| Indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors in clinical trials for cancer immunotherapy K Tang, YH Wu, Y Song, B Yu Journal of Hematology & Oncology 14, 1-21, 2021 | 190 | 2021 |
| Double-edged roles of protein tyrosine phosphatase SHP2 in cancer and its inhibitors in clinical trials Y Song, M Zhao, H Zhang, B Yu Pharmacology & therapeutics 230, 107966, 2022 | 65 | 2022 |
| Strategies targeting protein tyrosine phosphatase SHP2 for cancer therapy Y Song, S Wang, M Zhao, X Yang, B Yu Journal of Medicinal Chemistry 65 (4), 3066-3079, 2022 | 47 | 2022 |
| Annual review of lysine-specific demethylase 1 (LSD1/KDM1A) inhibitors in 2021 Y Song, H Zhang, X Yang, Y Shi, B Yu European Journal of Medicinal Chemistry 228, 114042, 2022 | 29 | 2022 |
| A multifunctional cross-validation high-throughput screening protocol enabling the discovery of new SHP2 inhibitors Y Song, M Zhao, Y Wu, B Yu, HM Liu Acta Pharmaceutica Sinica B 11 (3), 750-762, 2021 | 26 | 2021 |
| Repurposing antidepressants for anticancer drug discovery Y Song, X Yang, B Yu Drug discovery today 27 (7), 1924-1935, 2022 | 23 | 2022 |
| Brønsted acid-promoted ‘on–water’C (sp3)-H functionalization for the synthesis of isoindolinone/[1, 2, 4] triazolo [1, 5-a] pyrimidine derivatives targeting the SKP2-CKS1 … S Yuan, S Wang, M Zhao, D Zhang, J Chen, JX Li, J Zhang, Y Song, ... Chinese Chemical Letters 31 (2), 349-352, 2020 | 21 | 2020 |
| Structural insights into the CRTC2–CREB complex assembly on CRE Y Song, L Zhai, JV Swain, Y Chen, P Wang, L Chen, Y Liu, S Xiang Journal of molecular biology 430 (13), 1926-1939, 2018 | 21 | 2018 |
| Crystallographic landscape of SHP2 provides molecular insights for SHP2 targeted drug discovery Y Song, X Yang, S Wang, M Zhao, B Yu Medicinal Research Reviews 42 (5), 1781-1821, 2022 | 17 | 2022 |
| Harnessing the cyclization strategy for new drug discovery K Tang, S Wang, W Gao, Y Song, B Yu Acta Pharmaceutica Sinica B 12 (12), 4309-4326, 2022 | 15 | 2022 |
| Recent advances of LSD1/KDM1A inhibitors for disease therapy C Zhang, Z Wang, Y Shi, B Yu, Y Song Bioorganic Chemistry 134, 106443, 2023 | 7 | 2023 |
| Structural and functional landscape of FAD-dependent histone lysine demethylases for new drug discovery Y Song, S Wang, B Yu Journal of Medicinal Chemistry 66 (1), 71-94, 2022 | 7 | 2022 |
| Structure-based design, synthesis and biological evaluation of aminopyrazines as highly potent, selective, and cellularly active allosteric SHP2 inhibitors K Tang, M Zhao, YH Wu, Q Wu, S Wang, Y Dong, B Yu, Y Song, HM Liu European Journal of Medicinal Chemistry 230, 114106, 2022 | 6 | 2022 |
| Combining EGFR inhibitors with SHP2 or LSD1 inhibitors to overcome multidrug resistance in cancer H Zhang, X Yang, Y Song, B Yu Future Medicinal Chemistry 14 (8), 527-529, 2022 | 4 | 2022 |
| KRAS Q61H mutation confers cancer cells with acquired resistance to SHP2 inhibition YH Song, XY Yang, B Yu Pharmaceutical Fronts 4 (01), e40-e42, 2022 | 3 | 2022 |
| Targeting SHP2 for Cancer Treatment: Advances and Prospects Y Song, B Yu Handbook of Cancer and Immunology, 1-19, 2023 | 2 | 2023 |
| Emerging therapeutic approaches of SHP2-targeted modulators X Yang, J Xiong, B Yu, Y Song Future Medicinal Chemistry 16 (4), 291-294, 2024 | 1 | 2024 |
| Discovery and pharmacodynamic evaluation of the novel butene lactone derivative M355 against influenza A virus in vitro and in vivo J Geng, X Hu, Z Zhang, Z Gu, Y Li, X Mou, L Mao, Y Ge, X Yang, Y Song, ... Journal of Medical Virology 94 (9), 4393-4405, 2022 | 1 | 2022 |
| Discovery of TK-642 as a highly potent, selective, orally bioavailable pyrazolopyrazine-based allosteric SHP2 inhibitor K Tang, S Wang, S Feng, X Yang, Y Guo, X Ren, L Bai, B Yu, HM Liu, ... Acta Pharmaceutica Sinica B, 2024 | | 2024 |
| Development of a robust HTRF assay with USP7 full length protein expressed in E. coli prokaryotic system for the identification of USP7 inhibitors Y Song, S Wang, M Zhao, B Yu Journal of Pharmaceutical and Biomedical Analysis 227, 115305, 2023 | | 2023 |
BIN YU, PhDProfessor of Medicinal Chemistry, College of Chemistry, Zhengzhou UniversityVerified email at zzu.edu.cn
