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Matthew S. Waitkus
Matthew S. Waitkus
Verified email at duke.edu - Homepage
Title
Cited by
Cited by
Year
Isocitrate dehydrogenase mutations in gliomas
MS Waitkus, BH Diplas, H Yan
Neuro-oncology 18 (1), 16-26, 2015
2972015
Biological role and therapeutic potential of IDH mutations in cancer
MS Waitkus, BH Diplas, H Yan
Cancer cell 34 (2), 186-195, 2018
2942018
The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma
BH Diplas, X He, JA Brosnan-Cashman, H Liu, LH Chen, Z Wang, ...
Nature communications 9 (1), 2087, 2018
1512018
The integrated genomic and epigenomic landscape of brainstem glioma
LH Chen, C Pan, BH Diplas, C Xu, LJ Hansen, Y Wu, X Chen, Y Geng, ...
Nature communications 11 (1), 3077, 2020
592020
Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation
R Yang, LH Chen, LJ Hansen, AB Carpenter, CJ Moure, H Liu, CJ Pirozzi, ...
Cancer research 77 (22), 6097-6108, 2017
512017
Signal integration and gene induction by a functionally distinct STAT3 phosphoform
MS Waitkus, UM Chandrasekharan, B Willard, TL Tee, JK Hsieh, ...
Molecular and cellular biology 34 (10), 1800-1811, 2014
452014
Mutant IDH1 disrupts the mouse subventricular zone and alters brain tumor progression
CJ Pirozzi, AB Carpenter, MS Waitkus, CY Wang, H Zhu, LJ Hansen, ...
Molecular Cancer Research 15 (5), 507-520, 2017
432017
Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities
MS Waitkus, CJ Pirozzi, CJ Moure, BH Diplas, LJ Hansen, AB Carpenter, ...
Cancer research 78 (1), 36-50, 2018
392018
Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas
BH Diplas, H Liu, R Yang, LJ Hansen, AL Zachem, F Zhao, DD Bigner, ...
Neuro-oncology 21 (4), 440-450, 2019
342019
Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition
JT Low, V Chandramohan, ML Bowie, MC Brown, MS Waitkus, A Briley, ...
Cancer Cell 40 (5), 439-440, 2022
292022
Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe
Y Liu, AB Carpenter, CJ Pirozzi, H Yuan, MS Waitkus, Z Zhou, L Hansen, ...
Nanotechnology 30 (27), 275101, 2019
252019
Targeting mutant PPM1D sensitizes diffuse intrinsic pontine glioma cells to the PARP inhibitor olaparib
Z Wang, C Xu, BH Diplas, CJ Moure, CPJ Chen, LH Chen, C Du, H Zhu, ...
Molecular Cancer Research 18 (7), 968-980, 2020
242020
CRISPR editing of mutant IDH1 R132H induces a CpG methylation-low state in patient-derived glioma models of G-CIMP
CJ Moure, BH Diplas, LH Chen, R Yang, CJ Pirozzi, Z Wang, I Spasojevic, ...
Molecular Cancer Research 17 (10), 2042-2050, 2019
202019
Synergistic induction of mitogen-activated protein kinase phosphatase-1 by thrombin and epidermal growth factor requires vascular endothelial growth factor receptor-2
UM Chandrasekharan, M Waitkus, CM Kinney, A Walters-Stewart, ...
Arteriosclerosis, thrombosis, and vascular biology 30 (10), 1983-1989, 2010
192010
STAT3-mediated coincidence detection regulates noncanonical immediate early gene induction
MS Waitkus, UM Chandrasekharan, B Willard, SJ Haque, PE DiCorleto
Journal of Biological Chemistry 288 (17), 11988-12003, 2013
182013
Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression
JD Boerckel, UM Chandrasekharan, MS Waitkus, EG Tillmaand, R Bartlett, ...
Arteriosclerosis, thrombosis, and vascular biology 34 (5), 1020-1031, 2014
172014
Targeting isocitrate dehydrogenase mutations in cancer: emerging evidence and diverging strategies
MS Waitkus, H Yan
Clinical Cancer Research 27 (2), 383-388, 2021
152021
Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression
UM Chandrasekharan, L Dechert, UI Davidson, M Waitkus, L Mavrakis, ...
Science signaling 6 (284), ra60-ra60, 2013
142013
Antitumor activity of a mitochondrial-targeted HSP90 inhibitor in gliomas
S Wei, D Yin, S Yu, X Lin, MR Savani, K Du, Y Ku, D Wu, S Li, H Liu, ...
Clinical Cancer Research 28 (10), 2180-2195, 2022
122022
A modified nucleoside 6-Thio-2′-deoxyguanosine exhibits antitumor activity in gliomas
S Yu, S Wei, M Savani, X Lin, K Du, I Mender, S Siteni, T Vasilopoulos, ...
Clinical Cancer Research 27 (24), 6800-6814, 2021
102021
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