| 1, 2, 3-Triazole-[2, 5-Bis-O-(tert-butyldimethylsilyl)-. beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'', 2''-oxathiole 2'', 2''-dioxide)(TSAO) Analogs: Synthesis and Anti … R Alvarez, S Velazquez, A San-Felix, S Aquaro, ED Clercq, CF Perno, ... Journal of medicinal chemistry 37 (24), 4185-4194, 1994 | 1021 | 1994 |
| 2', 5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'', 2''-oxathiole-2'', 2'-dioxide) pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human … J Balzarini, MJ Perez-Perez, A San-Felix, D Schols, CF Perno, ... Proceedings of the National Academy of Sciences 89 (10), 4392-4396, 1992 | 252 | 1992 |
| 3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2', 5'-bis-O-(tert-butyldimethylsilyl)-. beta … MJ Camarasa, MJ Perez-Perez, A San-Felix, J Balzarini, E De Clercq Journal of Medicinal Chemistry 35 (15), 2721-2727, 1992 | 167 | 1992 |
| Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2', 5'-bis-O-(tert … J Balzarini, MJ Pérez-Pérez, A San-Felix, MJ Camarasa, IC Bathurst, ... Journal of Biological Chemistry 267 (17), 11831-11838, 1992 | 144 | 1992 |
| TSAO analogs. Stereospecific synthesis and anti-HIV-1 activity of 1-[2', 5'-bis-O-(tert-butyldimethylsilyl)-. beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'', 2''-oxathiole … MJ Perez-Perez, A San-Felix, J Balzarini, E De Clercq, MJ Camarasa Journal of medicinal chemistry 35 (16), 2988-2995, 1992 | 122 | 1992 |
| Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2', 5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'', 2 … J Balzarini, A Karlsson, AM Vandamme, MJ Pérez-Pérez, H Zhang, ... Proceedings of the National Academy of Sciences 90 (15), 6952-6956, 1993 | 110 | 1993 |
| Dimerization inhibitors of HIV-1 reverse transcriptase, protease and integrase: a single mode of inhibition for the three HIV enzymes? MJ Camarasa, S Velázquez, A San-Félix, MJ Pérez-Pérez, F Gago Antiviral research 71 (2-3), 260-267, 2006 | 88 | 2006 |
| Identification of a Putative Binding Site for [2‘,5‘-Bis-O-(tert-butyldimethylsilyl)-β-d-ribofuranosyl]-3‘-spiro-5‘ ‘-(4‘ ‘-amino-1‘ ‘,2‘ ‘-oxathiole-2‘ ‘,2‘ ‘-dioxide … F Rodríguez-Barrios, C Pérez, E Lobatón, S Velázquez, C Chamorro, ... Journal of Medicinal Chemistry 44 (12), 1853-1865, 2001 | 83 | 2001 |
| Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with … J Balzarini, MJ Perez-Perez, S Velazquez, A San-Felix, MJ Camarasa, ... Proceedings of the National Academy of Sciences 92 (12), 5470-5474, 1995 | 73 | 1995 |
| A new procedure for the synthesis of glycosyl isothiocyanates MJ Camarasa, P Fernández-Resa, MT García-López, G Federico, ... Synthesis 1984 (06), 509-510, 1984 | 72 | 1984 |
| 3′-spiro-5′′-(4′′-amino-1′′, 2′′-oxathiole-2′′, 2′′-dioxide)(TSAO) derivatives of purine and pyrimidine nucleosides as potent and selective inhibitors of human … J Balzarini, MJ Pérez-Pérez, A San-Félix, S Velazquez, MJ Camarasa, ... Antimicrob. Agents Chemother 36 (5), 1073-1080, 1992 | 69 | 1992 |
| TSAO compounds: the comprehensive story of a unique family of HIV-1 specific inhibitors of reverse transcriptase MJ Camarasa, A San-Félix, S Velázquez, MJ Pérez-Pérez, F Gago, ... Current topics in medicinal chemistry 4 (9), 945-963, 2004 | 67 | 2004 |
| Synthesis and anti-HIV activity of [AZT]-[TSAO-T] and [AZT]-[HEPT] dimers as potential multifunctional inhibitors of HIV-1 reverse transcriptase S Velazquez, R Alvarez, A San-Felix, ML Jimeno, E De Clercq, J Balzarini, ... Journal of medicinal chemistry 38 (10), 1641-1649, 1995 | 59 | 1995 |
| Novel series of TSAO-T derivatives. Synthesis and anti-HIV-1 activity of 4-, 5-, and 6-substituted pyrimidine analogs A San-Felix, S Velazquez, MJ Perez-Perez, J Balzarini, E De Clercq, ... Journal of medicinal chemistry 37 (4), 453-460, 1994 | 56 | 1994 |
| Cyanosugars—II: Synthesis of hexopyranosyl cyanides by reaction of glycals with trimethylsilyl cyanide G Federico, A San Felix, P Fernández-Resa Tetrahedron 39 (9), 1617-1620, 1983 | 55 | 1983 |
| Human immunodeficiency virus type 1-specific [2', 5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5"-(4"-amino-1", 2"-oxathiole-2", 2"-dioxide)-purine … J Balzarini, S Velazquez, A San-Felix, A Karlsson, MJ Perez-Perez, ... Molecular pharmacology 43 (1), 109-114, 1993 | 50 | 1993 |
| Linear and branched alkyl-esters and amides of gallic acid and other (mono-, di-and tri-) hydroxy benzoyl derivatives as promising anti-HCV inhibitors E Rivero-Buceta, P Carrero, EG Doyagueez, A Madrona, E Quesada, ... European journal of medicinal chemistry 92, 656-671, 2015 | 47 | 2015 |
| Targeting HIV entry through interaction with envelope glycoprotein 120 (gp120): synthesis and antiviral evaluation of 1, 3, 5-triazines with aromatic amino acids V Lozano, L Aguado, B Hoorelbeke, M Renders, MJ Camarasa, D Schols, ... Journal of medicinal chemistry 54 (15), 5335-5348, 2011 | 44 | 2011 |
| TSAO analogs. 3. Synthesis and anti-HIV-1 activity of 2', 5'-bis-O-(tert-butyldimethylsilyl)-. beta.-D-ribofuranosyl 3'-spiro-5"-(4"-amino-1", 2"-oxathiole 2", 2"-dioxide … S Velazquez, A San-Felix, MJ Perez-Perez, J Balzarini, E De Clercq, ... Journal of medicinal chemistry 36 (22), 3230-3239, 1993 | 43 | 1993 |
| Marked inhibitory activity of non-nucleoside reverse transcriptase inhibitors against human immunodeficiency virus type 1 when combined with (-) 2', 3'-dideoxy-3'-thiacytidine. J Balzarini, H Pelemans, MJ Pérez-Pérez, A San-Felix, MJ Camarasa, ... Molecular pharmacology 49 (5), 882-890, 1996 | 42 | 1996 |
