| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13172* | 2021 |
| Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. YH Hsiang, R Hertzberg, S Hecht, LF Liu Journal of Biological Chemistry 260 (27), 14873-14878, 1985 | 3197 | 1985 |
| DNA topoisomerase poisons as antitumor drugs LF Liu Annual review of biochemistry 58 (1), 351-375, 1989 | 2550 | 1989 |
| Supercoiling of the DNA template during transcription. LF Liu, JC Wang Proceedings of the National Academy of Sciences 84 (20), 7024-7027, 1987 | 2379 | 1987 |
| Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II KM Tewey, TC Rowe, L Yang, BD Halligan, LF Liu Science 226 (4673), 466-468, 1984 | 1944 | 1984 |
| Identification of the molecular basis of doxorubicin-induced cardiotoxicity S Zhang, X Liu, T Bawa-Khalfe, LS Lu, YL Lyu, LF Liu, ETH Yeh Nature medicine 18 (11), 1639-1642, 2012 | 1925 | 2012 |
| Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin YH Hsiang, MG Lihou, LF Liu Cancer research 49 (18), 5077-5082, 1989 | 1351 | 1989 |
| Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin YH Hsiang, LF Liu Cancer research 48 (7), 1722-1726, 1988 | 1195 | 1988 |
| DNA topoisomerases: essential enzymes and lethal targets AY Chen, LF Liu Annual review of pharmacology and toxicology 34 (1), 191-218, 1994 | 1083 | 1994 |
| Topoisomerase II is a structural component of mitotic chromosome scaffolds. WC Earnshaw, B Halligan, CA Cooke, MM Heck, LF Liu The Journal of cell biology 100 (5), 1706-1715, 1985 | 924 | 1985 |
| Transcription generates positively and negatively supercoiled domains in the template HY Wu, S Shyy, JC Wang, LF Liu Cell 53 (3), 433-440, 1988 | 879 | 1988 |
| Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. GL Chen, L Yang, TC Rowe, BD Halligan, KM Tewey, LF Liu Journal of Biological Chemistry 259 (21), 13560-13566, 1984 | 870 | 1984 |
| DNA topoisomerase I—targeted chemotherapy of human colon cancer in xenografts BC Giovanella, JS Stehlin, ME Wall, MC Wani, AW Nicholas, LF Liu, ... Science 246 (4933), 1046-1048, 1989 | 867 | 1989 |
| Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide. EM Nelson, KM Tewey, LF Liu Proceedings of the National Academy of Sciences 81 (5), 1361-1365, 1984 | 762 | 1984 |
| Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. KM Tewey, GL Chen, EM Nelson, LF Liu Journal of Biological Chemistry 259 (14), 9182-9187, 1984 | 739 | 1984 |
| Topoisomerase IIβ–mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane YL Lyu, JE Kerrigan, CP Lin, AM Azarova, YC Tsai, Y Ban, LF Liu Cancer research 67 (18), 8839-8846, 2007 | 736 | 2007 |
| Cleavage of DNA by mammalian DNA topoisomerase II. LF Liu, TC Rowe, L Yang, KM Tewey, GL Chen Journal of Biological Chemistry 258 (24), 15365-15370, 1983 | 708 | 1983 |
| Mechanism of action of camptothecin LF Liu, SD Desai, TKUN LI, Y Mao, MEI Sun, SAIP SIM Annals of the New York Academy of Sciences 922 (1), 1-10, 2000 | 707 | 2000 |
| Topoisomerase-targeting antitumor drugs P D'arpa, LF Liu Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 989 (2), 163-177, 1989 | 699 | 1989 |
| Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break LF Liu, CC Liu, BM Alberts Cell 19 (3), 697-707, 1980 | 679 | 1980 |
