayayo-Peralta, AG Manjón, M Buijs, S Yavuz, ... Nature Communications 12 (1), 4360, 2021 | 38 | 2021 |
| Human genome-wide measurement of drug-responsive regulatory activity GD Johnson, A Barrera, IC McDowell, AM D’Ippolito, WH Majoros, ... Nature communications 9 (1), 5317, 2018 | 38 | 2018 |
| Decoding the role of regulatory element polymorphisms in complex disease CM Vockley, A Barrera, TE Reddy Current opinion in genetics & development 43, 38-45, 2017 | 32 | 2017 |
| Analysis of the protein domain and domain architecture content in fungi and its application in the search of new antifungal targets A Barrera, A Alastruey-Izquierdo, MJ Martín, I Cuesta, JA Vizcaíno PLoS computational biology 10 (7), e1003733, 2014 | 29 | 2014 |
| Causal network inference from gene transcriptional time-series response to glucocorticoids J Lu, B Dumitrascu, IC McDowell, B Jo, A Barrera, LK Hong, SM Leichter, ... PLoS computational biology 17 (1), e1008223, 2021 | 28 | 2021 |
| AP-1 subunits converge promiscuously at enhancers to potentiate transcription J Seo, DD Koçak, LC Bartelt, CA Williams, A Barrera, CA Gersbach, ... Genome research 31 (4), 538-550, 2021 | 19 | 2021 |
| Correcting signal biases and detecting regulatory elements in STARR-seq data YS Kim, GD Johnson, J Seo, A Barrera, TN Cowart, WH Majoros, A Ochoa, ... Genome Research 31 (5), 877-889, 2021 | 15 | 2021 |
| ZBTB7A promotes virus-host homeostasis during human coronavirus 229E infection X Zhu, JD Trimarco, CA Williams, A Barrera, TE Reddy, NS Heaton Cell reports 41 (4), 2022 | 12 | 2022 |
| Genome-wide annotation of gene regulatory elements linked to cell fitness TS Klann, A Barrera, AR Ettyreddy, RA Rickels, J Bryois, S Jiang, ... BioRxiv, 2021.03. 08.434470, 2021 | 7 | 2021 |
| Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens SR McCutcheon, AM Swartz, MC Brown, A Barrera, C McRoberts Amador, ... Nature Genetics 55 (12), 2211-2223, 2023 | 6 | 2023 |
| Multicenter integrated analysis of noncoding CRISPRi screens D Yao, J Tycko, JW Oh, LR Bounds, SJ Gosai, L Lataniotis, ... Nature Methods, 1-12, 2024 | 5 | 2024 |
Timothy E ReddyAssociate Professor, Duke UniversityVerified email at duke.edu
