| Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides. T Shirasaka, MF Kavlick, T Ueno, WY Gao, E Kojima, ML Alcaide, ... Proceedings of the National Academy of Sciences 92 (6), 2398-2402, 1995 | 487 | 1995 |
| Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: an in vitro comparative study. T Shirasaka, R Yarchoan, MC O'Brien, RN Husson, BD Anderson, ... Proceedings of the National Academy of Sciences 90 (2), 562-566, 1993 | 167 | 1993 |
| Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (−)-2′, 3′-dideoxy-3′-thiacytidine MF Kavlick, T Shirasaka, E Kojima, JM Pluda, F Hui Jr, R Yarchoan, ... Antiviral Research 28 (2), 133-146, 1995 | 104 | 1995 |
| Vertical transmission of human immunodeficiency virus type 1: autologous neutralizing antibody, virus load, and virus phenotype RN Husson, Y Lan, E Kojima, D Venzon, H Mitsuya, K McIntosh The Journal of pediatrics 126 (6), 865-871, 1995 | 71 | 1995 |
| Lipophilic halogenated congeners of 2', 3'-dideoxypurine nucleosides active against human immunodeficiency virus in vitro. T Shirasaka, K Murakami, H Ford Jr, JA Kelley, H Yoshioka, E Kojima, ... Proceedings of the National Academy of Sciences 87 (23), 9426-9430, 1990 | 68 | 1990 |
| Escherichia coli mediated biosynthesis and in vitro anti-HIV activity of lipophilic 6-halo-2', 3'-dideoxypurine nucleosides K Murakami, T Shirasaka, H Yoshioka, E Kojima, S Aoki, H Ford Jr, ... Journal of medicinal chemistry 34 (5), 1606-1612, 1991 | 53 | 1991 |
| Diastereo-and enantioselective reduction of α, β-diketodithiane with the baker's yeast T Fujisawa, E Kojima, T Itoh, T Sato Tetrahedron letters 26 (49), 6089-6092, 1985 | 53 | 1985 |
| NP-06: a novel anti-human immunodeficiency virus polypeptide produced by a Streptomyces species S Chokekijchai, E Kojima, S Anderson, M Nomizu, M Tanaka, M Machida, ... Antimicrobial agents and chemotherapy 39 (10), 2345-2347, 1995 | 44 | 1995 |
| 2', 3'-dideoxy purine nucleoside E Kojima, H Yoshioka, H Fukinbara, K Murakami US Patent 5,053,499, 1991 | 43 | 1991 |
| Human Immunodeficiency Virus Type 1 (HIV-l) Viremia Changes and Development of Drug-Related Mutations in Patients with Symptomatic HIV-l Infection Receiving Alternating or … E Kojima, T Shirasaka, BD Anderson, S Chokekijchai, SM Steinberg, ... Journal of Infectious Diseases 171 (5), 1152-1158, 1995 | 39 | 1995 |
| A C2 Symmetry-Based HIV Protease Inhibitor, A77003, Irreversibly Inhibits Infectivity of HIV-1 In Vitro S KAGEYAMA, DT HOEKZEMA, Y MURAKAWA, E KOJIMA, ... AIDS research and human retroviruses 10 (6), 735-743, 1994 | 33 | 1994 |
| 2', 3'-dideoxy purine nucleosides and process for the preparation thereof E Kojima, H Yoshioka, H Fukinbara, K Murakami US Patent 5,563,049, 1996 | 25 | 1996 |
| Monitoring the activity of antiviral therapy for HIV infection using a polymerase chain reaction method coupled with reverse transcription E Kojima, T Shirasaka, B Anderson, S Chokekijchai, S Sei, R Yarchoan, ... AIDS 7, S101-106, 1993 | 24 | 1993 |
| (2S,3S)-1-Phenylthio-2,3-butanediol. A Useful Chiral Building Block for a Simple Syntheses of (4R,5S)-5-Hydroxyhexan-4-olide and (4R,5S)-5-Hydroxy-2 … T Fujisawa, E Kojima, T Sato Chemistry Letters 16 (11), 2227-2228, 1987 | 19 | 1987 |
| Emergence of HIV-1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides T Shirasaka, M Kavlick, T Ueno, WY Gao, E Kojima, ML Alcaide, ... Proc Natl Acad Sci USA 92 (2398), 402, 1995 | 12 | 1995 |
| Identification of drug-related genotypic changes in HIV-1 from serum using the selective polymerase chain reaction BD Anderson, T Shirasaka, E Kojima, R Yarchoan, H Mitsuya Antiviral research 25 (3-4), 245-258, 1994 | 9 | 1994 |
| Lipophilic 6-halo-2′, 3′-dideoxypurine nucleosides: potential antiretroviral agents targeting HIV-associated neurologic disorders T Shirasaka, K Watanabe, H Yoshioka, E Kojima, S Aoki, K Murakami, ... Advances in molecular biology and targeted treatment for AIDS, 323-333, 1991 | 9 | 1991 |
| ENANTIOSELECTIVE SYNTHESIS OF α-HYDROXYTHIOACETALS BY THE BAKER’S YEAST REDUCTION OF α-KETOTHIOACETALS T Fujisawa, E Kojima, T Itoh, T Sato Chemistry letters 14 (11), 1751-1754, 1985 | 8 | 1985 |
| Antiviral effects of 6-chloro-2', 3'-dideoxyguanosine in rhesus monkeys acutely infected with simian immunodeficiency virus. Y Fujii, R Mukai, H Akari, M Machida, K Mori, M Takasaka, E Kojima, ... Antiviral chemistry & chemotherapy 9 (1), 85-92, 1998 | 7 | 1998 |
| Efficacy of 6-chloro-2', 3'-dideoxyguanosine (6-Cl-ddG) on rhesus macaque monkeys chronically infected with simian immunodeficiency virus (SIVmac239) Y Fujii, R Mukai, K Mori, H Akari, I Otani, F Ono, E Kojima, M Takasaka, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 16 (5), 313-317, 1997 | 7 | 1997 |
