| Comparative metabolic capabilities and inhibitory profiles of CYP2D6. 1, CYP2D6. 10, and CYP2D6. 17 H Shen, MM He, H Liu, SA Wrighton, L Wang, B Guo, C Li Drug Metabolism and Disposition, 2007 | 209 | 2007 |
| Psychedelic 5-methoxy-N, N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions HW Shen, XL Jiang, J C Winter, AM Yu Current drug metabolism 11 (8), 659-666, 2010 | 189 | 2010 |
| Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo M Huang, H Gao, Y Chen, H Zhu, Y Cai, X Zhang, Z Miao, H Jiang, ... Clinical cancer research 13 (4), 1298-1307, 2007 | 125 | 2007 |
| Determination of saikosaponin derivatives in Radix bupleuri and in pharmaceuticals of the chinese multiherb remedy xiaochaihu-tang using liquid chromatographic tandem mass … Y Bao, C Li, H Shen, F Nan Analytical chemistry 76 (14), 4208-4216, 2004 | 95 | 2004 |
| Fully Validated LC-MS/MS Assay for the Simultaneous Quantitation of Coadministered Therapeutic Antibodies in Cynomolgus Monkey Serum H Jiang, J Zeng, C Titsch, K Voronin, B Akinsanya, L Luo, H Shen, ... Analytical chemistry 85 (20), 9859-9867, 2013 | 88 | 2013 |
| Pinoline may be used as a probe for CYP2D6 activity XL Jiang, HW Shen, AM Yu Drug Metabolism and Disposition 37 (3), 443-446, 2009 | 71 | 2009 |
| Altered expression of small heterodimer partner governs cytochrome P450 (CYP) 2D6 induction during pregnancy in CYP2D6-humanized mice KH Koh, X Pan, HW Shen, SLM Arnold, AM Yu, FJ Gonzalez, ... Journal of Biological Chemistry 289 (6), 3105-3113, 2014 | 53 | 2014 |
| Altered expression of small heterodimer partner governs cytochrome P450 (CYP) 2D6 induction during pregnancy in CYP2D6-humanized mice KH Koh, X Pan, HW Shen, SLM Arnold, AM Yu, FJ Gonzalez, ... Journal of Biological Chemistry 289 (6), 3105-3113, 2014 | 53 | 2014 |
| Effects of CYP2D6 status on harmaline metabolism, pharmacokinetics and pharmacodynamics, and a pharmacogenetics-based pharmacokinetic model C Wu, XL Jiang, HW Shen, AM Yu Biochemical pharmacology 78 (6), 617-624, 2009 | 51 | 2009 |
| Effects of monoamine oxidase inhibitor and cytochrome P450 2D6 status on 5-methoxy-N,N-dimethyltryptamine metabolism and pharmacokinetics HW Shen, C Wu, XL Jiang, AM Yu Biochemical pharmacology 80 (1), 122-128, 2010 | 42 | 2010 |
| The riboswitch regulates a thiamine pyrophosphate ABC transporter of the oral spirochete Treponema denticola J Bian, H Shen, Y Tu, A Yu, C Li Journal of bacteriology 193 (15), 3912-3922, 2011 | 37 | 2011 |
| Humanized transgenic mouse models for drug metabolism and pharmacokinetic research HW Shen, XL Jiang, F J Gonzalez, AM Yu Current drug metabolism 12 (10), 997-1006, 2011 | 31 | 2011 |
| Nonlinear pharmacokinetics of 5-methoxy-N, N-dimethyltryptamine in mice HW Shen, XL Jiang, AM Yu Drug Metabolism and Disposition 39 (7), 1227-1234, 2011 | 29 | 2011 |
| Nonlinear pharmacokinetics of 5-methoxy-N, N-dimethyltryptamine in mice HW Shen, XL Jiang, AM Yu Drug Metabolism and Disposition 39 (7), 1227-1234, 2011 | 29 | 2011 |
| Pharmacokinetic interactions between monoamine oxidase A inhibitor harmaline and 5-methoxy-N, N-dimethyltryptamine, and the impact of CYP2D6 status XL Jiang, HW Shen, DE Mager, AM Yu Drug Metabolism and Disposition 41 (5), 975-986, 2013 | 26 | 2013 |
| Potentiation of 5-methoxy-N,N-dimethyltryptamine-induced hyperthermia by harmaline and the involvement of activation of 5-HT1A and 5-HT2A receptors XL Jiang, HW Shen, AM Yu Neuropharmacology 89, 342-351, 2015 | 25 | 2015 |
| Development of a LC-MS/MS method to analyze 5-methoxy-N, N-dimethyltryptamine and bufotenine: application to pharmacokinetic study HW Shen, XL Jiang, AM Yu Future Science Ltd 1 (1), 87-95, 2009 | 21 | 2009 |
| Synthesis and antitumor activity of the hexacyclic camptothecin derivatives H Gao, X Zhang, Y Chen, H Shen, T Pang, J Sun, C Xu, J Ding, C Li, W Lu Bioorganic & medicinal chemistry letters 15 (13), 3233-3236, 2005 | 21 | 2005 |
| Synthesis and antitumor activity of 7-ethyl-9-alkyl derivatives of camptothecin H Gao, X Zhang, Y Chen, H Shen, J Sun, M Huang, J Ding, C Li, W Lu Bioorganic & medicinal chemistry letters 15 (8), 2003-2006, 2005 | 16 | 2005 |
| Modification of 5-methoxy-N, N-dimethyltryptamine-induced hyperactivity by monoamine oxidase A inhibitor harmaline in mice and the underlying serotonergic mechanisms XL Jiang, HW Shen, AM Yu Pharmacological Reports 68 (3), 608-615, 2016 | 12 | 2016 |
