Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ... Science translational medicine 12 (545), eaay1359, 2020 | 219 | 2020 |
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice JC Ullman, A Arguello, JA Getz, A Bhalla, CS Mahon, J Wang, T Giese, ... Science Translational Medicine 12 (545), eaay1163, 2020 | 144 | 2020 |
Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation F Liao, A Li, M Xiong, N Bien-Ly, H Jiang, Y Zhang, MB Finn, R Hoyle, ... The Journal of clinical investigation 128 (5), 2144-2155, 2018 | 141 | 2018 |
Protease-resistant peptide ligands from a knottin scaffold library JA Getz, JJ Rice, PS Daugherty ACS chemical biology 6 (8), 837-844, 2011 | 120 | 2011 |
Site-specific targeting of antibody activity in vivo mediated by disease-associated proteases O Erster, JM Thomas, J Hamzah, AM Jabaiah, JA Getz, TD Schoep, ... Journal of controlled release 161 (3), 804-812, 2012 | 81 | 2012 |
Design of a cyclotide antagonist of neuropilin-1 and-2 that potently inhibits endothelial cell migration JA Getz, O Cheneval, DJ Craik, PS Daugherty ACS chemical biology 8 (6), 1147-1154, 2013 | 80 | 2013 |
Peptide discovery using bacterial display and flow cytometry JA Getz, TD Schoep, PS Daugherty Methods in enzymology 503, 75-97, 2012 | 52 | 2012 |
Identifi cation of protease exosite-interacting peptides that enhance substrate cleavage kinetics AM Jabaiah, JA Getz, WA Witkowski, JA Hardy, PS Daugherty Biological chemistry 393 (9), 933-941, 2012 | 30 | 2012 |
A novel quantitative kinase assay using bacterial surface display and flow cytometry ST Henriques, L Thorstholm, YH Huang, JA Getz, PS Daugherty, DJ Craik PloS one 8 (11), e80474, 2013 | 23 | 2013 |
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice. Sci Transl Med 12: eaay1163 JC Ullman, A Arguello, JA Getz, A Bhalla, CS Mahon, J Wang, T Giese, ... | 9 | 2020 |
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys. Sci Transl Med 12: eaay1359 MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ... | 9 | 2020 |
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys. Sci Transl Med. 2020 MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ... | 7 | |
Affinity-based methods for using transferrin receptor-binding proteins MS Dennis, J Getz, M Kariolis, AP Silverman, RC Wells, JY Zuchero US Patent App. 16/782,984, 2020 | 6 | 2020 |
Fusion proteins comprising enzyme replacement therapy enzymes A Henry, MS Kariolis, CS Mahon, AP Silverman, A Srivastava, J Ullman US Patent 11,866,742, 2024 | 5* | 2024 |
Biomarkers for h-nox delivery of oxygen SPL Cary, A Krtolica, N Le Moan, L Serwer, JA Getz US Patent App. 14/530,569, 2015 | 5 | 2015 |
Rice JJ Daugherty PS ACS Chem JA Getz Biol 6, 837-844, 2011 | 3 | 2011 |
Biol. 2011, 6, 837–844; b) JA Getz, O JA Getz, JJ Rice, PS Daugherty Cheneval, DJ Craik, PS Daugherty, ACS Chem. Biol 8, 1147-1154, 2013 | 2 | 2013 |
Nonclinical pharmacokinetics, pharmacodynamics and safety assessment of a FLT3L-Fc molecule for cancer immunotherapy KC Wu, AO Adedeji, TS Zabka, I Hosseini, R Kenkre, JA Getz, T Nguyen, ... Toxicology and Applied Pharmacology 483, 116837, 2024 | 1 | 2024 |
Neutropenia in Cynomolgus Monkeys With Anti-Drug Antibodies Associated With Administration of Afucosylated Humanized Monoclonal Antibodies AO Adedeji, F Zhong, JA Getz, Z Zhong, W Halpern Toxicologic Pathology 50 (8), 910-919, 2022 | 1 | 2022 |
Brain delivery and efficacy of an intravenously-administered lysosomal enzyme using a blood-brain barrier transport vehicle AG Henry, J Ullman, A Arguello, J Getz, A Bhalla, C Mahon, J Wang, ... Molecular Genetics and Metabolism 129 (2), S72, 2020 | 1 | 2020 |