| A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform. CA Sartorius, MY Melville, AR Hovland, L Tung, GS Takimoto, KB Horwitz Molecular endocrinology 8 (10), 1347-1360, 1994 | 431 | 1994 |
| New T47D breast cancer cell lines for the independent study of progesterone B-and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists … CA Sartorius, SD Groshong, LA Miller, RL Powell, L Tung, GS Takimoto, ... Cancer research 54 (14), 3868-3877, 1994 | 284 | 1994 |
| Patient-derived xenograft (PDX) models in basic and translational breast cancer research LE Dobrolecki, SD Airhart, DG Alferez, S Aparicio, F Behbod, ... Cancer and Metastasis Reviews 35, 547-573, 2016 | 252 | 2016 |
| Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP CA Sartorius, L Tung, GS Takimoto, KB Horwitz Journal of Biological Chemistry 268 (13), 9262-9266, 1993 | 213 | 1993 |
| Fibroblast subtypes regulate responsiveness of luminal breast cancer to estrogen HM Brechbuhl, J Finlay-Schultz, TM Yamamoto, AE Gillen, DM Cittelly, ... Clinical Cancer Research 23 (7), 1710-1721, 2017 | 206 | 2017 |
| Different pathways regulate expression of the skeletal myosin heavy chain genes DL Allen, CA Sartorius, LK Sycuro, LA Leinwand Journal of Biological Chemistry 276 (47), 43524-43533, 2001 | 205 | 2001 |
| Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes JC Harrell, WW Dye, DC Allred, P Jedlicka, NS Spoelstra, CA Sartorius, ... Cancer research 66 (18), 9308-9315, 2006 | 176 | 2006 |
| Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts KB Horwitz, WW Dye, JC Harrell, P Kabos, CA Sartorius Proceedings of the National Academy of Sciences 105 (15), 5774-5779, 2008 | 163 | 2008 |
| Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures P Kabos, J Finlay-Schultz, C Li, E Kline, C Finlayson, J Wisell, CA Manuel, ... Breast cancer research and treatment 135, 415-432, 2012 | 155 | 2012 |
| The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer TE Hickey, LA Selth, KM Chia, G Laven-Law, HH Milioli, D Roden, ... Nature medicine 27 (2), 310-320, 2021 | 153 | 2021 |
| Cooperative dynamics of AR and ER activity in breast cancer NC D'Amato, MA Gordon, B Babbs, NS Spoelstra, KT Carson Butterfield, ... Molecular cancer research 14 (11), 1054-1067, 2016 | 140 | 2016 |
| Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4 DM Cittelly, J Finlay-Schultz, EN Howe, NS Spoelstra, SD Axlund, ... Oncogene 32 (20), 2555-2564, 2013 | 138 | 2013 |
| Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch JM Haughian, MP Pinto, JC Harrell, BS Bliesner, KM Joensuu, WW Dye, ... Proceedings of the National Academy of Sciences 109 (8), 2742-2747, 2012 | 125 | 2012 |
| Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers P Kabos, JM Haughian, X Wang, WW Dye, C Finlayson, A Elias, ... Breast cancer research and treatment 128, 45-55, 2011 | 121 | 2011 |
| Myosin heavy chains IIa and IId are functionally distinct in the mouse CA Sartorius, BD Lu, L Acakpo-Satchivi, RP Jacobsen, WC Byrnes, ... The Journal of cell biology 141 (4), 943-953, 1998 | 120 | 1998 |
| Progesterone receptors (PR)-B and-A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B L Tung, H Abdel-Hafiz, T Shen, DME Harvell, LK Nitao, JK Richer, ... Molecular endocrinology 20 (11), 2656-2670, 2006 | 119 | 2006 |
| Progesterone receptors A and B differentially affect the growth of estrogen-dependent human breast tumor xenografts CA Sartorius, T Shen, KB Horwitz Breast cancer research and treatment 79, 287-299, 2003 | 115 | 2003 |
| Growth and muscle defects in mice lacking adult myosin heavy chain genes LJR Acakpo-Satchivi, W Edelmann, C Sartorius, BD Lu, PA Wahr, ... The Journal of cell biology 139 (5), 1219-1229, 1997 | 115 | 1997 |
| Progestins in hormone replacement therapies reactivate cancer stem cells in women with preexisting breast cancers: a hypothesis KB Horwitz, CA Sartorius The Journal of Clinical Endocrinology & Metabolism 93 (9), 3295-3298, 2008 | 111 | 2008 |
| Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and … R Iwanaga, CA Wang, DS Micalizzi, JC Harrell, P Jedlicka, CA Sartorius, ... Breast Cancer Research 14, 1-14, 2012 | 110 | 2012 |
