The roles of neuregulin-1 in cardiac development, homeostasis, and disease: supplementary issue: stem cell biology CE Rupert, KLK Coulombe Biomarker insights 10, BMI. S20061, 2015 | 99 | 2015 |
IGF1 and NRG1 enhance proliferation, metabolic maturity, and the force-frequency response in hESC-derived engineered cardiac tissues CE Rupert, KLK Coulombe Stem cells international 2017, 2017 | 75 | 2017 |
Engineered human myocardium with local release of angiogenic proteins improves vascularization and cardiac function in injured rat hearts F Munarin, RJ Kant, CE Rupert, A Khoo, KLK Coulombe Biomaterials 251, 120033, 2020 | 43 | 2020 |
Human cardiac fibroblast number and activation state modulate electromechanical function of hiPSC-cardiomyocytes in engineered myocardium CE Rupert, TY Kim, BR Choi, KLK Coulombe Stem cells international 2020, 2020 | 28 | 2020 |
Activation of the unfolded protein response downregulates cardiac ion channels in human induced pluripotent stem cell-derived cardiomyocytes M Liu, G Shi, A Zhou, CE Rupert, KLK Coulombe, SC Dudley Jr Journal of molecular and cellular cardiology 117, 62-71, 2018 | 26 | 2018 |
Hypertrophy changes 3D shape of hiPSC-cardiomyocytes: implications for cellular maturation in regenerative medicine CE Rupert, HH Chang, KLK Coulombe Cellular and molecular bioengineering 10, 54-62, 2017 | 22 | 2017 |
Practical adoption of state-of-the-art hiPSC-cardiomyocyte differentiation techniques CE Rupert, C Irofuala, KLK Coulombe PLoS One 15 (3), e0230001, 2020 | 19 | 2020 |
A human in vitro cardiotoxicity model KLK Coulombe, CE Rupert, CM Kofron, C Bum-Rak, T Kim, U Mende US Patent App. 17/611,064, 2022 | 1 | 2022 |
Acute Treatment With Aficamten Rescues Contractile Function in a MyoPod Engineered Heart Tissue Model of Hypertrophic Cardiomyopathy C Rupert, M Raval, JJ Hartman, AN Murphy, B Morgan, SG Campbell CIRCULATION RESEARCH 133 (12), E68-E68, 2023 | | 2023 |
Auxotonic MyoPod® Engineered Heart Tissues Enable Longitudinal Tracking of in vitro Development of Hypertrophic Cardiomyopathy C Rupert, B Archer, V Dau, S Cirilli, xia li, SG Campbell Circulation 148 (Suppl_1), A17931-A17931, 2023 | | 2023 |
EDG-7500, a Novel Cardiac Sarcomere Regulator That Preserves Intrinsic Myosin-Motor Function, Improves Cardiac Function and Reserve in a Minipig Model of Hypertrophic … CL Del Rio, C Rupert, J Tolley, M Duvall, C Emter, E DiNatale, ... Circulation 148 (Suppl_1), A15612-A15612, 2023 | | 2023 |
Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models: Increased length-dependent activation of human engineered heart … C Rupert, JE López, E Cortez-Toledo, O De la Cruz Cabrera, NC Chesler, ... American Journal of Physiology-Heart and Circulatory Physiology 324 (3), H293, 2023 | | 2023 |
Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy C Rupert, JE Lopez, E Cortez-Toledo, O De la Cruz Cabrera, NC Chesler, ... American Journal of Physiology-Heart and Circulatory Physiology 324 (3 …, 2023 | | 2023 |
Altered Contractile Phenotype and Sensitivity to Mavacamten in Engineered Heart Tissues With a Hypertrophic Cardiomyopathy Mutation C Rupert, B Archer, V Dau, S Cirilli, X Li, SG Campbell CIRCULATION RESEARCH 131 (12), E175-E175, 2022 | | 2022 |
Stretch Reduces Interfilament Spacing And Triggers Alterations In Thick-filament Structure In Healthy Left-atrial Fibers W Ma, M Papadaki, JA Kirk, C Rupert, CL del Rio, TC Irving CIRCULATION RESEARCH 131, 2022 | | 2022 |
Abstract P1056: Stretch Reduces Inter-filament Spacing And Triggers Alterations In Thick-filament Structure In Healthy Left-atrial Fibers W Ma, M Papadaki, JA Kirk, C Rupert, CL del Rio, TC Irving Circulation Research 131 (Suppl_1), AP1056-AP1056, 2022 | | 2022 |
Decellularized Lung Tissue Proteomics Showed Decreased Surfactant and Increased Inflammatory Proteins in the Aged Lung JE Mcdonough, C Cosme Jr, C Rupert, JC Schupp, F Ahangari, G DeIuliis, ... C29. SENESCENCE, SENOLYTICS, AND AGING IN LUNG BIOLOGY, A3903-A3903, 2022 | | 2022 |
Increased length-dependent activation of human engineered heart tissue after chronic treatment with alpha-1A-adrenergic agonist C Rupert, E Cortez-Toledo, JE Lopez, NC Chesler, PC Simpson, ... Biophysical Journal 121 (3), 397a-398a, 2022 | | 2022 |
Acute Pacing Regimen Strengthens Engineered Human Cardiac Tissue C Rupert, K Li, S Cirilli, X Li, S Campbell Circulation 144 (Suppl_1), A14185-A14185, 2021 | | 2021 |
2D and 3D Assessment of Angiogenesis in Cardiac Engineered Tissues Implanted on Infarcted Rat Hearts F Munarin, RJ Kant, CE Rupert, A Khoo, KL Coulombe Circulation Research 125 (Suppl_1), A716-A716, 2019 | | 2019 |