| Temozolomide resistance in glioblastoma cell lines: implication of MGMT, MMR, P-glycoprotein and CD133 expression G Perazzoli, J Prados, R Ortiz, O Caba, L Cabeza, M Berdasco, ... PloS one 10 (10), e0140131, 2015 | 198 | 2015 |
| Electrospun nanofibers: Recent applications in drug delivery and cancer therapy R Contreras-Cáceres, L Cabeza, G Perazzoli, A Díaz, JM López-Romero, ... Nanomaterials 9 (4), 656, 2019 | 141 | 2019 |
| Mechanistic differences in neuropathic pain modalities revealed by correlating behavior with global expression profiling EJ Cobos, CA Nickerson, F Gao, V Chandran, I Bravo-Caparrós, ... Cell reports 22 (5), 1301-1312, 2018 | 130 | 2018 |
| MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy C Melguizo, J Prados, B González, R Ortiz, A Concha, PJ Alvarez, ... Journal of translational medicine 10, 1-11, 2012 | 96 | 2012 |
| Differentiation of human mesenchymal stem cells towards neuronal lineage: clinical trials in nervous system disorders R Hernández, C Jiménez-Luna, J Perales-Adán, G Perazzoli, C Melguizo, ... Biomolecules & therapeutics 28 (1), 34, 2020 | 95 | 2020 |
| The challenge of drug resistance in pancreatic ductal adenocarcinoma: a current overview F Quiñonero, C Mesas, K Doello, L Cabeza, G Perazzoli, C Jimenez-Luna, ... Cancer biology & medicine 16 (4), 688, 2019 | 87 | 2019 |
| Sigma-1 receptor inhibition reverses acute inflammatory hyperalgesia in mice: role of peripheral sigma-1 receptors MÁ Tejada, Á Montilla-García, C Sánchez-Fernández, JM Entrena, ... Psychopharmacology (Berl) 231 (19), 3855-3869, 2014 | 70 | 2014 |
| Temozolomide: an updated overview of resistance mechanisms, nanotechnology advances and clinical applications R Ortiz, G Perazzoli, L Cabeza, C Jiménez-Luna, R Luque, J Prados, ... Current neuropharmacology 19 (4), 513-537, 2021 | 66 | 2021 |
| Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia Á Montilla-García, MÁ Tejada, G Perazzoli, JM Entrena, E Portillo-Salido, ... Neuropharmacology 125, 231-242, 2017 | 64 | 2017 |
| Improved antitumor activity and reduced toxicity of doxorubicin encapsulated in poly (ε-caprolactone) nanoparticles in lung and breast cancer treatment: An in vitro and in vivo … L Cabeza, R Ortiz, J Prados, ÁV Delgado, MJ Martín-Villena, B Clares, ... European Journal of Pharmaceutical Sciences 102, 24-34, 2017 | 62 | 2017 |
| Cancer therapy based on extracellular vesicles as drug delivery vehicles L Cabeza, G Perazzoli, M Peña, A Cepero, C Luque, C Melguizo, ... Journal of controlled release 327, 296-315, 2020 | 54 | 2020 |
| Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury I Bravo Caparrós, MC Ruiz Cantero, G Perazzoli, SFJ Cronin, JM Vela, ... | 49 | 2020 |
| A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer J Jiménez-López, MM El-Hammadi, R Ortiz, MD Cayero-Otero, L Cabeza, ... Pharmacological Research 141, 451-465, 2019 | 47 | 2019 |
| Sigma-1 receptor inhibition reduces neuropathic pain induced by partial sciatic nerve transection in mice by opioid-dependent and-independent mechanisms I Bravo-Caparrós, G Perazzoli, S Yeste, D Cikes, JM Baeyens, EJ Cobos, ... Frontiers in pharmacology 10, 613, 2019 | 44 | 2019 |
| Colon cancer therapy: recent developments in nanomedicine to improve the efficacy of conventional chemotherapeutic drugs J Prados, C Melguizo, R Ortiz, G Perazzoli, L Cabeza, P J Alvarez, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2013 | 41 | 2013 |
| Nanoparticles in Colorectal Cancer Therapy: Latest In Vivo Assays, Clinical Trials, and Patents L Cabeza, G Perazzoli, C Mesas, C Jiménez-Luna, J Prados, AR Rama, ... AAPS PharmSciTech 21, 1-15, 2020 | 40 | 2020 |
| Formulation and in vitro evaluation of magnetoliposomes as a potential nanotool in colorectal cancer therapy C Lorente, L Cabeza, B Clares, R Ortiz, L Halbaut, ÁV Delgado, ... Colloids and Surfaces B: Biointerfaces 171, 553-565, 2018 | 39 | 2018 |
| Tripalmitin nanoparticle formulations significantly enhance paclitaxel antitumor activity against breast and lung cancer cells in vitro MC Leiva, R Ortiz, R Contreras-Cáceres, G Perazzoli, I Mayevych, ... Scientific Reports 7 (1), 13506, 2017 | 39 | 2017 |
| Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes J Jiménez-López, I Bravo-Caparrós, L Cabeza, FR Nieto, R Ortiz, ... Biomedicine & Pharmacotherapy 133, 111059, 2021 | 37 | 2021 |
| Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain MC Ruiz-Cantero, R González-Cano, MÁ Tejada, M Santos-Caballero, ... Pharmacological research 163, 105339, 2021 | 36 | 2021 |
