Antibody–PROTAC conjugates enable HER2-dependent targeted protein degradation of BRD4 M Maneiro, N Forte, MM Shchepinova, CS Kounde, V Chudasama, ... ACS chemical biology 15 (6), 1306-1312, 2020 | 189 | 2020 |
A caged E3 ligase ligand for PROTAC-mediated protein degradation with light CS Kounde, MM Shchepinova, CN Saunders, M Muelbaier, MD Rackham, ... Chemical communications 56 (41), 5532-5535, 2020 | 87 | 2020 |
Discovery of tetrahydropyrazolopyrimidine carboxamide derivatives as potent and orally active antitubercular agents F Yokokawa, G Wang, WL Chan, SH Ang, J Wong, I Ma, SPS Rao, ... ACS Medicinal Chemistry Letters 4 (5), 451-455, 2013 | 54 | 2013 |
NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models SA Moquin, O Simon, R Karuna, SB Lakshminarayana, F Yokokawa, ... Science translational medicine 13 (579), eabb2181, 2021 | 48 | 2021 |
PROTACs, molecular glues and bifunctionals from bench to bedside: Unlocking the clinical potential of catalytic drugs M Maneiro, E De Vita, D Conole, CS Kounde, Q Zhang, EW Tate Progress in medicinal chemistry 60, 67-190, 2021 | 23 | 2021 |
Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit CS Kounde, HQ Yeo, QY Wang, KF Wan, H Dong, R Karuna, I Dix, ... Bioorganic & medicinal chemistry letters 27 (6), 1385-1389, 2017 | 20 | 2017 |
Desymmetrization of hydrazinocyclohexadienes: A new approach for the synthesis of polyhydroxylated aminocyclohexanes G Errasti, C Koundé, O Mirguet, T Lecourt, L Micouin Organic Letters 11 (13), 2912-2915, 2009 | 19 | 2009 |
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs) ED Vita Chemical Communications 58 (78), 10933-10936, 2022 | 15 | 2022 |
Photoactive Bifunctional Degraders: Precision Tools To Regulate Protein Stability: Miniperspective CS Kounde, EW Tate Journal of Medicinal Chemistry 63 (24), 15483-15493, 2020 | 11 | 2020 |
Bifunctional chemical tools for the conditional control of targeted protein degradation CS Kounde Imperial College London, 2023 | | 2023 |