| Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease JS Butler, E Koutelou, AC Schibler, SYR Dent Epigenomics 4 (2), 163-177, 2012 | 146 | 2012 |
| Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein DL Carlone, JH Lee, SRL Young, E Dobrota, JS Butler, J Ruiz, DG Skalnik Molecular and cellular biology 25 (12), 4881-4891, 2005 | 119 | 2005 |
| Excision of expanded GAA repeats alleviates the molecular phenotype of Friedreich's ataxia Y Li, U Polak, AD Bhalla, N Rozwadowska, JS Butler, DR Lynch, ... Molecular Therapy 23 (6), 1055-1065, 2015 | 97 | 2015 |
| Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus Y Li, Y Lu, U Polak, K Lin, J Shen, J Farmer, L Seyer, AD Bhalla, ... Human molecular genetics 24 (24), 6932-6943, 2015 | 77 | 2015 |
| The role of chromatin modifiers in normal and malignant hematopoiesis JS Butler, SYR Dent Blood, The Journal of the American Society of Hematology 121 (16), 3076-3084, 2013 | 66 | 2013 |
| Somatic instability of the expanded GAA repeats in Friedreich's ataxia A Long, JS Napierala, U Polak, L Hauser, AH Koeppen, DR Lynch, ... PLoS One 12 (12), e189990, 2017 | 65 | 2017 |
| CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes JS Butler, JH Lee, DG Skalnik DNA and cell biology 27 (10), 533-543, 2008 | 60 | 2008 |
| Stalled DNA replication forks at the endogenous GAA repeats drive repeat expansion in Friedreich’s ataxia cells J Gerhardt, AD Bhalla, JS Butler, JW Puckett, PB Dervan, Z Rosenwaks, ... Cell reports 16 (5), 1218-1227, 2016 | 57 | 2016 |
| Therapeutic Prospects for Friedreich's Ataxia S Zhang, M Napierala, JS Napierala Trends in Pharmaceutical Sciences 40 (4), 229-233, 2019 | 44 | 2019 |
| Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers JS Napierala, Y Li, Y Lu, K Lin, LA Hauser, DR Lynch, M Napierala Disease models & mechanisms 10 (11), 1353-1369, 2017 | 44 | 2017 |
| Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis LA Bonsignore, JS Butler, CM Klinge, CES Tooley Oncotarget 6 (14), 12248, 2015 | 38 | 2015 |
| Protein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexes JS Butler, CI Zurita-Lopez, SG Clarke, MT Bedford, SYR Dent Journal of Biological Chemistry 286 (14), 12234-12244, 2011 | 38 | 2011 |
| Excision of the expanded GAA repeats corrects cardiomyopathy phenotypes of iPSC-derived Friedreich's ataxia cardiomyocytes J Li, N Rozwadowska, A Clark, D Fil, JS Napierala, M Napierala Stem cell research 40, 101529, 2019 | 33 | 2019 |
| Selected missense mutations impair frataxin processing in Friedreich ataxia E Clark, JS Butler, CJ Isaacs, M Napierala, DR Lynch Annals of clinical and translational neurology 4 (8), 575-584, 2017 | 30 | 2017 |
| Establishment and maintenance of primary fibroblast repositories for rare diseases—Friedreich's ataxia example Y Li, U Polak, AD Clark, AD Bhalla, YY Chen, J Li, J Farmer, L Seyer, ... Biopreservation and biobanking 14 (4), 324-329, 2016 | 28 | 2016 |
| Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming U Polak, Y Li, JS Butler, M Napierala Stem Cells and Development 25 (23), 1788-1800, 2016 | 27 | 2016 |
| Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia JS Butler, YH Qiu, N Zhang, SY Yoo, KR Coombes, SYR Dent, ... Leukemia & lymphoma 58 (5), 1207-1218, 2017 | 25 | 2017 |
| Friedreich's ataxia–a case of aberrant transcription termination? JS Butler, M Napierala Transcription 6 (2), 33-36, 2015 | 24 | 2015 |
| The current state of biomarker research for Friedreich’s ataxia: a report from the 2018 FARA biomarker meeting IA Blair, J Farmer, S Hersch, J Larkindale, DR Lynch, J Napierala, ... Future science OA 5 (6), FSO398, 2019 | 21 | 2019 |
| DNA Methyltransferase Protein Synthesis Is Reduced in CXXC Finger Protein 1–Deficient Embryonic Stem Cells JS Butler, LR Palam, CM Tate, JR Sanford, RC Wek, DG Skalnik DNA and cell biology 28 (5), 223-231, 2009 | 20 | 2009 |
