JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia A Bonetto, T Aydogdu, X Jin, Z Zhang, R Zhan, L Puzis, LG Koniaris, ... American Journal of Physiology-Endocrinology and Metabolism 303 (3), E410-E421, 2012 | 439 | 2012 |
STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia A Bonetto, T Aydogdu, N Kunzevitzky, DC Guttridge, S Khuri, LG Koniaris, ... PloS one 6 (7), e22538, 2011 | 382 | 2011 |
STAT3 in the systemic inflammation of cancer cachexia TA Zimmers, ML Fishel, A Bonetto Seminars in cell & developmental biology 54, 28-41, 2016 | 234 | 2016 |
IGF-1 is downregulated in experimental cancer cachexia P Costelli, M Muscaritoli, M Bossola, F Penna, P Reffo, A Bonetto, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2006 | 226 | 2006 |
Muscle myostatin signalling is enhanced in experimental cancer cachexia P Costelli, M Muscaritoli, A Bonetto, F Penna, P Reffo, M Bossola, ... European journal of clinical investigation 38 (7), 531-538, 2008 | 222 | 2008 |
Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs R Barreto, DL Waning, H Gao, Y Liu, TA Zimmers, A Bonetto Oncotarget 7 (28), 43442, 2016 | 191 | 2016 |
Cachexia induced by cancer and chemotherapy yield distinct perturbations to energy metabolism F Pin, R Barreto, ME Couch, A Bonetto, TM O'Connell Journal of cachexia, sarcopenia and muscle 10 (1), 140-154, 2019 | 183 | 2019 |
Cancer and chemotherapy contribute to muscle loss by activating common signaling pathways R Barreto, G Mandili, FA Witzmann, F Novelli, TA Zimmers, A Bonetto Frontiers in physiology 7, 472, 2016 | 171 | 2016 |
Preservation of muscle mass as a strategy to reduce the toxic effects of cancer chemotherapy on body composition F Pin, ME Couch, A Bonetto Current opinion in supportive and palliative care 12 (4), 420-426, 2018 | 160 | 2018 |
Assessment of muscle mass and strength in mice A Bonetto, DC Andersson, DL Waning BoneKEy reports 4, 2015 | 129 | 2015 |
Muscle atrophy in experimental cancer cachexia: is the IGF‐1 signaling pathway involved? F Penna, A Bonetto, M Muscaritoli, D Costamagna, VG Minero, G Bonelli, ... International journal of cancer 127 (7), 1706-1717, 2010 | 129 | 2010 |
Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia JE Rupert, A Narasimhan, DHA Jengelley, Y Jiang, J Liu, E Au, ... Journal of Experimental Medicine 218 (6), e20190450, 2021 | 110 | 2021 |
The colon-26 carcinoma tumor-bearing mouse as a model for the study of cancer cachexia A Bonetto, JE Rupert, R Barreto, TA Zimmers JoVE (Journal of Visualized Experiments), e54893, 2016 | 109 | 2016 |
β-hydroxy-β-methylbutyrate (HMB) attenuates muscle and body weight loss in experimental cancer cachexia Z Aversa, A Bonetto, P Costelli, VG Minero, F Penna, FM Baccino, S Lucia, ... International journal of oncology 38 (3), 713-720, 2011 | 106 | 2011 |
Therapeutic potential of proteasome inhibition in Duchenne and Becker muscular dystrophies E Gazzerro, S Assereto, A Bonetto, F Sotgia, S Scarfì, A Pistorio, ... The American journal of pathology 176 (4), 1863-1877, 2010 | 97 | 2010 |
Changes in myostatin signaling in non-weight-losing cancer patients Z Aversa, A Bonetto, F Penna, P Costelli, G Di Rienzo, A Lacitignola, ... Annals of surgical oncology 19, 1350-1356, 2012 | 91 | 2012 |
Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice A Bonetto, F Penna, VG Minero, P Reffo, G Bonelli, FM Baccino, P Costelli Current cancer drug targets 9 (5), 608-616, 2009 | 85 | 2009 |
Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia F Pin, R Barreto, Y Kitase, S Mitra, CE Erne, LJ Novinger, TA Zimmers, ... Journal of cachexia, sarcopenia and muscle 9 (4), 685-700, 2018 | 82 | 2018 |
Are antioxidants useful for treating skeletal muscle atrophy? A Bonetto, F Penna, M Muscaritoli, VG Minero, FR Fanelli, FM Baccino, ... Free Radical Biology and Medicine 47 (7), 906-916, 2009 | 80 | 2009 |
Effect of the specific proteasome inhibitor bortezomib on cancer‐related muscle wasting F Penna, A Bonetto, Z Aversa, VG Minero, F Rossi Fanelli, P Costelli, ... Journal of cachexia, sarcopenia and muscle 7 (3), 345-354, 2016 | 76 | 2016 |