| Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis JT Marinko, H Huang, WD Penn, JA Capra, JP Schlebach, CR Sanders Chemical reviews 119 (9), 5537-5606, 2019 | 200 | 2019 |
| Simplified proteomics approach to discover protein–ligand interactions Y Chang, JP Schlebach, RA VerHeul, C Park Protein Science 21 (9), 1280-1287, 2012 | 73 | 2012 |
| Peripheral myelin protein 22 alters membrane architecture KF Mittendorf, JT Marinko, CM Hampton, Z Ke, A Hadziselimovic, ... Science advances 3 (7), e1700220, 2017 | 61 | 2017 |
| Conformational stability and pathogenic misfolding of the integral membrane protein PMP22 JP Schlebach, M Narayan, C Alford, KF Mittendorf, BD Carter, J Li, ... Journal of the American Chemical Society 137 (27), 8758-8768, 2015 | 57 | 2015 |
| Probing membrane protein unfolding with pulse proteolysis JP Schlebach, MS Kim, NH Joh, JU Bowie, C Park Journal of molecular biology 406 (4), 545-551, 2011 | 46 | 2011 |
| The safety dance: biophysics of membrane protein folding and misfolding in a cellular context JP Schlebach, CR Sanders Quarterly reviews of biophysics 48 (1), 1-34, 2015 | 44 | 2015 |
| Revisiting the folding kinetics of bacteriorhodopsin JP Schlebach, Z Cao, JU Bowie, C Park Protein Science 21 (1), 97-106, 2012 | 41 | 2012 |
| Cotranslational folding stimulates programmed ribosomal frameshifting in the alphavirus structural polyprotein HR Harrington, MH Zimmer, LM Chamness, V Nash, WD Penn, TF Miller, ... Journal of Biological Chemistry 295 (20), 6798-6808, 2020 | 40 | 2020 |
| Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein JP Schlebach, D Peng, BM Kroncke, KF Mittendorf, M Narayan, BD Carter, ... Biochemistry 52 (19), 3229-3241, 2013 | 40 | 2013 |
| Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning WD Penn, AG McKee, CP Kuntz, H Woods, V Nash, TC Gruenhagen, ... Science advances 6 (10), eaay7505, 2020 | 35 | 2020 |
| Bacteriorhodopsin folds through a poorly organized transition state JP Schlebach, NB Woodall, JU Bowie, C Park Journal of the American Chemical Society 136 (47), 16574-16581, 2014 | 29 | 2014 |
| Modest effects of lipid modifications on the structure of caveolin-3 JH Kim, D Peng, JP Schlebach, A Hadziselimovic, CR Sanders Biochemistry 53 (27), 4320-4322, 2014 | 29 | 2014 |
| Regulators of viral frameshifting: more than RNA influences translation events WD Penn, HR Harrington, JP Schlebach, S Mukhopadhyay Annual review of virology 7, 219-238, 2020 | 24 | 2020 |
| Influence of pathogenic mutations on the energetics of translocon-mediated bilayer integration of transmembrane helices JP Schlebach, CR Sanders The Journal of membrane biology 248, 371-381, 2015 | 24 | 2015 |
| Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state Z Cao, JP Schlebach, C Park, JU Bowie Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (4), 1049-1054, 2012 | 24 | 2012 |
| Topologically diverse human membrane proteins partition to liquid-disordered domains in phase-separated lipid vesicles JP Schlebach, PJ Barrett, CA Day, JH Kim, AK Kenworthy, CR Sanders Biochemistry 55 (7), 985-988, 2016 | 23 | 2016 |
| Contribution of cotranslational folding defects to membrane protein homeostasis FJ Roushar, TC Gruenhagen, WD Penn, B Li, J Meiler, B Jastrzebska, ... Journal of the American Chemical Society 141 (1), 204-215, 2018 | 22 | 2018 |
| The retinitis pigmentosa-linked mutations in transmembrane helix 5 of rhodopsin disrupt cellular trafficking regardless of oligomerization state DP Mallory, E Gutierrez, M Pinkevitch, C Klinginsmith, WD Comar, ... Biochemistry 57 (35), 5188-5201, 2018 | 20 | 2018 |
| Classification of the Molecular Defects Associated with Pathogenic Variants of the SLC6A8 Creatine Transporter MD Salazar, NB Zelt, R Saldivar, CP Kuntz, S Chen, WD Penn, ... Biochemistry 59 (13), 1367-1377, 2020 | 17 | 2020 |
| Glycosylation limits forward trafficking of the tetraspan membrane protein PMP22 JT Marinko, MT Wright, JP Schlebach, KR Clowes, DR Heintzman, L Plate, ... Journal of Biological Chemistry 296, 2021 | 15 | 2021 |
Charles R. SandersProfessor of Biochemistry, Vanderbilt UniversityVerified email at vanderbilt.edu
